Keratoconus trials in United States

In United States 23 Also abroad 44

23 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
UNITY DX Cornea Study
Where
Salt Lake City
Age
22 years and over
People
110
Run by
Alcon Research
See details and how to joinNCT07768735
No phaseTaking people
A Study to Test the Diagnostic Potential of Brillouin Microscopy for Corneal Ectasia
Where
Boston
Age
20 years to 75 years
People
168
Run by
Massachusetts General Hospital
See details and how to joinNCT02118922
No phaseEnrolling by invitation
Corneal Biomechanical Analysis Using Brillouin Microscopy
Where
Cleveland
Age
18 years to 60 years
People
220
Run by
The Cleveland Clinic
See details and how to joinNCT04598932
Phase 2/3Taking people
Corneal Crosslinking for Treatment of Progressive Keratoconus or Corneal Ectasia
Where
Indianapolis
Age
10 years to 90 years
People
500
Run by
Price Vision Group
See details and how to joinNCT07841470
Phase 1/2Enrolling by invitation
Dextenza Versus Topical Steroid Eye Drops for Postoperative Management Following Corneal Crosslinking
Where
San Francisco
Age
13 years to 64 years
People
20
Run by
Maanasa Indaram, MD
See details and how to joinNCT06235567
No phaseTaking people
A Study to Assess Brillouin Hydration Mapping for the Evaluation of Ocular Tissues and Diseases
Where
Boston
Age
20 years to 79 years
People
90
Run by
Massachusetts General Hospital
See details and how to joinNCT07780890
Phase 4Taking people
Evaluate the Safety and Feasibility of Same-Day Bilateral Epithelium-On Corneal Cross-Linking for Keratoconus
Where
Westerville
Age
13 years and over
People
15
Run by
Glaukos Corporation
See details and how to joinNCT07629557
No phaseTaking people
Corneal Elastography and Patient Specific Modeling
Where
Cleveland
Age
16 years to 80 years
People
60
Run by
The Cleveland Clinic
See details and how to joinNCT03030755
Phase 4Not yet taking people in United States
Outcomes of CTAK Surgery
Where
Palo Alto
Age
18 years to 85 years
People
100
Run by
Stanford University
See details and how to joinNCT07474870
No phaseTaking people
Intacs Prescription Inserts for Keratoconus Patients
Where
Dallas
Age
18 years and over
People
25
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT02138669
No phaseNot yet taking people in United States
A Randomized Clinical Trial of Ex Vivo Corneal Cross-Linking of Donor Keratoplasty Tissue for Keratoconus Used for Keratoplasty in Keratoconus Patients
Where
Boston
Age
18 years to 50 years
People
216
Run by
Joseph B. Ciolino, MD
See details and how to joinNCT04584125
Phase 2Taking people
Placebo-controlled Study to Evaluate the Safety and Efficacy of GLK-221 Ophthalmic Solution in Subjects With Keratoconus
Where
Westerville
Age
18 years to 55 years
People
100
Run by
Glaukos Corporation
See details and how to joinNCT07400952
Phase 3Taking people
Comparison of Epi-ON Corneal Collagen Crosslinking Performed Using an 18-Minute UVA Exposure vs. a 24-Minute UVA Exposure on Eyes With Ectatic Corneal Diseases
Where
Asheville, Atlanta, Canton, Chattanooga, Cumming, Douglasville, Johnson City, Knoxville, Lawrenceville, Marietta, Snellville
Age
8 years and over
People
485
Run by
Woolfson Eye Institute
See details and how to joinNCT07124910
Phase 3Taking people
Compassionate Use Study of Epi-ON Corneal Collagen Crosslinking Performed Using UVA Exposure on Eyes With Ectatic Corneal Diseases for Subjects With Down Syndrome
Where
Asheville, Atlanta, Canton, Chattanooga, Cumming, Douglasville, Johnson City, Knoxville, Lawrenceville, Marietta, Snellville
Age
8 years and over
People
225
Run by
Woolfson Eye Institute
See details and how to joinNCT07135167
No phaseTaking people
fMRI and IVCM Cornea Microscopy of CXL in Keratoconus
Where
Boston
Age
8 years to 35 years
People
60
Run by
Boston Children's Hospital
See details and how to joinNCT04439552
Phase 2Taking people
Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Cross-Linking in Eyes With Corneal Ectasia
Where
San Francisco
Age
10 years and over
People
500
Run by
Goodman Eye Center
See details and how to joinNCT04094090
No phaseTaking people
OCT in Diagnosis of Irregular Corneas
Where
Portland
Age
14 years to 85 years
People
445
Run by
Oregon Health and Science University
See details and how to joinNCT03504800
No phaseTaking people
Collagen Cross-linking in Keratoconus
Where
Portland
Age
18 years and over
People
100
Run by
Oregon Health and Science University
See details and how to joinNCT03760432
No phaseTaking people
Scleral Lens Fitting Using Wide-Field OCT
Where
Portland
Age
18 years and over
People
258
Run by
Oregon Health and Science University
See details and how to joinNCT04570020
No phaseTaking people
The K-Map Study, Global Prevalence of KC
Where
Los Angeles
Age
6 years to 23 years
People
20,000 worldwide
Run by
University Hospital, Geneva
See details and how to joinNCT03115710
Phase 1Taking people
Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Cross-Linking
Where
Eugene
Age
12 years to 45 years
People
300
Run by
Pacific Clear Vision Institute
See details and how to joinNCT03918408
Phase 2Taking people
Safety and Effectiveness of the PXL-Platinum 330 System for Cornea Crosslinking in Eyes With Cornea Thinning
Where
Boca Raton
Age
18 years and over
People
300
Run by
Cohen Laser and Vision Center
See details and how to joinNCT05516004
No phaseNot yet taking people in United States
Assessing Patient Engagement in Keratoconus Clinical Research
Where
San Francisco
Age
18 years and over
People
500
Run by
Power Life Sciences Inc.
See details and how to joinNCT06288737