Kidney cancer trials in Italy

In Italy 48 Also abroad 485

48 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Clinical Study of Belzutifan (MK-6482) and Zanzalintinib in People With Renal Cell Carcinoma (RCC) (LITESPARK-034/LS-034/MK-6482-034)
Where
Bari, Bologna, Florence, Meldola, Milan, Padova, Perugia, Rome, Rozzano
Age
18 years and over
People
758 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT07489495 · EU 2024-516993-31-00
No phaseNot yet taking people in Italy
A Study Comparing Single-Port and Multi-Port Robot-Assisted Surgery in Patients With Prostate or Kidney (Renal) Cancer
Where
Milan
Age
18 years and over
People
376
Run by
IRCCS San Raffaele
See details and how to joinNCT07610083
Phase 3Taking people
Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma
Where
Bari, Florence, Genoa, Lecce, Macerata, Milan, Naples, Padova, Parma, Perugia, Pisa, Rome, Rozzano, Terni, Turin, Verona
Age
18 years and over
People
720 worldwide
Run by
Arcus Biosciences, Inc.
See details and how to joinNCT07011719 · EU 2024-515023-11-00
No phaseNot yet taking people in Italy
Assessment of Intelligent Algorithms for Detection, Diagnosis and Risk Stratification of Tumors of the Kidney and Prostate
Where
Naples
People
50 worldwide
Run by
Aristotle University Of Thessaloniki
See details and how to joinNCT07888322
No phaseTaking people
Stereotactic Body RadioTherapy With Continuous Tracking for Primary and Secondary Renal Cancer
Where
Milan
Age
18 years and over
People
60
Run by
IRCCS San Raffaele
See details and how to joinNCT07285538
Phase 1/2Taking people
A Study to Evaluate the Safety, Tolerability, and Efficacy of Pumitamig Alone or in Combination With Other Agents in Participants With Advanced Renal Cell Carcinoma (RCC) (ROSETTA RCC-208)
Where
Milan, Naples, Verona
Age
18 years and over
People
474 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT07293351 · EU 2026-527163-15-00
Phase 1Taking people
KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors
Where
Bologna, Candiolo, Naples, Rozzano, Verona
Age
18 years and over
People
300 worldwide
Run by
Kura Oncology, Inc.
See details and how to joinNCT06026410 · EU 2024-513285-19-00
Phase 1Taking people
A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies
Where
Bologna, Milan, Rome, Verona
Age
18 years and over
People
280 worldwide
Run by
Incyte Corporation
See details and how to joinNCT07195916 · EU 2025-523130-11-00
Phase 1Taking people
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
Where
Ancona, Bologna, Florence, Milan, Naples, Ravenna
Age
18 years and over
People
1,394 worldwide
Run by
Exelixis
See details and how to joinNCT05176483 · EU 2023-510061-10-00
Phase 1Not yet taking people in Italy
A Study to Assess the Safety and Tolerability of BMS-986527 in Participants With Clear Cell Renal Cell Carcinoma (ccRCC)
Where
Roma, Rozzano
Age
18 years and over
People
112 worldwide
Run by
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
See details and how to joinNCT07848295
Phase 3Taking people
CARE1: FIRST LINE RANDOMISED STUDY PLATFORM TO OPTIMIZE TREATMENT IN PATIENTS WITH METASTATIC RENAL CELL CARCINOMA
Where
Aviano, Bari, Bologna, Brescia, Cremona, Florence, Genoa, Milan, Modena, Naples, Padova, Parma, Pavia, Reggio Emilia, Rome, Terni, Verona
Age
18 years and over
People
1,373 worldwide
Run by
Institut Gustave Roussy
See details and how to join2023-503317-29-00 · EU 2023-503317-29-00
Phase 2Not yet taking people in Italy
Activity of Pembrolizumab plus Enfortumab Vedotin in Collecting Duct and Renal Medullary Carcinoma (REPRINT MeetURO trial)
Where
Milan
Age
18 years and over
People
23
Run by
Fondazione IRCCS Istituto Nazionale Dei Tumori
See details and how to join2024-511587-93-00 · EU 2024-511587-93-00
No phaseTaking people
Microwave Ablation for Treatment of Small Renal Tumors and Primary and Secondary Liver Neoplasms
Where
Milan
Age
18 years and over
People
500
Run by
Francesco De Cobelli
See details and how to joinNCT03981497
No phaseTaking people
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Where
Meldola, Reggio Emilia, Roma
Age
18 years and over
People
2,285 worldwide
Run by
Guardant Health, Inc.
