Heart failure trials in Brazil

In Brazil 36 Also abroad 1265

36 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 2/3Taking people
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
Where
São Paulo
Age
29 days to 17 years
People
342 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT05714085 · EU 2022-501238-52-00
Phase 3Taking people
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
Where
Aracaju, Belo Horizonte, Campinas, Curitiba, Goiânia, Marília, Porto Alegre, Ribeirão Preto, Rio de Janeiro, Salvador, Santo André, São José do Rio Preto, São José dos Campos, São Paulo, Tatuí, Vitória
Age
18 years to 99 years
People
5,056 worldwide
Run by
Amgen
See details and how to joinNCT07037459
Phase 3Taking people
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Where
Aracaju, Belo Horizonte, Bragança Paulista, Brasília, Campina Grande do Sul, Campinas, Campo Largo, Curitiba, Goiânia, Marília, Natal, Passo Fundo, Poços de Caldas, Porto Alegre, Recife, Ribeirão Preto, Rio de Janeiro, Rio Do Janeiro, Salvador, Santo André, Sao Jose Rio Preto, São Luís, São Paulo, Uberlândia, Vitória, Votuporanga
Age
18 years and over
People
6,712 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT06424288 · EU 2023-509706-30-00
Phase 3Taking people
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
Where
Bela Vista, Belo Horizonte, Brasília, Campina Grande do Sul, Campinas, Campo Largo, Caxias do Sul, Curitiba, Goiânia, Marília, Minas Gerais, Natal, Passo Fundo, Porto Alegre, Recife, Ribeirão Preto, Rio de Janeiro, Salvador, Santo André, São José do Rio Preto, São José dos Campos, São Paulo, Uberlândia, Vitória
Age
18 years and over
People
4,200 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT06935370 · EU 2024-519525-38-00
Phase 3Taking people
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
Where
Curitiba, Marília, Porto Alegre, Salvador, São Paulo, Uberlândia
Age
Up to 18 years
People
117 worldwide
Run by
Bayer
See details and how to joinNCT07192952 · EU 2024-519830-22-00
Phase 2Taking people
A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)
Where
Belo Horizonte, Botucatu, Brasília, Campinas, Porto Alegre, Ribeirão Preto, São José do Rio Preto, São Paulo
Age
18 years to 79 years
People
620 worldwide
Run by
Pfizer
See details and how to joinNCT06991257 · EU 2024-518438-94-00
Phase 3Taking people
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
Where
Belém, Blumenau, Bragança Paulista, Brasília, Campina Grande do Sul, Campinas, Curitiba, Juiz de Fora, Natal, Porto Alegre, Rio de Janeiro, São José do Rio Preto, São José dos Campos, São Paulo, Tatuí
Age
40 years and over
People
11,300 worldwide
Run by
AstraZeneca
See details and how to joinNCT06677060 · EU 2024-514506-32-00
Phase 3Taking people
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
Where
Belo Horizonte, Brasília, Campinas, Caxias do Sul, Curitiba, Porto Alegre, Recife - PE, Ribeirão Preto, Salvador, São Paulo, Uberlândia
Age
18 years and over
People
1,280 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07207811
No phaseTaking people
The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)
Where
Porto Alegre, São Paulo
Age
18 years and over
People
754 worldwide
Run by
Sunnybrook Health Sciences Centre
See details and how to joinNCT05427370
Phase 3Taking people
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
Where
Curitiba, Marília, Porto Alegre, Salvador, São Paulo, Uberlândia
Age
6 months to 17 years
People
111 worldwide
Run by
Bayer
See details and how to joinNCT07188805 · EU 2024-519829-38-00
Phase 3Taking people
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
Where
Aracaju, Blumenau, Brasília, Campina Grande do Sul, Campinas, Curitiba, Goiânia, Niterói, Porto Alegre, Rio Branco, Rio de Janeiro, São José dos Campos, São Paulo, Teresina, Uberlândia
Age
18 years to 130 years
People
3,850 worldwide
Run by
AstraZeneca
See details and how to joinNCT06307652 · EU 2023-508162-15-00
Phase 3Taking people
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
Where
Aracaju, Belém, Bragança Paulista, Brasília, Campinas, Curitiba, Joinville, Natal, Porto Alegre, Ribeirão Preto, Rio Branco, Rio de Janeiro, São Paulo
Age
18 years and over
People
6,950 worldwide
Run by
AstraZeneca
See details and how to joinNCT07761117 · EU 2026-526304-79-00
No phaseTaking people
Left Bundle Branch Area Pacing (LBBAP) PMCF Study
Where
Rio de Janeiro, São Paulo
Age
