Frontotemporal dementia: open trials in Spain

• 2025-524480-21-00

  The clinical trial to study a new drug, AP-2.

  Trial Treatment · Phase 1 · Molefy Pharma S.L.

  Hospital Universitario de la Princesa, Madrid

  Registry updated 2026-10-27

• NCT06064890

  A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN)

  Trial Treatment · Phase 1/2 · AviadoBio Ltd

  Hospital Clinic de Barcelona, Barcelona · Hospital Universitario Ramón y Cajal, Madrid · Hospital Universitario Y Politecnico La Fe, Valencia

  Registry updated 2026-08-13

• NCT05741853

  Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia

  Trial Treatment · Stephanie Grasso

  Hospital de la Santa Creu i Sant Pau, Barcelona · Hospital Clinic de Barcelona, Barcelona

  Registry updated 2026-06-10

• NCT07239843

  Prospective Observational Study of the Relationship Between Sociodemographic Factors, Blood-based Biomarkers and Psychiatric Symptoms in Neurodegenerative Diseases and Mental Disorders

  Research · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

  IRSP, Barcelona

  Registry updated 2026-04-24

• NCT07158216

  Long Term Effect of Brain Stimulation in PPA

  Trial Treatment · Hospital San Carlos, Madrid

  Hospital Clínico San Carlos, Madrid

  Registry updated 2026-04-23

• NCT07314190

  Retrospective Observational Study of Blood-based Biomarkers in the Diagnosis and Monitoring of Patients With a Neurodegenerative Disease or Mental Disorder

  Research · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

  Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau - IIB Sant Pau, Barcelona

  Registry updated 2026-02-23

• NCT07234851

  Understanding Mechanisms of Synaptic Degeneration Underlying Clinical Symptoms in Patients With MDs and NDs.

  Research · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

  Research Institute Sant Pau, Barcelona

  Registry updated 2025-12-11

All Frontotemporal dementia trials and the map

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