Epilepsy: open trials in United States

208 open trials have a site in United States. Registry data; only the trial team decides who can take part.

NCT00305305
Brain Development Research Program
Research · University of California, San Francisco
University of California San Francisco, San Francisco
Registry updated 2026-08-17
NCT07768618
Electrophysiologic Mechanisms of Ketamine Antidepressant Response
Trial Treatment · Phase 2 · Emory University
Emory University, Atlanta
Registry updated 2026-08-17
NCT06898138
Acute Stimulation and Modulation of Stereotyped High-Frequency Oscillations
Trial Treatment · Mayo Clinic
Baylor College of Medicine, Houston · Mayo Clinic, Rochester
Registry updated 2026-08-11
NCT06934356
Subcortical Arousal in Perceptual Awareness
Trial Treatment · Yale University
Massachusetts General Hospital, Boston · Baylor College of Medicine, Houston · University of Kansas Medical Center, Kansas City · Dartmouth Hitchcock Medical Center, Lebanon · Vanderbilt University Medical Center, Nashville · Yale School of Medicine, New Haven · University of Pittsburgh Medical Center, Pittsburgh · Mayo Clinic, Rochester
Registry updated 2026-08-10
NCT05794295
Sleep Architecture & Cognition in Focal Epilepsy
Trial Treatment · University of California, Davis
UC Davis, Sacramento
Registry updated 2026-08-07
NCT06391294
Neuronal and Network Mechanisms of Electrocortical Stimulation
Trial Treatment · Northwestern University
Johns Hopkins University, Baltimore · Northwestern University, Chicago · University of Iowa, Iowa City
Registry updated 2026-08-07
NCT06865820
Implementation and Cost Evaluation of Project UPLIFT
Trial Treatment · Emory University
Rollins School of Public Health, Atlanta
Registry updated 2026-08-07
NCT05374824
Comparative Effectiveness of Palliative Surgery Versus Additional Anti-Seizure Medications for Lennox-Gastaut Syndrome
Research · Ann & Robert H Lurie Children's Hospital of Chicago
C S Mott Children's Hospital, Ann Arbor · Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago · Nationwide Children's, Columbus · St. Louis Children's Hospital, St Louis
Registry updated 2026-08-06
NCT06716866
Temporally Interfering Electric Field Stimulation in the Treatment of Epilepsy
Trial Treatment · University of California, Davis
Emory University Hospital, Atlanta · UC Davis Medical Center, Sacramento
Registry updated 2026-08-06
NCT07555171
EEG Dynamics in Lennox-Gastaut Syndrome Patients Undergoing Fenfluramine Treatment
Research · University of Chicago
University of Chicago, Chicago
Registry updated 2026-08-06
NCT07750496
Outcomes After Planned Discontinuation of AntiSeizure Medication
Trial Treatment · Phase 4 · University of Michigan
University of Michigan, Ann Arbor
Registry updated 2026-08-06
NCT07019922
A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety
Trial Treatment · Phase 3 · Praxis Precision Medicines
Aurora · Chicago · Cincinnati · Memphis · Philadelphia · San Diego
Registry updated 2026-08-03
NCT07287163
Clinical Trial of Vormatrigine in Adult Patients With Epilepsy
Trial Treatment · Phase 3 · Praxis Precision Medicines
Amherst · Bethesda · Chesterfield · El Paso · Hackensack · Houston · Lafayette · Miami · Miami Lakes · Middletown · Naples · New York · Niagara Falls · Philadelphia · Plymouth
Registry updated 2026-08-03
NCT07531511
SLC6A1-NDD Prospective Longitudinal Natural History Study
Research · UCB Biopharma SRL
Gtep01 50614, New York
Registry updated 2026-07-31
NCT07271966
B6 Administration for Levetiracetam-Associated Neurobehavioral Changes and Epilepsy
Trial Treatment · Duke University
Duke University Medical Center, Durham
Registry updated 2026-07-29
NCT07594652
Medication Treatment of ADHD in Pediatric Epilepsy
Trial Treatment · Phase 4 · Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Kennedy Krieger Institute, Baltimore
Registry updated 2026-07-29
NCT04715646
A Study to Test the Safety and Tolerability of Brivaracetam in Children and Adolescents With Seizures
Trial Treatment · Phase 3 · UCB Biopharma SRL
Ep0156 237, Durham · Ep0156 259, Hawthorne
Registry updated 2026-07-27
NCT05406349
Neural Mechanisms of Spatial Representations Beyond the Self
Trial Treatment · Boston University Charles River Campus
Boston University, Boston
Registry updated 2026-07-27
NCT06135285
A Device to Prevent Sudden Unexpected Death in Epilepsy: Detecting Peri-Ictal Body Position
Trial Treatment · Brigham and Women's Hospital
Brigham and Women's Hospital, Boston
Registry updated 2026-07-27
NCT07725601
VNS Algorithm for Advanced Dosing
Trial Treatment · Fernando Vale
Wellstar MCG Hospital, Augusta
Registry updated 2026-07-24
NCT01238250
Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight
Research · Simons Searchlight
Boston Children's Hospital, Boston · Geisinger Health System, Lewisburg
Registry updated 2026-07-23
NCT06489561
Neural Computations of Goal-directed Decision-making
Trial Treatment · Cedars-Sinai Medical Center
Cedars-Sinai Medical Center, Los Angeles
Registry updated 2026-07-23
NCT07721272
Human Cognition During Surgery: Stimulation-based and Cholinergic Modulation
Trial Treatment · Early phase 1 · University of Texas Southwestern Medical Center
University of Texas Southwestern Medical Center, Dallas
Registry updated 2026-07-23
NCT07112365
The FINTEPLA as an Anti-SUDEP Therapy in Dravet Syndrome Project
Trial Treatment · Phase 4 · The University of Texas Health Science Center, Houston
The University of Texas Health Science Center at Houston, Houston
Registry updated 2026-07-15
NCT06700356
Thalamus Seizure Detection With a Deep Brain Stimulator System
Trial Treatment · Mayo Clinic
Mayo Clinic in Rochester, Rochester
Registry updated 2026-07-13

All Epilepsy trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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