Endometrial cancer trials in Germany

In Germany 32 Also abroad 395

32 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer
Where
Berlin, Bonn, Dresden, Essen, Kassel, Leipzig, Munich, Tuebingen
Age
18 years and over
People
480 worldwide
Run by
BioNTech SE
See details and how to joinNCT06340568 · EU 2023-507525-42-00
Phase 3Taking people
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
Where
Aachen, Berlin, Bonn, Dessau-Rosslau, Detmold, Dresden, Hamburg, Jena, Kassel, Kiel, Leipzig, Muenster, Munich, Saarbruecken, Trier
Age
18 years and over
People
1,123 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06952504 · EU 2024-519331-42-00
Phase 3Taking people
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
Where
Berlin, Bonn, Hamburg, Lemgo, Wiesbaden
Age
18 years and over
People
660 worldwide
Run by
Genmab
See details and how to joinNCT07166094
Phase 1/2Taking people
EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors
Where
Berlin, Deggendorf, Hamburg
Age
18 years and over
People
160 worldwide
Run by
Eikon Therapeutics
See details and how to joinNCT07262619 · EU 2026-525248-13-00
Phase 3Taking people
A Study of Trastuzumab Deruxtecan Versus Standard of Care Chemotherapy for HER2-Expressing (IHC 3+/2+) Endometrial Cancer in Adjuvant Setting
Where
Detmold, Dresden, Duesseldorf, Essen, Frankfurt Am Main, Freiburg, Hamburg, Ulm
Age
18 years and over
People
710 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT07022483 · EU 2024-519444-33-00
Phase 2Taking people
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Where
Frankfurt
Age
18 years and over
People
740 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06172478 · EU 2023-507641-29-00
Phase 1/2Taking people
A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)
Where
Berlin, Dresden, Heidelberg, Heilbronn, Leipzig, Mainz, Muenster
Age
18 years and over
People
680 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06330064 · EU 2023-509632-26-00
Phase 1/2Taking people
A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9
Where
Bochum, München, Ulm
Age
18 years and over
People
245 worldwide
Run by
BioNTech SE
See details and how to joinNCT07186842 · EU 2025-522613-26-00
Phase 2Taking people
Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER
Where
Schwäbisch Hall
Age
18 years and over
People
393 worldwide
Run by
Canadian Cancer Trials Group
See details and how to joinNCT05640999
Phase 3Taking people
DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer
Where
Berlin, Chemnitz, Dessau-Rosslau, Dresden, Essen, Hamburg, Kassel, Leipzig, Mannheim, Muenster, Saarbruecken
Age
18 years and over
People
600 worldwide
Run by
AstraZeneca
See details and how to joinNCT06989112 · EU 2023-508056-19-00
Phase 3Taking people
Refining Adjuvant Treatment IN Endometrial Cancer Based On Molecular Features
Where
Berlin, Detmold, Dresden, Essen, Hamburg, Heidelberg, Kempten (Allgau), Leipzig, Ludwigsburg, Muenster, Munich, Schwaebisch Hall, Tuebingen, Ulm, Winnenden, Worms
Age
18 years and over
People
316 worldwide
Run by
Leiden University Medical Center
See details and how to joinNCT05255653 · EU 2023-503267-42-00
Phase 1/2Taking people
Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
Where
Bayern, Berlin, Heidelberg, Mainz
Age
18 years to 130 years
People
695 worldwide
Run by
AstraZeneca
See details and how to joinNCT05417594 · EU 2023-504984-17-00
Phase 1/2Taking people
Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors
Where
Berlin, Essen, Freiburg im Breisgau, Hanover, Leipzig, Mannheim, Regensburg
Age
18 years to 130 years
People
622 worldwide
Run by
AstraZeneca
See details and how to joinNCT05797168 · EU 2022-502576-23-00
Phase 1/2Taking people
