Glioblastoma: open trials in Netherlands

30 open trials have a site in Netherlands. Registry data; only the trial team decides who can take part.

NCT06914128
A Study of PRMT5 Inhibitor BAY 3713372 in Participants With MTAP-deleted Solid Tumors
Trial Treatment · Phase 1/2 · Bayer
Nederlands Kanker Instituut, Amsterdam · Universitair Medisch Centrum Groningen (UMCG) - UMC Groningen Comprehensive Cancer Center, Groningen · Erasmus Medisch Centrum, Rotterdam
Registry updated 2026-10-28
NCT07867886
An Optimization Study Evaluating Safety and Efficacy of the Y-90 Glioblastoma (GBM) Device in Patients With Recurrent GBM
Trial Treatment · Boston Scientific Corporation
University Medical Center Utrecht, Utrecht
Registry updated 2026-10-09
NCT06617208
Pilot IntraOperative Neuronal Electrophysiology in Tumor rElatEd suRgery
Trial Treatment · Erasmus Medical Center
Erasmus MC, Department of Neurosurgery, Rotterdam
Registry updated 2026-10-05
2026-526106-32-00
[¹⁸F]MC225 PET Analysis of Blood–Brain Barrier Function in Glioblastomas
Trial Treatment · Phase 1 · Universitair Medisch Centrum Groningen
UMCG, Groningen
Registry updated 2026-09-28
NCT05839379
Targeted Pediatric High-Grade Glioma Therapy
Research · Nationwide Children's Hospital
Princess Máxima Center, Utrecht
Registry updated 2026-09-08
NCT06161974
Study of Olutasidenib and Temozolomide in HGG
Trial Treatment · Phase 2 · Rigel Pharmaceuticals
Princess Máxima Center, Utrecht
Registry updated 2026-09-01
2025-524555-31-00
A Phase I Study using Oncolytic AdenoVirus Immunotherapy with Repeat Administrations in Recurrent GliOblastoma (VIRAGO)
Trial Treatment · Phase 1 · Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
Amsterdam UMC Stichting, Amsterdam · Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC), Rotterdam
Registry updated 2026-08-21
NCT07100730
Study of TLX101-Tx Plus Standard of Care (SoC) Versus SoC Alone for the Treatment of Patients With Recurrent Glioblastoma
Trial Treatment · Phase 3 · Telix Pharmaceuticals (Innovations) Pty Limited
The Netherlands Cancer Institute (NKI), Amsterdam · UMC Utrecht, Utrecht
Registry updated 2026-08-11
NCT06333899
Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion
Trial Treatment · Early phase 1 · Nationwide Children's Hospital
Princess Máxima Center, Utrecht
Registry updated 2026-06-29
NCT04967690
An open-label dose escalation study to estimate maximum tolerated dose (MTD), identify dose-limiting toxicities (DLTs) and study pharmacokinetics following a single dose of intracranially administered temozolomide-based SI-053 as an add-on to the current standard of care (SoC), in adult patients with newly diagnosed glioblastoma (GBM).
Trial Treatment · Phase 1 · Double Bond Pharmaceutical AB
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC), Rotterdam
Registry updated 2026-06-16
NCT04732065
ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors
Trial Treatment · Phase 1 · Sabine Mueller, MD, PhD
Prinses Maxima Centrum voor Kinderoncologie B.V., Utrecht
Registry updated 2026-06-11
NCT05904119
Lomustine With and Without Reirradiation for First Progression of Glioblastoma: a Randomized Phase III Study
Trial Treatment · Phase 3 · European Organisation for Research and Treatment of Cancer - EORTC
Leiden University Medical Center, Leiden · Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC), Rotterdam · St. Elisabeth Hospital Tilburg, Tilburg
Registry updated 2026-06-08
2023-504696-24-00
The ALPINE trial: a phase 1-2 study of intra-arterial [177Lu]Lu-PSMA-I&T for progressive or recurrent intracranial adult type diffuse glioma
Trial Treatment · Phase 1/2 · Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC), Rotterdam
Registry updated 2026-05-13
2025-522128-28-00
Study Investigating Tucatinib and Osimertinib Pharmacokinetics in Primary and Metastatic Brain Tumors: the STICK trial
Trial Treatment · Phase 1 · Amsterdam UMC Stichting
Amsterdam UMC Stichting, Amsterdam
Registry updated 2026-02-25
NCT02394626
Surgery for Recurrent Glioblastoma
Trial Treatment · Phase 2 · Insel Gruppe AG, University Hospital Bern
Department of Neurosurgery, Amsterdam University Medical Center, Amsterdam · Department of Neurosurgery, Radboud University Medical Center, Nijmegen, Nijmegen · Department of Neurosurgery, Haaglanden Medical Center, The Hague, The Hague
Registry updated 2026-02-02
NCT06645808
PET-imaging of Two Vartumabs in Patients With Solid Tumors
Trial Treatment · Early phase 1 · Var2 Pharmaceuticals
Universitair Medisch Centrum Groningen, Groningen
Registry updated 2025-12-29
NCT07121842
Glioblastoma Imaging for the Detection of Tumor Progression Using APTw-CEST MRI
Trial Treatment · Erasmus Medical Center
Amsterdam UMC, Amsterdam · Leiden UMC, Leiden · Erasmus MC, Rotterdam · UMC Utrecht, Utrecht
Registry updated 2025-08-14
2024-513357-74-01
Phase 0 trial of CBD in recurrent glioblastoma patients
Trial Treatment · Phase 1 · Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC), Rotterdam
Registry updated 2025-07-30
NCT06183983
Hitting the Mark: Introducing State-of-the-art MRI for Precision Radiotherapy of Glioblastoma
Trial Treatment · Erasmus Medical Center
Erasmus Medical Center, Rotterdam
Registry updated 2025-06-12
2024-514013-34-00
Unravelling the invisiBle infiltRating cOmponeNT Of glioblaStomA Using mRi USpio (BRONTOSAURUS)
Trial Treatment · Phase 4 · Stichting Radboud universitair medisch centrum
Radboud universitair medisch centrum Stichting, Nijmegen
Registry updated 2024-12-02
NCT06623565
Extensive Resection of Malignant Brain Tumors Using Advanced Imaging Techniques
Trial Treatment · Amsterdam UMC, location VUmc
Amsterdam UMC location VUmc, Amsterdam
Registry updated 2024-10-02
NCT05929456
MIRROR; Multispectral and bimodal fluorescent guided surgery (FGS) of high-grade glioma for refining margin assessment: A phase 1 dose finding study using Cetuximab-IRDye800CW- combined with 5-ALA
Trial Treatment · Phase 1 · Universitair Medisch Centrum Groningen
UMCG, Groningen
Registry updated 2024-09-03
NCT06480721
FET-PET-Guided Management of Pseudoprogression in Glioblastoma
Trial Treatment · Veerle Ruijters
Amsterdam UMC, Amsterdam · Medisch Spectrum Twente, Enschede · UMC Groningen, Groningen · Maastricht UMC, Maastricht · Radboud UMC, Nijmegen · Erasmus MC, Rotterdam · Haaglanden MC, The Hague · UMC Utrecht, Utrecht
Registry updated 2024-06-28
NCT06283927
The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302)
Research · Jasper Gerritsen
Erasmus MC, Rotterdam · Medical Center Haaglanden, The Hague
Registry updated 2024-02-28
NCT06118723
The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201)
Research · Jasper Gerritsen
Erasmus Medical Center, Rotterdam · Haaglanden Medical Centre, The Hague
Registry updated 2024-02-22

All Glioblastoma trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

Report an error