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IgA nephropathy: open trials in United States

22 open trials have a site in United States. Registry data; only the trial team decides who can take part.

  • NCT06963827

    A Study of Mezagitamab in Adults With Kidney Condition Called IgA Nephropathy

    Trial Treatment · Phase 3 · Takeda

    Renal Medicine Associates - Frenova F1, Albuquerque · Panoramic Health - Virginia Nephrology Group, Arlington · UAB Nephrology Research Clinic at Paula Building, Birmingham · CARE Institute - Boise Kidney, Boise · Northwestern University, Chicago · Panoramic Health - Kidney and Hypertension Center, Cincinnati · Elixia MNA, City of Saint Peters · DCR Columbus, Columbus · Dallas Renal Group, Dallas · Panoramic Health - Southeast Kidney Associates, East Point · Panoramic Health - Nephrology Associates, Inc., East Providence · DCR Edina, Edina · DCR - El Paso, El Paso · Panoramic Health - West Coast Kidney Institute (Fremont), Fremont · Houston Methodist Research Institute - Department of Medicine, Houston · Provecta Research Network, Houston · Panoramic Health - Florida Kidney Physicians, LLC (Jacksonville), Jacksonville · Clinical Research Consultants, a JCCT Company, Kansas City · Nephrology Associates of Houston PLLC, Katy · Ingham Nephrology & Hypertension, P.C., Lansing · South Florida Research Institute, Lauderdale Lakes · UCLA University of California Los Angeles, Los Angeles · Academic Medical Research Institute, Los Angeles · Panoramic Health - Clinical Renal Associates, Ltd., Media · Panoramic Health - Florida Kidney Physicians, LLC (Melbourne), Melbourne · Total Health and Research Center (THRC), Miami · Bioresearch Partners, Miami · DCR Montgomery, Montgomery · West Virginia University, Morgantown · University of California Irvine, Orange · CTR Oakwater, LLC, Orlando · Bioresearch Partners, Pembroke Pines · Thomas Jefferson University, Philadelphia · Elixia MKC, Pontiac · Panoramic Health - Florida Kidney Physicians, LLC (Tampa), Riverview · Panoramic Health - RNA of Rockford, LLC dba Rockford Nephrology Associates, Rockford · Panoramic Health - Lake Michigan Nephrology, PLC, Saint Joseph · Utah Kidney Research Institute, Salt Lake City · DCR San Antonio, San Antonio · Sun Research Institute, San Antonio · Infigo Clinical Research LLC, Sanford · Kaiser Permanente San Francisco Medical Center, San Francisco · Northwest Louisiana Nephrology, Shreveport · Panoramic Health / Southwest Kidney Institute, PLC, Surprise · Brookview Hills Research Associates, LLC, Winston-Salem

    Registry updated 2026-11-04

  • NCT07902817

    A Phase 3 Blinded Study of JADE101 in Participants With Immunoglobulin A Nephropathy

    Trial Treatment · Phase 3 · Jade Biosciences, Inc.

    Arvada · Atlanta · Katy · Lauderdale Lakes

    Registry updated 2026-11-03

  • NCT07541287

    A Study of JADE101 in Participants With Immunoglobulin A Nephropathy

    Trial Treatment · Phase 2 · Jade Biosciences, Inc.

    Arvada · Chula Vista · Denver · Houston · Orlando · Pembroke Pines

    Registry updated 2026-10-30

  • NCT07773727

    A Study to Evaluate the Effect of ARGX-121 on the Change in Proteinuria in Adult Participants With IgAN

    Trial Treatment · Phase 2 · argenx

    Northwest Houston Arthritis Center - Houston, Houston · Prolato Clinical Research Center, Houston · Kidney and Hypertension Specialists- Virginia, Manassas · Bioresearch Partners, Miami · Nephrology Associates of South Miami PA, Miami · BioResearch Partner - Pembroke Pines, Pembroke Pines · Michigan Kidney Consultants, Pontiac · Utah Kidney Research Institute, Salt Lake City · Amicis Research Center - Valencia, Valencia

    Registry updated 2026-10-27

  • NCT07146906

    A Study to Assess the Effects of Zigakibart on IgA Nephropathy.

    Trial Treatment · Phase 2 · Novartis Pharmaceuticals

    American Clinical Trials, Acworth · Colorado Kidney Care Nephrology, Denver · Inter Med Consultants, Edina · Univ Of Iowa Hospitals And Clinics, Iowa City · UC San Francisco Medical Center, San Francisco

    Registry updated 2026-10-21

  • NCT06989359

    Phase 2 Study of ADX-038 in Complement-Mediated Kidney Disease

    Trial Treatment · Phase 2 · ADARx Pharmaceuticals, Inc.

