Heart failure trials in Australia

In Australia 27 Also abroad 1277

22 of 27 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Where
Adelaide, Brisbane, Chermside, Concord, Frankston, Garran, Gosford, Kingswood, Kotara, Parkville, Perth, Tugun, Woodville
Age
18 years and over
People
6,712 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT06424288 · EU 2023-509706-30-00
No phaseTaking people
ELEVATE-HFpEF Clinical Study
Where
Chermside, Melbourne
Age
40 years and over
People
700 worldwide
Run by
Medtronic Cardiac Rhythm and Heart Failure
See details and how to joinNCT06678841
Phase 3Taking people
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
Where
Auchenflower, Bedford Park, Birtinya, Clayton, Garran, Herston, Joondalup, Leabrook, Liverpool, Melbourne, Milton, Mulgrave, Murdoch, Southport, St Leonards, Woolloongabba
Age
18 years to 99 years
People
5,056 worldwide
Run by
Amgen
See details and how to joinNCT07037459
Phase 3Taking people
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
Where
Adelaide, Castle Hill, Coffs Harbour, Elizabeth Vale, Fremantle, Geelong, Kingswood, Leabrook, Maroubra, Merewether, Milton, Mulgrave, Osborne Park, Rockhampton, Wollongong
Age
40 years and over
People
11,300 worldwide
Run by
AstraZeneca
See details and how to joinNCT06677060 · EU 2024-514506-32-00
Phase 3Taking people
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
Where
Adelaide, Clayton, Darlinghurst, Hobart, Joondalup, Liverpool, Melbourne, Murdoch, Westmead, Woolloongabba
Age
18 years and over
People
1,280 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07207811
Phase 2Taking people
Dose-finding Study of YMI024 to Assess Efficacy, Safety, and Tolerability in Adults With Stable Coronary Artery Disease and Elevated hsCRP
Where
Adelaide, Frankston, Melbourne, Mulgrave
Age
18 years to 80 years
People
180 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07830719 · EU 2026-525974-21-00
No phaseTaking people
A Feasibility Study Implant of the WiSE® CRT System With an Intracardiac Pacemaker to Achieve Totally Leadless CRT
Where
Birtinya, Herston, Southport, Woolloongabba
Age
22 years and over
People
40
Run by
EBR Systems, Inc.
See details and how to joinNCT06561932
Phase 3Taking people
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
Where
Blacktown, Cairns, Canberra, Chermside, Clayton, Concord, Frankston, Geelong, Murdoch, North Tamworth, Westmead
Age
18 years to 130 years
People
3,850 worldwide
Run by
AstraZeneca
See details and how to joinNCT06307652 · EU 2023-508162-15-00
No phaseTaking people
Alleviant ALLAY-HFrEF Study
Where
Clayton, Melbourne
Age
18 years and over
People
350 worldwide
Run by
Alleviant Medical, Inc.
See details and how to joinNCT06812533
No phaseTaking people
Use of Artificial Intelligence-Guided Echocardiography to assIst cardiovascuLar Patient managEment
Where
Alice Springs
Age
45 years and over
People
612
Run by
Baker Heart and Diabetes Institute
See details and how to joinNCT05558605
Phase 3Taking people
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
Where
Blacktown, Campbelltown, Frankston, Hoppers Crossing, North Tamworth, Rockhampton, Wollongong
Age
18 years and over
People
6,950 worldwide
Run by
AstraZeneca
See details and how to joinNCT07761117 · EU 2026-526304-79-00
Phase 3Taking people
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
Where
Adelaide, Blacktown, Elizabeth Vale, Melbourne, Milton, Mulgrave
Age
18 years and over
People
5,200 worldwide
Run by
Colorado Prevention Center
See details and how to joinNCT06008197
Phase 3Taking people
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
Where
Adelaide, Bedford Park, Canberra, Chelmer, Chermside, Elizabeth Vale, Frankston, Geelong, Hobart, Hoppers Crossing, Ipswich, Joondalup, Leabrook, Liverpool, Milton, Mulgrave
Age
18 years and over
People
5,610 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07567001 · EU 2025-523717-29-00
No phaseTaking people
Alleviant ALLAY-HF Study
Where
Clayton, Heidelberg
Age
40 years and over
People
700 worldwide
Run by
Alleviant Medical, Inc.
See details and how to joinNCT05685303
No phaseTaking people
CorWave LVAS FIH Study
Where
Melbourne, Sydney
Age
18 years to 75 years
People
20 worldwide
Run by
CorWave
See details and how to joinNCT06907017
No phaseTaking people
The Early Valve Replacement in Severe ASYmptomatic Aortic Stenosis Study
Where
Adelaide, Chermside, Clayton, Douglas, Elizabeth Vale, Epping, Garran, Geelong, Hobart, Kingswood, Liverpool, New Lambton Heights, Perth, Southport, St Leonards, Tiwi, Westmead, Wollongong
Age
18 years and over
People
2,104 worldwide
Run by
University of Leicester
See details and how to joinNCT04204915
Phase 4Taking people
The STOP-MED CTRCD Trial
Where
Melbourne
Age
18 years and over
People
335 worldwide
Run by
Dinesh Thavendiranathan
See details and how to joinNCT06183437
Phase 2Taking people
A Research Study Comparing CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Reduced/Mildly Reduced Ejection Fraction and Left Ventricular Hypertrophy
Where
Adelaide, Bedford Park, Brisbane, Clayton, Concord, Hobart, Murdoch
Age
40 years to 84 years
People
200 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT06979375 · EU 2024-515797-27-00
No phaseTaking people
Early Atrial Fibrillation Ablation for Stroke Prevention in Patients With High Comorbidity Burden (EASThigh-AFNET 11)
Where
Multiple Locations
Age
18 years and over
People
2,312 worldwide
Run by
Atrial Fibrillation Network
See details and how to joinNCT06324188
No phaseTaking people
Persistent Cardiovascular Effects of COVID-19 Viral Infection Trial (PERCEIVE)
Where
Melbourne
Age
50 years to 85 years
People
820
Run by
Baker Heart and Diabetes Institute
See details and how to joinNCT04983823
No phaseTaking people
Respiratory Sinus Arrhythmia Pacing Post-CABG Surgery in Patients With HFrEF
Where
Adelaide, Melbourne
Age
22 years and over
People
54 worldwide
Run by
Ceryx Medical Australia
See details and how to joinNCT06384963
No phaseTaking people
Risk-guided Disease Management Plan to Prevent Heart Failure in Patients Treated With Previous Chemotherapy (REDEEM)
Where
Melbourne
Age
40 years to 85 years
People
685
Run by
Baker Heart and Diabetes Institute
See details and how to joinNCT04962711