Lung cancer trials in Canada

In Canada 156 Also abroad 2733

156 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 1Not yet taking people in Canada
Surgery After Verifying Existing Disease in Locally Advanced Operable Lung Cancer: A Pilot Study
Where
Montreal
Age
18 years and over
People
14
Run by
Centre hospitalier de l'Université de Montréal (CHUM)
See details and how to joinNCT06743555
Phase 2Taking people
Post-operative Radiotherapy After Neodjuvant Chemo-immunotherapy and Surgery in Stage III NSCLC
Where
Montreal
Age
18 years and over
People
118
Run by
Centre hospitalier de l'Université de Montréal (CHUM)
See details and how to joinNCT06878274
Phase 1/2Taking people
A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
Where
Toronto
Age
18 years and over
People
366 worldwide
Run by
Marengo Therapeutics, Inc.
See details and how to joinNCT05592626 · EU 2023-505334-10-01
Phase 3Taking people
A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer
Where
Brampton, Edmonton, Québec, Toronto, Winnipeg
Age
18 years and over
People
540 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06203210 · EU 2023-509628-16-00
Phase 2Taking people
Pneumonitis Prevention Protocol Using Pentoxifylline and α-tocopherol In Stage III Non-Small Cell Lung Cancer Patients Undergoing Chemoradiation
Where
Toronto
Age
18 years and over
People
150
Run by
University Health Network, Toronto
See details and how to joinNCT06634056
No phaseTaking people
The Development, Safety, and Feasibility of an Artificial Intelligence-Powered Platform (NodeAI) for Real-Time Prediction of Mediastinal Lymph Node Malignancy During Endobronchial Ultrasound Staging for Lung Cancer
Where
Hamilton
Age
18 years and over
People
600
Run by
McMaster University
See details and how to joinNCT06540196
Phase 1Taking people
AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors
Where
Edmonton, Montreal, Toronto
Age
18 years and over
People
434 worldwide
Run by
Amgen
See details and how to joinNCT07094113
Phase 1Taking people
Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers
Where
Montreal, Toronto
Age
18 years to 100 years
People
162 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06562192
Phase 1Taking people
A Study of BMS-986488 as Monotherapy and Combination Therapy in Participants With Advanced Malignant Tumors
Where
Montreal, Québec, Vancouver
Age
18 years and over
People
437 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT06764771
Phase 1Taking people
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
Where
Montreal, Toronto
Age
18 years and over
People
714 worldwide
Run by
Seagen, a wholly owned subsidiary of Pfizer
See details and how to joinNCT05208762 · EU 2023-506604-18-00
Phase 1Taking people
A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors
Where
Montreal, Ottawa, Toronto
Age
18 years and over
People
914 worldwide
Run by
Seagen, a wholly owned subsidiary of Pfizer
See details and how to joinNCT06131840 · EU 2023-505858-18-00
Phase 1Taking people
A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
Where
Ottawa, Toronto
Age
18 years and over
People
710 worldwide
Run by
Incyte Corporation
See details and how to joinNCT06179160 · EU 2023-507091-47-00
Phase 1Taking people
A Study to Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors.
Where
Montreal, Toronto, Vancouver
Age
18 years and over
People
240 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT06476808 · EU 2025-523067-38-01
Phase 3Taking people
Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer
Where
Edmonton, Toronto, Winnipeg
Age
18 years and over
People
320 worldwide
Run by
Canadian Cancer Trials Group
See details and how to joinNCT06686771
Phase 2Taking people
Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer
Where
Montreal
Age
18 years to 70 years
People
170 worldwide
Run by
Iovance Biotherapeutics, Inc.
See details and how to joinNCT04614103 · EU 2024-510778-26-00
Phase 1Taking people
Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan
Where
Calgary, Montreal, Toronto
Age
18 years and over
People
694 worldwide
Run by
AbbVie
See details and how to joinNCT05005403
No phaseTaking people
Marathon of Hope Cancer Centres Network Study for Ontario (MOHCCN-O)
Where
Kingston, Ottawa, Toronto
Age
18 years and over
People
500
Run by
University Health Network, Toronto
See details and how to joinNCT05403177
No phaseTaking people
Using ctDNA to Detect Minimal Residual Disease After Lung Cancer Resection
Where
Toronto
Age
18 years and over
People
360
Run by
University Health Network, Toronto
See details and how to joinNCT05254782
No phaseTaking people
Ontario-wide Cancer TArgeted Nucleic Acid Evaluation
Where
Hamilton, Kingston, London, Ottawa, Toronto
Age
18 years and over
People
10,000
Run by
University Health Network, Toronto
See details and how to joinNCT02906943
Phase 1/2Taking people
A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies
Where
Toronto, Vancouver
Age
18 years and over
People
252 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT07223047
Phase 1/2Taking people
A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements
Where
Edmonton, Ontario, Ottawa, Toronto, Vancouver
Age
12 years and over
People
500 worldwide
Run by
Turning Point Therapeutics, Inc.
See details and how to joinNCT03093116 · EU 2024-512606-25-00
Phase 3Taking people
Phase 3 Study of Taletrectinib vs Placebo as an Adjuvant Therapy in ROS1 Positive NSCLC (TRUST-IV)
Where
Montreal, Toronto
Age
18 years and over
People
180 worldwide
Run by
Nuvation Bio Inc.
See details and how to joinNCT07154706 · EU 2025-521971-29-00
No phaseTaking people
LIVInG With chrONic Cancer TrEatments (LONGEVITI) Study
Where
Edmonton
Age
18 years to 90 years
People
75
Run by
University of Alberta
See details and how to joinNCT05645510
No phaseTaking people
Feasibility of Evaluating Gene Alteration Analysis Using Samples Obtained by EBUS-TBNA in Patients With Lung Cancer
Where
Toronto
Age
18 years and over
People
400
Run by
University Health Network, Toronto
See details and how to joinNCT01487603
No phaseTaking people
Endobronchial Ultrasound-guided Transbronchial Needle Aspiration for Lymph Node Staging in Patients With Non-small Cell Lung Cancer Pursuing Stereotactic Body Radiotherapy (SBRT)
Where
Toronto
Age
18 years and over
People
150
Run by
University Health Network, Toronto
See details and how to joinNCT01786590