Lung cancer trials in Canada

In Canada 156 Also abroad 2733

156 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Liquid Biopsy Evaluation and Repository Development at Princess Margaret
Where
Toronto
Age
18 years and over
People
2,500
Run by
University Health Network, Toronto
See details and how to joinNCT03702309
Phase 3Taking people
This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.
Where
Abbotsford British Columbia, Montreal, Saint-Jérôme
Age
18 years and over
People
714 worldwide
Run by
Pfizer
See details and how to joinNCT06758401 · EU 2024-517968-36-00
Phase 3Taking people
A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line Treatment of PD-L1-high Metastatic Non-small Cell Lung Cancer
Where
Cambridge, Edmonton, Kelowna, Newmarket, Québec, Saint-Jérôme, Toronto
Age
18 years and over
People
830 worldwide
Run by
AstraZeneca
See details and how to joinNCT06868277 · EU 2024-517780-24-00
Phase 1/2Taking people
A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)
Where
Edmonton, Toronto
Age
12 years and over
People
359 worldwide
Run by
Nuvalent Inc.
See details and how to joinNCT05118789 · EU 2024-511793-71-00
No phaseTaking people
A Registry for People With Lung Cancer
Where
Montreal, Toronto
Age
18 years and over
People
600 worldwide
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT06424327
Phase 2Taking people
An Adjuvant Study to Evaluate SMS001 (Paclitaxel) in Non-Small Cell Lung Cancer
Where
Toronto
Age
18 years to 80 years
People
42 worldwide
Run by
ToLymph Inc.
See details and how to joinNCT06693336
Phase 1/2Taking people
A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors
Where
Edmonton, Montreal, Newmarket, Ottawa
Age
18 years and over
People
416 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT06618287
Phase 1Taking people
Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors
Where
Montreal
Age
18 years to 100 years
People
116 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07006727 · EU 2024-519111-34-00
Phase 3Taking people
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1
Where
Edmonton, Etobicoke, London, Montreal
Age
18 years and over
People
780 worldwide
Run by
Summit Therapeutics
See details and how to joinNCT06767514 · EU 2024-518629-14-00
Phase 2Taking people
Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible Sensitivity
Where
Toronto, Vancouver
Age
18 years and over
People
50
Run by
British Columbia Cancer Agency
See details and how to joinNCT04273061
No phaseTaking people
An Evaluation of Dose-escalation for Intrathoracic Tumours
Where
Kelowna, London, Saint John, Waterloo
Age
18 years and over
People
141
Run by
Chris Goodman
See details and how to joinNCT06794125
Phase 1/2Taking people
First in Human Study of TUB-030 in Patients With Advanced Solid Tumors
Where
Toronto
Age
18 years and over
People
250 worldwide
Run by
Gilead Sciences
See details and how to joinNCT06657222 · EU 2025-522517-35-00
No phaseTaking people
Non-ablative Oligofractionated Radiation Therapy Before Surgical Transplantation As Radiovaccination
Where
Toronto
Age
18 years and over
People
30
Run by
Marc de Perrot
See details and how to joinNCT04782752
Phase 1Taking people
Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer
Where
Edmonton, Hamilton, Montreal, Toronto
Age
18 years and over
People
350 worldwide
Run by
TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)
See details and how to joinNCT06343402
No phaseTaking people
LUNG-ROLL: Treatment Patterns and Cost of Illness of Lung Cancer in Canada
Where
Calgary, Toronto
Age
18 years to 130 years
People
60,000
Run by
AstraZeneca
See details and how to joinNCT07143110
Phase 1/2Taking people
Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and in Patients With Other Advanced Solid Tumors
Where
Montreal, Toronto
Age
18 years to 100 years
People
280 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06726148 · EU 2024-517281-42-00
Phase 2Taking people
Reducing Respiratory Symptoms of Pulmonary Irradiation in Interstitial Lung Disease
Where
London, Montreal, Saint John, Vancouver
Age
18 years and over
People
98
Run by
David Palma
See details and how to joinNCT05986318
Phase 3Taking people
Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer
Where
Edmonton, Montreal
Age
18 years and over
People
582 worldwide
Run by
AstraZeneca
See details and how to joinNCT06350097 · EU 2023-509883-89-00
Phase 3Taking people
Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma
Where
Calgary, Edmonton, Halifax, Montreal, Sherbrooke
Age
Up to 50 years
People
62 worldwide
Run by
Children's Oncology Group
See details and how to joinNCT05235165
Phase 1Taking people
Pulse Radiotherapy to Overcome Metastatic Immune System Evasion in Lung Cancer
Where
Montreal
Age
18 years and over
People
32
Run by
Centre hospitalier de l'Université de Montréal (CHUM)
See details and how to joinNCT06622174
No phaseTaking people
Study of High-Precision Evaluation of Molecular ResiduaL Disease Through a PlatfOrm for Cancer TracKing and Interception (SHERLOCK)
Where
Toronto
Age
18 years and over
People
7,000
Run by
University Health Network, Toronto
See details and how to joinNCT07524114
Phase 1Taking people
A Study to Assess the Adverse Events, Change in Disease Activity, and How Oral ABBV-711 Tablets Move Through the Body as a Monotherapy and in Combination With Intravenously Infused Budigalimab (ABBV-181), in Adults With Advanced Squamous Tumors
Where
Montreal, Toronto
Age
18 years and over
People
220 worldwide
Run by
AbbVie
See details and how to joinNCT07241039 · EU 2025-521607-48-00
Phase 1/2Taking people
A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors
Where
Edmonton, Hamilton, Montreal, Ottawa, Toronto, Vancouver
Age
18 years and over
People
1,109 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT04895709
Phase 3Taking people
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
Where
Ottawa
Age
18 years and over
People
474 worldwide
Run by
NRG Oncology
See details and how to joinNCT05624996
No phaseTaking people
Study of Neoadjuvant Cemiplimab and Dupilumab in Early-Stage Non-Small Cell Lung Cancer
Where
Montreal
Age
18 years and over
People
24
Run by
Centre hospitalier de l'Université de Montréal (CHUM)
See details and how to joinNCT06743581