Glioblastoma trials in Canada

In Canada 18 Also abroad 421

18 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Tamoxifen Versus Etoposide After First Recurrence in GBM Patients
Where
Edmonton
Age
18 years to 65 years
People
60
Run by
AHS Cancer Control Alberta
See details and how to joinNCT04765098
Phase 2/3Taking people
A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma
Where
Montreal, Sherbrooke, Toronto
Age
18 years and over
People
2,250 worldwide
Run by
Global Coalition for Adaptive Research
See details and how to joinNCT03970447 · EU 2024-511452-40-00
Early phase 1Enrolling by invitation
Pilot Trial for Treatment of Recurrent Glioblastoma
Where
Calgary
Age
18 years and over
People
10
Run by
AHS Cancer Control Alberta
See details and how to joinNCT05432518
No phaseTaking people
UNIty-Based MR-Linac Guided Adaptive RadioThErapy for High GraDe Glioma-4
Where
Toronto
Age
18 years and over
People
120
Run by
Sunnybrook Health Sciences Centre
See details and how to joinNCT07459101
Phase 1/2Taking people
A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations
Where
Calgary, Edmonton, Montreal, Ottawa
Age
Up to 25 years
People
75 worldwide
Run by
Turning Point Therapeutics, Inc.
See details and how to joinNCT04094610 · EU 2023-506464-14-00
No phaseTaking people
Targeted Pediatric High-Grade Glioma Therapy
Where
Montreal, Toronto
Age
12 months to 39 years
People
350 worldwide
Run by
Nationwide Children's Hospital
See details and how to joinNCT05839379
Phase 2Taking people
Study of Olutasidenib and Temozolomide in HGG
Where
Montreal, Toronto
Age
12 years to 39 years
People
60 worldwide
Run by
Rigel Pharmaceuticals
See details and how to joinNCT06161974
No phaseTaking people
The Feasibility and Efficacy of Dose Timing (Morning vs Evening) of Temozolomide in the Treatment of Glioblastoma
Where
London, Ottawa
Age
18 years and over
People
50
Run by
Ottawa Hospital Research Institute
See details and how to joinNCT06850766
Early phase 1Taking people
Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion
Where
Montreal, Toronto
Age
1 year to 21 years
People
15 worldwide
Run by
Nationwide Children's Hospital
See details and how to joinNCT06333899
No phaseEnrolling by invitation
The Impact of Resistance ExerciSe on Muscle Mass in GlioblaSToma Survivors
Where
Halifax
Age
18 years and over
People
24
Run by
Nova Scotia Health Authority
See details and how to joinNCT05116137
Phase 2Taking people
Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant
Where
Montreal, Toronto
Age
12 months to 39 years
People
120 worldwide
Run by
Nationwide Children's Hospital
See details and how to joinNCT05843253
Phase 2Taking people
Daily Temozolomide for Elderly Patients With Unmethylated MGMT- Promoter Newly Diagnosed GliOblatoma
Where
Toronto
Age
65 years and over
People
118
Run by
Sunnybrook Health Sciences Centre
See details and how to joinNCT07476794
Phase 1/2Taking people
A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors
Where
Toronto
Age
18 years and over
People
300 worldwide
Run by
LigaChem Biosciences, Inc.
See details and how to joinNCT05941507
Phase 1Taking people
Focused Ultrasound Blood-Brain Barrier Disruption for the Treatment of High-Grade Glioma in Patients Undergoing Standard Chemotherapy
Where
Toronto
Age
18 years to 85 years
People
10
Run by
Sunnybrook Health Sciences Centre
See details and how to joinNCT07179328
Phase 1/2Taking people
IA Carboplatin + Radiotherapy in Relapsing GBM
Where
Sherbrooke
Age
18 years and over
People
35
Run by
Université de Sherbrooke
See details and how to joinNCT03672721
Phase 2Taking people
Intraarterial Carboplatin + Caelyx vs Intraarterial Carboplatin + Etoposide Phosphate for Progressing Glioblastoma
Where
Sherbrooke
Age
18 years and over
People
120
Run by
Université de Sherbrooke
See details and how to joinNCT06356883
Phase 2Taking people
APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
Where
Edmonton, Montreal, Toronto, Winnipeg
Age
18 years and over
People
497 worldwide
Run by
Apollomics Inc.
See details and how to joinNCT03175224 · EU 2024-514542-37-00
No phaseTaking people
THERApeutic Outcomes Related to Gut microBIOME in Glioblastoma (GBM) Patients Receiving Chemo-radiation (THERABIOME-GBM)
Where
Ottawa
Age
18 years and over
People
20
Run by
Ottawa Hospital Research Institute
See details and how to joinNCT05326334