    Columbus · Dakota Dunes · Dallas · Doral · Great Neck · Houston · Iowa City · Miami · Pembroke Pines · Shelby · Shreveport

    Registry updated 2026-10-20

  • NCT07498335

    Study to Assess the Efficacy, Pharmacokinetics, Safety and Tolerability of Atrasentan in Pediatric Patients With Primary IgAN

    Trial Treatment · Phase 3 · Novartis Pharmaceuticals

    Cincinnati Childrens Hospital MC, Cincinnati · University of Tennessee Health Science Center- Le Bonheur Research Center, Memphis · Hackensack Meridian Health, Neptune City · University of Oklahoma Health Science Center, Oklahoma City

    Registry updated 2026-10-15

  • NCT06935357

    A Study to Learn About the Effects of Felzartamab Infusions on Adults With Immunoglobulin A Nephropathy (IgAN)

    Trial Treatment · Phase 3 · Biogen

    American Clinical Trials, LLC., Acworth · Kidney & Hypertension Center - Apple Valley, Apple Valley · The Vasculitis and Glomerulonephritis Center at Massachusetts General Hospital, Boston · Brigham and Women's Hospital, Boston · Nova Clinical Research, LLC, Bradenton · Anointed Nephrology and HTN - SKYCRNG - PPDS, Brookhaven · Scripps Green Hospital, Carlsbad · Midwest Nephrology Associates,Inc., City of Saint Peters · Texas Kidney Institute - Dallas, Dallas · Henry Ford Hospital, Detroit · University of Florida - Gainesville - 1600 SW Archer Rd, Gainesville · National Institute of clinical Research Administration Office, Garden Grove · Royal Research, Corp, Hollywood · Provecta Research Network, Houston · R & H Clinical Research, Katy · Knoxville Kidney Center PLLC, Knoxville · Applied Research Center of Arkansas, Little Rock · UCLA Health David Geffen School of Medicine, Los Angeles · Medical College of Wisconsin, Inc, Milwaukee · Icahn School of Medicine at Mount Sinai, New York · Central Florida Kidney Specialists, Orlando · FOMAT Medical Research - FOMAT - PPDS, Oxnard · Penn Renal Electrolyte and Hypertension Perelman, Philadelphia · Elixia Health - Michigan Kidney Consultants, LLC - Elixia - PPDS, Pontiac · CDC Research Institute LLC, Port Saint Lucie · Lifespan at Rhode Island Hospital, Providence · North America Research Institute - San Dimas, San Dimas · James J Peters Veterans Administration Medical Center - NAVREF - PPDS, The Bronx · Umass Memorial Medical Center, Worcester

    Registry updated 2026-10-14

  • NCT06676579

    Avacopan in Crescentic Immunoglobulin A Nephropathy (IgAN)

    Trial Treatment · Phase 2 · Mayo Clinic

    Mayo Clinic in Florida, Jacksonville · Mayo Clinic in Rochester, Rochester

    Registry updated 2026-10-09

  • NCT04557462

    A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy

    Trial Treatment · Phase 3 · Novartis Pharmaceuticals

    University of Colorado Anschutz, Aurora · Johns Hopkins Hospital, Baltimore · Brigham and Womens Hosp Harvard Med School, Boston · CaRe Research, Chubbuck · Dallas Renal Group, Dallas · AZ Kidney Dise and Hypertension Ctr, Glendale · Nep Assoc of Northern Illinois, Hinsdale · Prolato Clinical Research Center, Houston · New Jersey Kidney Care, Jersey City · Clin Rsrch Consult a JCCT Company, Kansas City · DaVita Clinical Research, Las Vegas · Nephrology Associates PA, Newark · Col Uni Med Center New York Presby, New York · Mayo Clinic - Rochester, Rochester · Kaiser Permanente, San Diego · North America Research Institute, San Dimas

    Registry updated 2026-10-05

  • NCT06419205

    A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G

    Trial Treatment · Phase 2 · Akebia Therapeutics

    Hollywood · Lawrenceville · Orangeburg

    Registry updated 2026-10-01

  • NCT07820995

    Mechanistic Evaluation of Atrasentan in Patients With IgA Nephropathy (IgAN)

    Trial Treatment · Phase 4 · University of Illinois Chicago

    University of Illinois Chicago, Chicago

    Registry updated 2026-09-21

  • NCT06994845

    Study to Assess the Efficacy, Pharmacokinetics, Safety and Tolerability of Iptacopan in Pediatric Patients With Primary IgAN

