Heart failure trials in Spain

In Spain 95 Also abroad 1266

77 of 95 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity (MARITIME-HF)
Where
A Coruña, Badalona, Barcelona, Córdoba, Denia, Las Palmas De Gran Canaria, L'hospitalet De Llobregat, Lleida, Madrid, Majadahonda, Málaga, Murcia, Salamanca, Valencia
Age
18 years and over
People
2,787 worldwide
Run by
Amgen Inc.
See details and how to join2024-516654-22-00 · EU 2024-516654-22-00
Phase 2/3Taking people
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
Where
A Coruña, Barcelona, Esplugues de Llobregat, Madrid, Sevilla
Age
29 days to 17 years
People
342 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT05714085 · EU 2022-501238-52-00
No phaseNot yet taking people in Spain
High-Intensity Interval Versus Aerobic Training for Patient-Reported Outcomes in Women With Heart Failure.
Where
Córdoba
Age
18 years and over
People
36
Run by
Universidad Internacional Isabel I de Castilla
See details and how to joinNCT07925515
Phase 4Not yet taking people in Spain
iSGLT2 in permanent atrial fibrillation, heart failure with preserved ejection fraction and intermediate NT-proBNP values: randomized clinical trial
Where
Badalona, Barcelona, Gijón, Reus, Sabadell
Age
65 years and over
People
125
Run by
Institut D Investigacio Sanitaria Pere Virgili
See details and how to join2026-525968-18-00 · EU 2026-525968-18-00
No phaseTaking people
Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects With Reduced Ejection Fraction
Where
Barcelona, Valencia
Age
40 years and over
People
50 worldwide
Run by
Axon Therapies, Inc.
See details and how to joinNCT07403058
Phase 3Not yet taking people in Spain
UNLOAD-CHF Urea for Normalizing hyponatremia and reducing voLume Overload in Acute and Chronic Heart Failure
Where
L'hospitalet De Llobregat, Madrid, Málaga, Sevilla, Vigo, Viladecans
Age
18 years and over
People
210
Run by
Nutricion Medica S.L.
See details and how to join2025-523981-26-03 · EU 2025-523981-26-03
Phase 3Taking people
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
Where
A Coruña, Barcelona, L'hospitalet De Llobregat, Lleida, Lugo, Madrid, Majadahonda, Málaga, Murcia, Salamanca, Santiago de Compostela, Sevilla, Tarragona, Ubeda, Jaen, Valencia, Vigo
Age
18 years to 85 years
People
1,800 worldwide
Run by
Cytokinetics
See details and how to joinNCT06736574 · EU 2024-519219-32-00
No phaseTaking people
Determining Efficacy of an Artificial Intelligence-based System for Heart Failure Detection Through Interpretation of Electrocardiograms (DECISION)
Where
Madrid, Santander
Age
65 years and over
People
1,968 worldwide
Run by
Idoven 1903 S.L.
