Heart failure trials in Spain

In Spain 94 Also abroad 1261

94 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 10 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
A Study to Learn About the Use of Acoramidis in Patients With a Heart Condition Called Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in a Real-world Setting
Where
Multiple Locations
Age
18 years and over
People
2,000 worldwide
Run by
Bayer
See details and how to joinNCT07235462
No phaseTaking people
Alleviant ALLAY-HFrEF Study
Where
A Coruña, Barcelona, Madrid, Salamanca, Valencia
Age
18 years and over
People
350 worldwide
Run by
Alleviant Medical, Inc.
See details and how to joinNCT06812533
Phase 2Taking people
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
Where
Barcelona, Granada, Las Palmas De Gran Canaria, Madrid, Murcia, Valencia
Age
40 years to 84 years
People
200 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT06979362 · EU 2024-515796-35-00
No phaseNot yet taking people in Spain
Remote Monitoring and Optimization of Heart Failure Therapy
Where
Madrid
Age
18 years to 85 years
People
800 worldwide
Run by
Zoll Medical Corporation
See details and how to joinNCT07622472
Phase 4Taking people
Withdrawal of Heart Failure Treatment Patients With Non-ischemic Cardiomyopathy Who Have Been Super-responders to Cardiac Resynchronization Therapy.
Where
Barcelona, Girona, Granada, L'Hospitalet de Llobregat
Age
18 years and over
People
64
Run by
Institut d'Investigació Biomèdica de Bellvitge
See details and how to joinNCT07851779 · EU 2025-521780-12-00
No phaseTaking people
Urinary Chloride and Sodium Changes and Residual Congestion in Acute Heart Failure
Where
Madrid, Majadahonda, Olot, Valencia
Age
18 years and over
People
223
Run by
Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
See details and how to joinNCT07597512
Phase 3Taking people
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
Where
Barcelona, Jaén, Madrid, Murcia, Salamanca, Sanlúcar de Barrameda, Sevilla, Valencia, Villamartín
Age
18 years and over
People
6,950 worldwide
Run by
AstraZeneca
See details and how to joinNCT07761117 · EU 2026-526304-79-00
No phaseTaking people
Left Bundle Branch Area Pacing (LBBAP) PMCF Study
Where
Madrid
Age
18 years and over
People
200 worldwide
Run by
Abbott Medical Devices
See details and how to joinNCT07217392
Phase 4Taking people
Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart Failure
Where
Barcelona, Madrid, Seville
Age
18 years to 130 years
People
60 worldwide
Run by
AstraZeneca
See details and how to joinNCT06651970
No phaseTaking people
Genetic Characterization of Patients With Arrhythmia-Induced Cardiomyopathy
Where
Albacete, Ciudad Real, Madrid
Age
18 years and over
People
109
Run by
Hospital Universitario 12 de Octubre
See details and how to joinNCT06896266
Phase 1/2Taking people
A Phase 1b/2a Trial to Evaluate Invobenitug Also Known as Procizumab (PCZ; AK1967) in Critical Cardiovascular Care.
Where
A Coruña, Barcelona, L'hospitalet De Llobregat, Madrid
Age
18 years to 80 years
People
90 worldwide
Run by
4TEEN4 Pharmaceuticals GmbH
See details and how to joinNCT06832722 · EU 2024-518450-16-00
Phase 2Not yet taking people in Spain
A Study to Evaluate the Safety and Efficacy of AC01 Compared to Placebo in Participants With Chronic Heart Failure
Where
A Coruña, Alicante, Castilleja De La Cuesta, Madrid, Palma, Salamanca, Sevilla, Ubeda, Jaen, Valencia
Age
18 years to 85 years
People
400 worldwide
Run by
AnaCardio AB
See details and how to joinNCT07584967 · EU 2025-524469-25-00
Phase 3Taking people
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
Where
A Coruña, Badalona, Barcelona, Girona, Madrid, Manises, Murcia, Pamplona, Sanlúcar de Barrameda, Santiago de Compostela, Valencia, Villamartín, Zaragoza
Age
18 years and over
People
5,200 worldwide
Run by
Colorado Prevention Center
See details and how to joinNCT06008197
Phase 3Taking people
A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)
Where
A Coruña, Barcelona, Madrid, Málaga, Manises, Santiago de Compostela, Valencia
Age
18 years and over
People
1,500 worldwide
Run by
Colorado Prevention Center
See details and how to joinNCT06024746
No phaseTaking people
Retinal Fundus Imaging and OCT Imaging for Ocular Detection of ATTR-CM
Where
L'Hospitalet de Llobregat, Madrid, Palma de Mallorca
Age
18 years and over
People
500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07690436
Phase 2Not yet taking people in Spain
A Phase 2, randomized, double-blind, placebo-controlled trial to evaluate the efficacy, safety, and tolerability of CRD-4730 in patients with heart failure with reduced ejection fraction (HFREF) (CALIBRATE-HF)
Where
Barcelona, Córdoba, L'hospitalet De Llobregat, Murcia, Santiago de Compostela
Age
18 years and over
People
369 worldwide
Run by
Cardurion Pharmaceuticals Inc.
See details and how to join2025-525033-31-00 · EU 2025-525033-31-00
No phaseTaking people
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
Where
Burgos, El Palmar, Madrid, Majadahonda, Málaga, Oviedo, Palma de Mallorca
Age
18 years and over
People
1,700 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT05489705
Phase 3Taking people
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
Where
A Coruna, A Coruña, Alcorcón, Antequera, Badalona, Barcelona, Bilbao, Girona, Granada, Jaén, Las Palmas De Gran Canaria, L'hospitalet De Llobregat, Lugo, Madrid, Majadahonda, Manises, Murcia, Sanlúcar de Barrameda, Sevilla, Valencia, Villamartín
Age
18 years and over
People
5,610 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07567001 · EU 2025-523717-29-00
No phaseTaking people
Alleviant ALLAY-HF Study
Where
Barcelona, Cadiz, Madrid, Salamanca, Valencia
Age
40 years and over
People
700 worldwide
Run by
Alleviant Medical, Inc.
See details and how to joinNCT05685303
No phaseTaking people
Early Detection and IntervenTion in Heart Failure
Where
Madrid
Age
65 years and over
People
18,000 worldwide
Run by
University Hospital, Basel, Switzerland
See details and how to joinNCT07731490
No phaseNot yet taking people in Spain
Exercise-Based Cardiac Rehabilitation for Patients With Heart Failure With Preserved Ejection Fraction (EMPOWER-HFpEF)
Where
Valencia
Age
18 years and over
People
390
Run by
Fundación para la Investigación del Hospital Clínico de Valencia
See details and how to joinNCT07727096
No phaseTaking people
The Early Valve Replacement in Severe ASYmptomatic Aortic Stenosis Study
Where
Barcelona, Pamplona
Age
18 years and over
People
2,104 worldwide
Run by
University of Leicester
See details and how to joinNCT04204915
Phase 3Taking people
A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists
Where
A Coruña, Barcelona, Girona, Madrid, Majadahonda, Málaga, Manises, Santiago de Compostela, Valencia
Age
18 years and over
People
2,600 worldwide
Run by
Colorado Prevention Center
See details and how to joinNCT06033950
Phase 4Taking people
The STOP-MED CTRCD Trial
Where
Madrid
Age
18 years and over
People
335 worldwide
Run by
Dinesh Thavendiranathan
See details and how to joinNCT06183437
No phaseTaking people
Sarcopenia in Older Patients Hospitalized for Acute Heart Failure.
Where
Madrid
Age
80 years and over
People
110
Run by
Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
See details and how to joinNCT07530029