    Trial Treatment · Phase 3 · Novartis Pharmaceuticals

    Childrens Hospital Colorado, Aurora · Univ of Florida Shands Division, Gainesville · Valley Childrens Hospital, Madera · Childrens Hospital of Philadelphia, Philadelphia · Prim Childrens Hosp Inv Pharm, Salt Lake City

    Registry updated 2026-09-09

  • NCT07182227

    PS-002 for the Treatment of IgA Nephropathy in Adults

    Trial Treatment · Phase 1/2 · Purespring Therapeutics Limited

    The Johns Hopkins Hospital, Baltimore · University of Miami Hospital, Miami

    Registry updated 2026-09-09

  • NCT06858319

    Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy.

    Trial Treatment · Phase 3 · Novartis Pharmaceuticals

    Knoxville Kidney Center Pllc, Brentwood · NY Nephrology, Clifton Park · Dallas Renal Group, Dallas · Colorado Kidney Care Nephrology, Denver · Nephro Asso North Illinois Indiana, Houston · University of Iowa Hospitals and Clinics, Iowa City · Icahn School of Medicine at Mount Sinai, New York · Nephrology Associates Of Central FL, Orlando

    Registry updated 2026-08-17

  • NCT07024563

    Study of Ravulizumab in Pediatric Participants With Primary IgAN

    Trial Treatment · Phase 3 · Alexion Pharmaceuticals, Inc.

    Aurora · Palo Alto

    Registry updated 2026-07-30

  • NCT06797518

    Study to Evaluate the Impact of Iptacopan on Top of SOC on Biopsy Changes in Kidneys of Adult Patients With IgAN

    Trial Treatment · Phase 2 · Novartis Pharmaceuticals

    University of Alabama at Birmingham, Birmingham · CaRe Research, Chubbuck · University Hospitals Cleveland Medical Center*, Cleveland · OSU Wexner Medical Center, Columbus · Prolato Clinical Research Center, Houston · DaVita Clinical Research, Las Vegas · Georgia Nephrology Research Inst, Lawrenceville · UCLA Medical Center, Los Angeles · Central Florida Kidney Specialists, Orlando

    Registry updated 2026-07-29

  • NCT06983028

    Atacicept in Multiple Glomerular Diseases

    Trial Treatment · Phase 2 · Vera Therapeutics, Inc.

    Vera Therapeutics, Brisbane

    Registry updated 2026-06-26

  • NCT07054684

    Study of BHV-1400 in IgA Nephropathy

    Trial Treatment · Phase 1 · Biohaven Therapeutics Ltd.

    Chesterfield · Dakota Dunes · Farmington · Hinsdale · Houston · Houston · Indianapolis · Lawrenceville · Miami Lakes · Miami Lakes · Orlando · Pembroke Pines · Salt Lake City · Shelby

    Registry updated 2026-06-23

  • NCT06674577

    A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Atacicept

    Trial Treatment · Phase 2 · Vera Therapeutics, Inc.

    Vera Therapeutics, Brisbane

    Registry updated 2026-06-22

  • NCT05003986

    Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases

    Trial Treatment · Phase 2 · Travere Therapeutics, Inc.

    C S Mott Children's Hospital, Ann Arbor · Floating Hospital for Children at Tufts Medical Center, Boston · University of North Carolina at Chapel Hill, Chapel Hill · Atrium Health/Levine Children's Hospital, Charlotte · Nationwide Children's Hospital, Columbus · Duke Molecular Physiology Institute, Durham · Hackensack University Medical Center, Hackensack · UT Health - John P. and Kathrine G. McGovern Medical School, Houston · Texas Children's Hospital, Houston · University of Iowa Stead Family Children's Hospital, Iowa City · Children's Mercy Hospitals and Clinics, Kansas City · Cedars-Sinai Medical Center, Los Angeles · Nicklaus Children's Hospital, Miami · University of Miami, Leonard M. Miller School of Medicine, Miami · University of Minnesota/Masonic Children's Hospital, Minneapolis · Jersey Shore University Medical Center, Neptune City · Cohen Children's Medical Center, New Hyde Park · Fink Children's Ambulatory Care Center, New York · University of Oklahoma Health Sciences Center (OUHSC), Oklahoma City · St. Christopher's Hospital for Children, Philadelphia · Children's Hospital of Philadelphia, Philadelphia · Seattle Children's Hospital, Seattle · Nemours Children's Hospital, Wilmington

    Registry updated 2026-05-12

  • NCT01802034

    Registry updated 2025-04-04

All IgA nephropathy trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

IgA nephropathy trials in United States – Frontlight Research