Dilated cardiomyopathy trials in United States

In United States 16 Also abroad 66

16 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.

Phase 2/3Taking people
A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy
Where
Baltimore, Birmingham, Boston, Chicago, Cincinnati, Columbus, Detroit, Durham, Houston, Jacksonville, Kansas City, Los Angeles, Minneapolis, Nashville, New Orleans, New York, Omaha, Philadelphia, Portland, Rochester, San Diego, San Francisco, Stanford, St Louis, Washington D.C.
Age
18 years and over
People
332 worldwide
Run by
Kardigan, Inc.
See details and how to joinNCT07210723
Phase 3Taking people
A Study of the Long-term Safety and Efficacy of Danicamtiv in Adults With Symptomatic Genetic and Familial Dilated Cardiomyopathy
Where
Baltimore, Birmingham, Boston, Chicago, Cincinnati, Columbus, Detroit, Durham, Houston, Jacksonville, Kansas City, Los Angeles, Minneapolis, Nashville, New Orleans, New York, Omaha, Philadelphia, Portland, Rochester, San Diego, San Francisco, Stanford, St Louis, Washington D.C.
Age
18 years and over
People
332 worldwide
Run by
Kardigan, Inc.
See details and how to joinNCT07771465
Phase 1/2Taking people
An AAV Gene Therapy Trial of AFTX-201 in Adults With BAG3-Associated Dilated Cardiomyopathy (DCM)
Where
Houston, Kansas City, Miami, New York
Age
18 years to 70 years
People
22 worldwide
Run by
Affinia Therapeutics
See details and how to joinNCT07426419
No phaseTaking people
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
Where
Sioux Falls
People
20,000
Run by
Sanford Health
See details and how to joinNCT01793168
Phase 1Taking people
A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy
Where
Charleston, Rochester, San Diego
Age
18 years to 65 years
People
8
Run by
Rocket Pharmaceuticals Inc.
See details and how to joinNCT07137338
Phase 1/2Taking people
ALXN2350 in Adult Participants With BAG3-Associated Dilated Cardiomyopathy
Where
Birmingham, Boston, Cincinnati, Houston, Palo Alto, Philadelphia, Portland
Age
18 years to 70 years
People
6 worldwide
Run by
Alexion Pharmaceuticals, Inc.
See details and how to joinNCT07218887 · EU 2024-519674-40-00
No phaseTaking people
Study of the Progression of Chronic Cardiovascular Conditions
Where
Chicago
Age
18 years and over
People
5,000
Run by
Prolaio
See details and how to joinNCT07420907
Phase 1/2Taking people
A Study With NVC-001 in Patients With LMNA-related Dilated Cardiomyopathy (SUNBEAM-LMNA)
Where
Ann Arbor, Birmingham, Boston, Cincinnati, Columbus, Houston, Los Angeles, Rochester
Age
18 years and over
People
21
Run by
Nuevocor Pte. Ltd.
See details and how to joinNCT07606274 · EU 2025-524828-21-00
Phase 1Taking people
A Phase 1 Open-Label Study of the Safety of Intravenous Allogeneic Neonatal Mesenchymal Cells (nMSCs) in Young Adult (1A) and Pediatric (1B) Patients With Dilated Cardiomyopathy (DCM)
Where
Atlanta
Age
4 years to 40 years
People
36
Run by
Emory University
See details and how to joinNCT06464588
No phaseTaking people
Pediatric Cardiomyopathy Mutation Analysis
Where
Indianapolis
People
300
Run by
Indiana University
See details and how to joinNCT02432092
No phaseTaking people
AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor
Where
Austin, Detroit, Greensboro, Hackensack, New York, Orange, Pasadena, Weslaco
Age
18 years and over
People
2,000
Run by
Peerbridge Health, Inc
See details and how to joinNCT06699056
No phaseTaking people
Mayo AVC Registry and Biobank
Where
Rochester
People
1,000 worldwide
Run by
Mayo Clinic
See details and how to joinNCT03049254
No phaseEnrolling by invitation
Derivation of Human Induced Pluripotent Stem (iPS) Cells to Heritable Cardiac Arrhythmias
Where
Baltimore
Age
18 years to 85 years
People
100
Run by
Johns Hopkins University
See details and how to joinNCT02413450
No phaseTaking people
UIC Multi-Ethnic DCM Registry
Where
Chicago
Age
18 years and over
People
1,500
Run by
University of Illinois Chicago
See details and how to joinNCT07145138
Phase 1Taking people
Modulation of SERCA2a of Intra-Myocytic Calcium Trafficking in Cardiomyopathy Secondary to Duchenne Muscular Dystrophy
Where
Cincinnati, Columbus, Kansas City
Age
18 years and over
People
12
Run by
Sardocor Corp.
See details and how to joinNCT06224660
No phaseTaking people
Dilated Cardiomyopathy Detection Using AI and Screening With Mobile Technology (DCM-DETECT)
Where
Lancaster
Age
18 years and over
People
150
Run by
Lancaster General Hospital
See details and how to joinNCT06688396