See details and how to joinNCT05059444
No phaseTaking people
Intensified Monitoring of PhArmacology of Cabozantinib as a Tool for Toxicity Management in Patients With Renal Cell Carcinoma
Where
Aviano
Age
18 years and over
People
216
Run by
Centro di Riferimento Oncologico - Aviano
See details and how to joinNCT07805122
Phase 3Not yet taking people in Italy
Sequence Strategy of Immuneoncology (IO-IO) vs IO-tyrosine kinase inhibitors (TKI) followed by TKI in metastatic renal cell carcinoma (mRCC): A randomized phase 3 study Meet uro and FICOG trial. COMBO-Seq trial.
Where
Alba, Arezzo, Aviano, Bari, Carpi, Cremona, Florence, Latina, Lecce, Legnano, Meldola, Milan, Modena, Naples, Novara, Orbassano, Padova, Palermo, Parma, San Giovanni Rotondo, Turin, Varese
Age
18 years and over
People
500
Run by
Fondazione IRCCS Istituto Nazionale Dei Tumori
See details and how to join2025-523903-31-00 · EU 2025-523903-31-00
Phase 1/2Taking people
A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors
Where
Candiolo, Milan, Naples, Roma, Rozzano, Siena
Age
18 years and over
People
1,109 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT04895709
Phase 1Taking people
A First-in-Human Study of BMS-986506 in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC)
Where
Rome, Verona
Age
18 years and over
People
281 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT07195682 · EU 2025-522543-18-00
Phase 3Taking people
A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)
Where
Arezzo, Bari, Bologna, Florence, Genoa, Milan, Naples, Orbassano, Padova, Parma, Peschiera del Garda, Rome, Rozzano
Age
18 years and over
People
904 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT07227402 · EU 2024-517136-21-00
No phaseTaking people
Role of TTV During First-line Immunotherapy Treatment in Patients With Renal Cell Carcinoma
Where
Rome
Age
18 years and over
People
20
Run by
Regina Elena Cancer Institute
See details and how to joinNCT07018037
Phase 4Taking people
Intensified Monitoring of PhArmacology of Cabozantinib as a tool for Toxicity management in patients with renal cell carcinoma
Where
Aviano, Bolzano
Age
18 years and over
People
216
Run by
Centro Di Riferimento Oncologico Di Aviano
See details and how to join2026-525267-40-00 · EU 2026-525267-40-00
Phase 2Taking people
Phase 2 Study for the Patient, Who Has Diagnosed With Small Cell Lung Cancer (SCLC) or Non Small Cell Lung Cancer (NSCLC) or Renal Cell Carcinoma (RCC) and Finished the First Line Stand Treatment , Need More Treatment
Where
Milan, Padova, Rome
Age
18 years and over
People
80 worldwide
Run by
Advenchen Pharmaceuticals, LLC.
See details and how to joinNCT05363280 · EU 2023-509067-24-01
Phase 1Not yet taking people in Italy
A Phase I Study to Evaluate the Safety and Efficacy of L19IL2 in Combination With Ruxolitinib in Patients With Advanced Solid Tumors
Where
Rome
Age
18 years to 75 years
People
96
Run by
Philogen S.p.A.
See details and how to joinNCT07566897 · EU 2025-522243-17-00
Phase 1/2Taking people
A First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their Body
Where
Milan, Naples, Rome, Verona
Age
18 years and over
People
240 worldwide
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT06413680 · EU 2025-523399-22-00
No phaseTaking people
Targeted Decision Making In Renal Cell Carcinoma Relying on a Radiogenomics Translational Platform
Where
Milan
Age
18 years and over
People
50
Run by
IRCCS San Raffaele
See details and how to joinNCT06868927