Glioblastoma trials in United Kingdom

In United Kingdom 20 Also abroad 424

20 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Irinotecan-ChemoSeed in Surgically Resectable Glioblastoma
Where
Birmingham
Age
18 years and over
People
147
Run by
CRISM Therapeutics LTD
See details and how to joinNCT07356973
Phase 1Taking people
Anti-GD2 ADC M3554 in Advanced Solid Tumors
Where
Sutton
Age
18 years and over
People
65 worldwide
Run by
EMD Serono Research & Development Institute, Inc.
See details and how to joinNCT06641908 · EU 2024-513687-26-00
Phase 1/2Taking people
A Study of PRMT5 Inhibitor BAY 3713372 in Participants With MTAP-deleted Solid Tumors
Where
Manchester, Sutton
Age
18 years and over
People
450 worldwide
Run by
Bayer
See details and how to joinNCT06914128 · EU 2025-520623-24-00
Phase 1/2Taking people
Study of an AAV Mediated Dual-Payload Gene Therapy in Patients With High Grade Glioma
Where
Edinburgh
Age
18 years to 70 years
People
68 worldwide
Run by
Trogenix ltd
See details and how to joinNCT07346144
Phase 1/2Taking people
A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations
Where
Birmingham, Cardiff, Glasgow, Liverpool, London
Age
Up to 25 years
People
75 worldwide
Run by
Turning Point Therapeutics, Inc.
See details and how to joinNCT04094610 · EU 2023-506464-14-00
No phaseTaking people
Targeted Pediatric High-Grade Glioma Therapy
Where
London
Age
12 months to 39 years
People
350 worldwide
Run by
Nationwide Children's Hospital
See details and how to joinNCT05839379
No phaseTaking people
Surgery and Laser Interstitial Thermal Therapy for Bilateral Glioblastomas
Where
London
Age
18 years to 80 years
People
12
Run by
King's College Hospital NHS Trust
See details and how to joinNCT07384884
Phase 2Taking people
Study of Olutasidenib and Temozolomide in HGG
Where
London
Age
12 years to 39 years
People
60 worldwide
Run by
Rigel Pharmaceuticals
See details and how to joinNCT06161974
Phase 1Not yet taking people in United Kingdom
Human ADME Study of [14C]-AZD1390
Where
Guildford, Liverpool
Age
18 years to 99 years
People
8
Run by
AstraZeneca
See details and how to joinNCT07643870
No phaseEnrolling by invitation
Triggered Imaging in Glioblastoma Based on Clinical Outcome Evaluation Compared to Routine: a Feasibility Study
Where
London
Age
18 years and over
People
20
Run by
King's College Hospital NHS Trust
See details and how to joinNCT07634575
Phase 2Taking people
Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant
Where
London
Age
12 months to 39 years
People
120 worldwide
Run by
Nationwide Children's Hospital
See details and how to joinNCT05843253
No phaseTaking people
Preoperative Preradiotherapy TTFields
Where
Manchester
Age
35 years and over
People
42
Run by
The Christie NHS Foundation Trust
See details and how to joinNCT06136611
No phaseNot yet taking people in United Kingdom
MRinRT: Swansea University and SWWCC Collaboration Study.
Where
Swansea
Age
18 years and over
People
165
Run by
Swansea Bay University Health Board
See details and how to joinNCT07365124
No phaseNot yet taking people in United Kingdom
FCI-Glioblastoma Study
Where
Aberdeen
Age
18 years to 70 years
People
18
Run by
University of Aberdeen
See details and how to joinNCT07443176
Phase 1Taking people
A Study Assessing if it is Safe and Possible to Treat Brain Cancer Patients With Immunotherapy Before They Receive the Standard Treatment.
Where
London
Age
18 years and over
People
16
Run by
University College, London
See details and how to joinNCT07134842
Phase 1/2Taking people
5G-PEARL: Paxalisib in Malignant Brain Tumours
Where
Sutton
Age
16 years and over
People
64
Run by
Institute of Cancer Research, United Kingdom
See details and how to joinNCT07391215
Phase 1/2Taking people
5G-RUBY: Avutometinib and Defactinib in Malignant Brain Tumours
Where
Cambridge, Sutton
Age
16 years and over
People
182
Run by
Institute of Cancer Research, United Kingdom
See details and how to joinNCT06630260
No phaseTaking people
The CCANED-CIPHER Study: Early Cancer Detection and Treatment Response Monitoring Using AI-Based Platelet and Immune Cell Transcriptomic Profiling
Where
Cambridge, London
Age
40 years to 75 years
People
6,000 worldwide
Run by
Javier Toledo
See details and how to joinNCT06717295
Phase 2Taking people
APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
Where
London, Manchester, Surrey Quays
Age
18 years and over
People
497 worldwide
Run by
Apollomics Inc.
See details and how to joinNCT03175224 · EU 2024-514542-37-00
No phaseTaking people
Ex VIvo DEtermiNed Cancer Therapy
Where
Sheffield
Age
16 years and over
People
600
Run by
Sheffield Teaching Hospitals NHS Foundation Trust
See details and how to joinNCT05231655