High blood pressure trials in South Africa

In South Africa 6 Also abroad 843

6 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
Where
Bellville, Benoni, Bloemfontein, Cape Town, Durban, Johannesburg, KwaDukuza, Lenasia, Midrand, Newton, Parow
Age
18 years and over
People
5,000 worldwide
Run by
AstraZeneca
See details and how to joinNCT06742723 · EU 2023-506460-14-00
Phase 3Not yet taking people in South Africa
A Research Study to Investigate How Well the Medicine CagriSema Lowers High Blood Pressure in People Living With High Blood Pressure and Obesity
Where
Durban, eMkhomazi, Gauteng, Johannesburg, Midrand
Age
18 years and over
People
1,408 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07919405
Phase 3Taking people
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Where
Benoni, Bloemfontein, Cape Town, Centurion, Century City, Durban, Gauteng, Johannesburg, Pietermaritzburg, Pretoria, Raslouw, Somerset West, Soweto, Tygervalley, Worcester, Wynberg
Age
18 years and over
People
11,800 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT07064473 · EU 2025-521188-11-00
Phase 3Taking people
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
Where
Belville, Bloemfontein, Cape Town, Chatsworth, City of Johannesburg, Durban, Ekurhuleni, Gauteng, Johannesburg, KwaDukuza, KwaZulu - Natal, Mogale City, Mossel Bay, Nelson Mandela Bay, Plettenberg Bay, Pretoria, Soweto, Worcester
Age
18 years and over
People
11,000 worldwide
Run by
Alnylam Pharmaceuticals
See details and how to joinNCT07181109 · EU 2025-522960-34-00
No phaseTaking people
iCaReMe Global Registry: Multinational Real-world Evidence in Cardiorenal and Metabolic Diseases
Where
Florida, Parow, Umhlanga
Age
18 years and over
People
35,000 worldwide
Run by
AstraZeneca
See details and how to joinNCT03549754
No phaseTaking people
National Blood Pressure Screening in Children to Improve Paediatric Healthcare in South Africa
Where
Bloemfontein, Cape Town, Durban, Johannesburg, Mthatha, Polokwane, Port Elizabeth, Potchefstroom
Age
5 years to 18 years
People
22,464 worldwide
Run by
North-West University, South Africa
See details and how to joinNCT05982847