Haemophagocytic lymphohistiocytosis trials in United States

In United States 11 Also abroad 35

11 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Hemophagocytic Lymphohistiocytosis (HLH) Evaluation and Research of Clinical, ImmUnoLogic and TranscriptomE Study
Where
Bethesda, Pittsburgh
Age
18 years to 120 years
People
300
Run by
National Institute of Allergy and Infectious Diseases (NIAID)
See details and how to joinNCT06339177
No phaseNot yet taking people in United States
Long Term Safety Study in Patients With HLH/MAS in Still's Disease Exposed to Gamifant.
Where
Ann Arbor, Atlanta, Birmingham, Boston, Charlotte, Cincinnati, Columbus, Dallas, Houston, Los Angeles, Miami, Minneapolis, New York, Philadelphia, Pittsburgh, Seattle, St. Petersburg
Age
Up to 80 years
People
70
Run by
Swedish Orphan Biovitrum
See details and how to joinNCT07909005
No phaseTaking people
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
Where
Sioux Falls
People
20,000
Run by
Sanford Health
See details and how to joinNCT01793168
Phase 2/3Taking people
Open-label Study of ELA026 in Participants With Secondary Hemophagocytic Lymphohistiocytosis (sHLH)
Where
Atlanta, Birmingham, Cleveland, Dallas, Houston, Los Angeles, New York, Philadelphia, Phoenix, Rockville, Salt Lake City, Seattle, St. Petersburg, Washington D.C.
Age
6 years and over
People
156 worldwide
Run by
Electra Therapeutics Inc.
See details and how to joinNCT05416307
Phase 2Taking people
Ruxolitinib With De-Intensified HLH-94 for the Treatment of Hemophagocytic Lymphohistiocytosis (HLH)
Where
Irvine, Sacramento, San Diego, San Francisco
Age
18 years and over
People
54
Run by
Jerry Lee, MD, MSc, MPhil
See details and how to joinNCT06160791
Phase 1Taking people
Ruxolitinib for Immune Effector Cell Associated Hemophagocytic Lymphohistiocytosis-like Syndrome (RISE)
Where
Baltimore
Age
18 years to 99 years
People
16
Run by
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
See details and how to joinNCT07424222
Phase 2Not yet taking people in United States
Naive T Cell Deplete Grafts for GVHD Prevention in Non-Malignant Diseases
Where
Seattle
Age
6 months to 50 years
People
40
Run by
Fred Hutchinson Cancer Center
See details and how to joinNCT07660783
No phaseTaking people
INTO-HLH: A Disease Registry for Patients With Hemophagocytic Lymphohistiocytosis (HLH)
Where
Cincinnati
People
200
Run by
Children's Hospital Medical Center, Cincinnati
See details and how to joinNCT05277272
No phaseTaking people
Describing Treatment Outcomes and Responses in Lymphoma-associated Hemophagocytic Lymphohistiocytosis
Where
Birmingham
People
2,000
Run by
University of Alabama at Birmingham
See details and how to joinNCT05898477
No phaseTaking people
Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC
Where
Pittsburgh
Age
2 months to 60 years
People
50
Run by
Paul Szabolcs
See details and how to joinNCT04528355
Phase 2Taking people
Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT
Where
Pittsburgh
Age
2 months to 55 years
People
100
Run by
Paul Szabolcs
See details and how to joinNCT01962415