Huntington's disease: open trials in United Kingdom

• NCT07378644

  Study to Evaluate the Pharmacodynamics, Safety and Efficacy of SKY-0515 in Participants With Huntington's Disease

  Trial Treatment · Phase 2/3 · Skyhawk Therapeutics, Inc.

  University College of London, London · Neuroclnx, Motherwell

  Registry updated 2026-11-06

• NCT07609108

  Pridopidine Phase 3 Study in Huntington's Disease

  Trial Treatment · Phase 3 · Prilenia

  NHS Grampian, Aberdeen · Birmingham and Solihull Mental Health Foundation NHS Trust, Birmingham · Cardiff University, Cardiff · The Walton Centre NHS Foundation Trust, Liverpool · CNTW NHS Foundation Trust, Newcastle upon Tyne

  Registry updated 2026-11-04

• NCT07536061

  A First-in-human Study of the Effects of SRP-1005 in Participants With Huntington's Disease

  Trial Treatment · Phase 1 · Sarepta Therapeutics, Inc.

  University Hospital of Wales, Cardiff

  Registry updated 2026-10-19

• NCT06585449

  A Study to Evaluate ALN-HTT02 in Adult Patients With Huntington's Disease

  Trial Treatment · Phase 1 · Alnylam Pharmaceuticals

  Birmingham · Cambridge · Cardiff · Glasgow · Greater Manchester · London · Oxford · Plymouth

  Registry updated 2026-10-15

• NCT07326709

  A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease

  Trial Treatment · Phase 3 · Novartis Pharmaceuticals

  Aberdeen · Cambridge · Cardiff · Exeter · Glasgow · Leeds · University College Hospital, London · London · Oxford · Southampton General Hospital, Southampton

  Registry updated 2026-09-22

• NCT05822908

  A Safety and Pharmacokinetics Trial of VO659 in SCA1, SCA3 and HD

  Trial Treatment · Phase 1/2 · Vico Therapeutics B. V.

  University College London Hospitals NHS Foundation, London · John Radcliffe Hospital, Oxford

  Registry updated 2026-08-19

• NCT02855476

  HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Disease

  Research · University College, London

  Birmingham Huntingtons Disease Clinic, Birmingham · North Bristol NHS Trust, Bristol · Cambridge University Hospitals NHS Foundation Trust, Cambridge · Cardiff University, Cardiff · Royal Devon & Exeter NHS Foundation Trust, Exeter · Glasgow Clinical Research Facility, Glasgow · Fife Health Board - Whyteman's Brae Hospital, Kirkcaldy · Leeds Teaching Hospital Trust, Leeds · The Walton Centre NHS Foundation Trust, Liverpool · University College London Hospitals NHS Foundation Trust, London · St. George's, University of London, London · Oxford University Hospitals NHS Foundation Trust, Oxford · University Hospitals Plymouth NHS Trust, Plymouth

  Registry updated 2026-04-27

• NCT03434548

  IMarkHD: in Vivo Longitudinal Imaging of HD Pathology

  Research · King's College London

  King's College London, London

  Registry updated 2025-03-05

• NCT01574053

  Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

  Research · CHDI Foundation, Inc.

  University of Aberdeen, Aberdeen · Birmingham and Solihull Mental Health NHS Foundation Trust, Birmingham · North Bristol NHS Trust, Bristol · University of Cambridge, Cambridge · Cardiff University, Cardiff · Tayside Health Board, Dundee · Lothian Health Board, Edinburgh · Royal Devon and Exeter NHS Foundation Trust, Exeter · Greater Glasgow Health Board, Glasgow · Ayrshire Central Hospital, Kilmarnock · Fife Health Board, Kirkcaldy · NHS Forth Valley, Larbert · Leeds Teaching Hospitals, Leeds · The Walton Centre, Liverpool · St. George's Hospital, London · Guy's and St Thomas's NHS Foundation Trust, London · University College of London, London · Central Manchester University Hospitals Nhs Foundation Trust, Manchester · Leicestershire Partnership, Narborough · Northumberland, Tyne & Wear NHS Foundation Trust of St. Nicholas Hospital, Newcastle upon Tyne · St. Andrews Healthcare, Northampton · Oxford Radcliffe Hospitals, Oxford · Plymouth Hospitals NHS Trust, Plymouth · Poole Hospital, Poole · Royal Berkshire NHS Foundation Trust, Reading · Sheffield Children's NHS Foundation Trust, Sheffield · University Hospital Southampton, Southampton · North Staffordshire Combined Healthcare NHS Trust, Stoke-on-Trent · Avon and Wiltshire Mental Health Partnership, Swindon · Betsi Cadwaladr University Health Board, Wrexham

  Registry updated 2024-02-28

All Huntington's disease trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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