See details and how to joinNCT07113223
Phase 3Taking people
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
Where
A Coruña, Badalona, Barcelona, Córdoba, Denia, El Palmar, Las Palmas de Gran Canaria, L'Hospitalet de Llobregat, Lleida, Madrid, Majadahonda, Málaga, Salamanca, Valencia
Age
18 years to 99 years
People
5,056 worldwide
Run by
Amgen
See details and how to joinNCT07037459
Phase 3Taking people
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Where
Badalona, Barcelona, L'hospitalet De Llobregat, Madrid, Málaga, Murcia, Sanlúcar de Barrameda, Santiago de Compostela, Valencia, Villamartín
Age
18 years and over
People
6,712 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT06424288 · EU 2023-509706-30-00
Phase 3Taking people
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
Where
Barcelona, Madrid, Málaga, Sanlúcar de Barrameda, Santiago de Compostela, Torrejón de Ardoz, Valencia, Villamartín
Age
18 years and over
People
4,200 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT06935370 · EU 2024-519525-38-00
Phase 3Taking people
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
Where
Barcelona, Córdoba, Esplugues de Llobregat, Madrid, Málaga, Sevilla
Age
Up to 18 years
People
117 worldwide
Run by
Bayer
See details and how to joinNCT07192952 · EU 2024-519830-22-00
Phase 2Taking people
A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)
Where
Barcelona, Córdoba, L'hospitalet De Llobregat, Madrid, Majadahonda, Santiago De Compostela, Valencia
Age
18 years to 79 years
People
620 worldwide
Run by
Pfizer
See details and how to joinNCT06991257 · EU 2024-518438-94-00
Phase 3Taking people
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
Where
A Coruña, Barcelona, Cabra, Córdoba, L'hospitalet De Llobregat, Madrid, Málaga, Santiago de Compostela, Sevilla, Valencia, Vigo
Age
40 years and over
People
11,300 worldwide
Run by
AstraZeneca
See details and how to joinNCT06677060 · EU 2024-514506-32-00
Phase 3Taking people
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
Where
A Coruña, Badalona, Barcelona, Bilbao, Córdoba, Donostia / San Sebastian, Las Palmas de Gran Canaria, L'Hospitalet de Llobregat, Madrid, Majadahonda, Málaga, Palma de Mallorca, Santiago de Compostela, Seville, Úbeda, Valencia, Zaragoza
Age
18 years and over
People
1,280 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07207811
No phaseTaking people
The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)
Where
Alicante, Barcelona, El Palmar, Pamplona
Age
18 years and over
People
754 worldwide
Run by
Sunnybrook Health Sciences Centre
See details and how to joinNCT05427370
Phase 3Taking people
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
Where
Barcelona, Córdoba, Esplugues de Llobregat, Madrid, Málaga, Sevilla
Age
6 months to 17 years
People
111 worldwide
Run by
Bayer
See details and how to joinNCT07188805 · EU 2024-519829-38-00
Phase 3Taking people
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
Where
A Coruña, Barcelona, Lugo, Madrid, Majadahonda, Seville, Valencia
Age
18 years to 130 years
People
3,850 worldwide
Run by
AstraZeneca
See details and how to joinNCT06307652 · EU 2023-508162-15-00
No phaseTaking people
Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)
Where
Barcelona, Madrid, Valencia
Age
22 years and over
People
400 worldwide
Run by
Reprieve Cardiovascular, Inc
See details and how to joinNCT06898515
No phaseTaking people
Alleviant ALLAY-HFrEF Study
Where
A Coruña, Barcelona, Madrid, Salamanca, Valencia
Age
18 years and over
People
350 worldwide
Run by
Alleviant Medical, Inc.
See details and how to joinNCT06812533
Phase 2Taking people
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
Where
Barcelona, Granada, Las Palmas De Gran Canaria, Madrid, Murcia, Valencia
Age
40 years to 84 years
People
200 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT06979362 · EU 2024-515796-35-00
No phaseNot yet taking people in Spain
Remote Monitoring and Optimization of Heart Failure Therapy
Where
Madrid
Age
18 years to 85 years
People
800 worldwide
Run by
Zoll Medical Corporation
See details and how to joinNCT07622472
Phase 4Taking people
Withdrawal of Heart Failure Treatment Patients With Non-ischemic Cardiomyopathy Who Have Been Super-responders to Cardiac Resynchronization Therapy.
Where
Barcelona, Girona, Granada, L'Hospitalet de Llobregat
Age
18 years and over
People
64
Run by
Institut d'Investigació Biomèdica de Bellvitge
See details and how to joinNCT07851779 · EU 2025-521780-12-00
Phase 3Taking people
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
Where
Barcelona, Jaén, Madrid, Murcia, Salamanca, Sanlúcar de Barrameda, Sevilla, Valencia, Villamartín
Age
18 years and over
People
6,950 worldwide
Run by
AstraZeneca
See details and how to joinNCT07761117 · EU 2026-526304-79-00
No phaseTaking people
Left Bundle Branch Area Pacing (LBBAP) PMCF Study
Where
Madrid
Age
18 years and over
People
200 worldwide
Run by
Abbott Medical Devices
See details and how to joinNCT07217392