18 years and over
People
200 worldwide
Run by
Abbott Medical Devices
See details and how to joinNCT07217392
Phase 3Taking people
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
Where
Aparecida de Goiânia, Aracaju, Arapiraca, Atibaia, Belo Horizonte, Bragança Paulista, Brasília, Campinas, Caxias do Sul, Curitiba, Fortaleza, Goiânia, Itaquera, Joinville, Linhares, Londrina, Natal, Osasco, Passo Fundo, Poços de Caldas, Porto Alegre, Porto Velho, Presidente Prudente, Recife, Rio Branco, Rio de Janeiro, Salvador, Santo André, São Carlos, São José, São José dos Campos, São Paulo, Teresina, Vila Velha, Votuporanga
Age
18 years and over
People
5,200 worldwide
Run by
Colorado Prevention Center
See details and how to joinNCT06008197
Phase 3Taking people
A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)
Where
Aparecida de Goiânia, Aracaju, Arapiraca, Atibaia, Belo Horizonte, Bragança Paulista, Brasília, Campinas, Caxias do Sul, Curitiba, Fortaleza, Goiânia, Itaquera, Joinville, Linhares, Londrina, Natal, Osasco, Passo Fundo, Poços de Caldas, Porto Alegre, Porto Velho, Presidente Prudente, Recife, Rio Branco, Rio de Janeiro, Salvador, Santo André, São Carlos, São José dos Campos, São Paulo, Teresina, Vila Velha, Votuporanga
Age
18 years and over
People
1,500 worldwide
Run by
Colorado Prevention Center
See details and how to joinNCT06024746
No phaseTaking people
iCaReMe Global Registry: Multinational Real-world Evidence in Cardiorenal and Metabolic Diseases
Where
Bragança Paulista, Brasília, Campina Grande do Sul, Colatina, Curitiba, Fortaleza, Goiânia, Joinville, Poços de Caldas, Salvador, Santa Cruz do Sul, São Caetano do Sul, São Paulo, Teresina
Age
18 years and over
People
35,000 worldwide
Run by
AstraZeneca
See details and how to joinNCT03549754
Phase 3Taking people
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
Where
Aracaju, Belo Horizonte, Blumenau, Bragança Paulista, Campinas, Goiânia/GO, Maceió, Marília/SP, Porto Alegre, Recife, Ribeirão Preto, Rio Branco, São Caetano Do Sul / SP, São José dos Campos, Sao Jose Rio Preto, São Paulo, Tatuí, Uberlândia
Age
18 years and over
People
5,610 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07567001 · EU 2025-523717-29-00
No phaseNot yet taking people in Brazil
TELEREHAB-BR: Cardiovascular Rehabilitation Models Trial
Where
Florianópolis
Age
35 years to 80 years
People
219
Run by
University of the State of Santa Catarina
See details and how to joinNCT07734831
No phaseNot yet taking people in Brazil
High-Protein Diet and HMB Supplementation in Patients With Heart Failure
Where
Porto Alegre
Age
18 years and over
People
84
Run by
Hospital de Clinicas de Porto Alegre
See details and how to joinNCT07731048
Phase 3Taking people
A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists
Where
Aparecida de Goiânia, Aracaju, Belo Horizonte, Bragança Paulista, Brasília, Campinas, Caxias do Sul, Curitiba, Fortaleza, Goiânia, Guarulhos, Itaquera, Joinville, Londrina, Maceió, Natal, Osasco, Porto Alegre, Presidente Prudente, Recife, Rio Branco, Rio de Janeiro, Salvador, Santo André, São Carlos, São José dos Campos, São Paulo, Teresina, Votuporanga
Age
18 years and over
People
2,600 worldwide
Run by
Colorado Prevention Center
See details and how to joinNCT06033950
No phaseTaking people
Cardiac Contractility Modulation in Chagas Heart Disease
Where
São Paulo
Age
18 years to 75 years
People
60
Run by
InCor Heart Institute
See details and how to joinNCT05519046
No phaseTaking people
Isolated Resistance Training and Neuromuscular Electrical Stimulation in Patients With Femoral Intra Aortic Balloon Pump.
Where
São Paulo
Age
18 years and over
People
60
Run by
University of Sao Paulo General Hospital
See details and how to joinNCT06316349
No phaseTaking people
Effect of Resistance Training in Patients on the Waiting List for Heart Transplant
Where
São Paulo
Age
18 years to 70 years
People
50
Run by
University of Sao Paulo General Hospital
See details and how to joinNCT06426173
No phaseTaking people
Inspiratory Muscle Training in Hospitalized Heart Failure Patients
Where
Rio de Janeiro
Age
18 years and over
People
30
Run by
CAROLINA NIGRO DI LEONE
See details and how to joinNCT07108231
Phase 3Taking people
Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia
Where
Fortaleza, Porto Alegre, Rio de Janeiro, São Paulo
Age
6 years to 11 years
People
60 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06597019