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
Where
Augsburg, Essen, Frankfurt am Main, Hamburg, Heidelberg
Age
12 years and over
People
300 worldwide
Run by
PMV Pharmaceuticals, Inc
See details and how to joinNCT04585750
Phase 3Taking people
A clinical trial of belzutifan and other treatments in people with solid tumors or von Hippel-Lindau (VHL)-related tumors (MK-6482-043)
Where
Magdeburg
Age
18 years and over
People
134 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to join2025-524160-38-00 · EU 2025-524160-38-00
No phaseTaking people
NIS to Examine the Effectiveness and Safety of Durvalumab and Olaparib in Patients With Endometrial Cancer (DUOLife)
Where
Amberg, Bad Nauheim, Bautzen, Berlin, Bielefeld, Bonn, Borna, Bottrop, Brandenburg an der Havel, Braunschweig, Cologne, Dessau, Dresden, Ebersberg, Eggenfelden, Essen, Goslar, Greifswald, Gütersloh, Hamburg, Heilbronn, Homburg, Hösbach, Kiel, Krefeld, Kulmbach, Landshut, Leipzig, Limburg, Lüneburg, Magdeburg, Mainz, München, Neuruppin, Neuss, Nuremberg, Plauen, Rotenburg (Wümme), Siegen, Solingen, Stendal, Torgau, Traunstein, Unna, Wernigerode, Winnenden, Witten, Worms, Zittau
Age
18 years to 130 years
People
150
Run by
AstraZeneca
See details and how to joinNCT06890273
Phase 2Taking people
Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
Where
Berlin, Essen, Hanover, München, Regensburg
Age
18 years to 130 years
People
454 worldwide
Run by
AstraZeneca
See details and how to joinNCT05489211 · EU 2023-509436-26-00
Phase 1/2Taking people
Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
Where
Cologne, Esslingen am Neckar, Moers, Nuremberg
Age
18 years and over
People
534 worldwide
Run by
Revolution Medicines, Inc.
See details and how to joinNCT06128551
No phaseTaking people
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Where
Hamburg, Heilbronn, Munich
Age
18 years and over
People
2,285 worldwide
Run by
Guardant Health, Inc.
See details and how to joinNCT05059444
Phase 2Taking people
A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma
Where
Essen, Muenster, Ulm
Age
18 years and over
People
350 worldwide
Run by
Acrivon Therapeutics
See details and how to joinNCT05548296 · EU 2025-524542-10-00
Phase 1Taking people
A Study to Test How Well Different Doses of BI 3820768 Are Tolerated by People With Advanced Cancer (Solid Tumours)
Where
Munich, Wuerzburg
Age
18 years and over
People
187 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT07306559 · EU 2025-522913-45-00
Phase 3Taking people
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator’s Choice in Participants With Endometrial Cancer ( RAINFOL-03 )
Where
Berlin, Bonn, Chemnitz, Cologne, Detmold, Dresden, Duesseldorf, Hamburg, Leipzig, Munich, Schwaebisch Hall, Wiesbaden
Age
18 years and over
People
290 worldwide
Run by
Genmab A/S
See details and how to join2024-519818-31-01 · EU 2024-519818-31-01
Phase 3Taking people
Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)
Where
Amberg, Detmold, Dresden, Essen, Freiburg im Breisgau, Hamburg, Heidelberg, Heilbronn, Kassel, Mainz, Muenster, Paderborn, Regensburg, Ulm, Witten
Age
18 years and over
People
800 worldwide
Run by
AstraZeneca
See details and how to joinNCT07044336 · EU 2024-518777-34-00
Phase 1Taking people
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
Where
Berlin
Age
18 years and over
People
714 worldwide
Run by
Seagen, a wholly owned subsidiary of Pfizer
See details and how to joinNCT05208762 · EU 2023-506604-18-00
Phase 2Taking people
Relacorilant in Combination With Different Treatment Regimens in Patients With Gynecological Cancers
Where
Aachen, Berlin, Kempten
Age
18 years and over
People
270 worldwide
Run by
Corcept Therapeutics
See details and how to joinNCT06906341