Lung cancer trials in Italy

In Italy 272 Also abroad 2746

272 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 15 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Phase II Study of Radiotherapy Followed by Durvalumab and Ceralasertib in Stage III NSCLC Patients With Thoracic Relapses +/- Oligometastases After PACIFIC Regimen
Where
Brescia, Florence, Genova, Milan, Padova, Parma
Age
18 years and over
People
21 worldwide
Run by
Mario Negri Institute for Pharmacological Research
See details and how to joinNCT06680050
No phaseTaking people
Effects of Genomic Profiles on Thromboembolic Risk in Patients With Locally Advanced or Metastatic Non-small-cell Lung Cancer
Where
Perugia
Age
18 years and over
People
500
Run by
University Of Perugia
See details and how to joinNCT07288632
Phase 2Taking people
Neoadjuvant Chemo-immunotherapy for Stage III PD-L1 Positive Non-Small Cell Lung Cancer (NSCLC)
Where
Rome
Age
18 years to 99 years
People
30
Run by
Fondazione Ricerca Traslazionale
See details and how to joinNCT07264647
Phase 2Taking people
Randomized Trial Comparing Standard of Care Versus Immune- Based Combination in Relapsed Stage III Non-small-cell Lung Cancer (NSCLC) Pretreated With Chemoradiotherapy and Durvalumab
Where
Bari, Candiolo, Florence, Lecco, Meldola, Modena, Monza, Naples, Negrar, Novara, Padova, Parma, Pavia, Piacenza, Ponderano, Reggio Emilia, Rome, Treviglio, Verona, IRCCS Istituti Fisioterapici Ospitalieri- Istituto Nazionale tumori Regina Elena, Azienda USL Toscana Sud Est -Ospedale Misericordia - Grosseto
Age
18 years and over
People
176
Run by
Fondazione Ricerca Traslazionale
See details and how to joinNCT05568212 · EU 2024-520081-65-00
No phaseNot yet taking people in Italy
Neutrophil Biomarker Test for Predicting Clinical Benefit From Immunotherapy Based on Flow Cytometry Analysis
Where
Milan
Age
18 years and over
People
600 worldwide
Run by
OncoHost Ltd.
See details and how to joinNCT07246759
No phaseTaking people
First-line Therapy With Nivolumab Plus Ipilimumab in Combination With Chemotherapy for Metatastatic NSCLC (NICReWo Trial)
Where
Pavia
People
300
Run by
Fondazione IRCCS Policlinico San Matteo di Pavia
See details and how to joinNCT07190677
No phaseTaking people
The Role of DNA and RNA in NGS Analyses for Advaced Stage NSCLC Patients
Where
Bologna
Age
18 years and over
People
10
Run by
IRCCS Azienda Ospedaliero-Universitaria di Bologna
See details and how to joinNCT07188480
No phaseTaking people
The LungVision Navigational Platform for Preoperative Labeling of Pulmonary Ground Glass Nodules With Fiducial Markers
Where
Bologna
Age
18 years and over
People
5
Run by
IRCCS Azienda Ospedaliero-Universitaria di Bologna
See details and how to joinNCT07180823
No phaseNot yet taking people in Italy
Athletic Intervention After THoracic surgEry for luNg cAncer: a Pilot Study
Where
Pavia
Age
18 years and over
People
10
Run by
Fondazione IRCCS Policlinico San Matteo di Pavia
See details and how to joinNCT07159646
No phaseTaking people
Patient Reported Outcome Measurements (PROMs) Impact on Clinical Outcome in firsT Line settIng Non- Small-Cell Lung Cancer (NSCLC) According to Chemo- Immunotherapy reGimen
Where
Milan
Age
18 years and over
People
144
Run by
IRCCS San Raffaele
See details and how to joinNCT07061379
No phaseTaking people
Development of Innovative Preclinical Ex Vivo Models for the Study of Sarcomas and Metastases From Solid Tumors
Where
Bologna
Age
Up to 85 years
People
125
Run by
Istituto Ortopedico Rizzoli
See details and how to joinNCT07112989
No phaseTaking people
EMPATHY NSCLC: European Registry for Plasma-Based Molecular Profiling in Advanced NSCLC Patients
Where
Naples
Age
18 years and over
People
1,000 worldwide
Run by
Hedera Dx SA
See details and how to joinNCT07096258
Phase 2Taking people
Repurposing statins as adjuvants for cancer patients receiving therapy with immune checkpoint inhibitors: the STARK trial
Where
Bergamo, Milan, Orbassano, Padova
Age
18 years and over
People
90
Run by
Universita Degli Studi Di Padova
See details and how to join2024-518500-47-00
No phaseNot yet taking people in Italy
Study of Atezolizumab in Advanced Non-oncogene-addicted NSCLC With PD-L1 ≥50%, Including Longitudinal c-FLIP Assessment in Monocytic MDSCs.
Where
Rome
Age
18 years and over
People
107
Run by
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
See details and how to joinNCT07051928
Phase 1/2Taking people
FIH Trial of VERT-002 in Patients With Locally Advanced or Metastatic Solid Tumors With MET Alterations
Where
Orbassano
Age
18 years and over
People
140 worldwide
Run by
Pierre Fabre Medicament
See details and how to joinNCT06669117 · EU 2024-512760-64-00
No phaseTaking people
Exercise and Nutrition on Early-stage NSCLC Outcomes: the STARLighT Study
Where
Verona
Age
18 years and over
People
324
Run by
Universita di Verona
See details and how to joinNCT07042724
Phase 2Taking people
APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
Where
Ancona, Bologna, Meldola, Milan, Padova, Turin
Age
18 years and over
People
497 worldwide
Run by
Apollomics Inc.
See details and how to joinNCT03175224 · EU 2024-514542-37-00
Phase 2Taking people
Pembrolizumab and Olaparib Treatment of Extensive Small Cell Lung Cancer (ES-SCLC)
Where
Bari, Bologna, Meldola, Monza, Naples, Padova, Pesaro, Ravenna, Reggio Emilia, Rimini, Rome, Varese
Age
18 years and over
People
60
Run by
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
See details and how to joinNCT05623319 · EU 2024-514666-39-00
No phaseTaking people
Rarecells Molecular Biomarkers for Early Detection of Lung Cancer
Where
Roma
Age
35 years to 85 years
People
50
Run by
Rarecells Diagnostics SAS
See details and how to joinNCT06546007
No phaseTaking people
Long-term Follow-up of Checkpoint Inhibitors-induced Ileo-colitis
Where
Pavia
Age
18 years and over
People
250
Run by
Fondazione IRCCS Policlinico San Matteo di Pavia
See details and how to joinNCT06899789
Phase 2Taking people
Atezolizumab and Rechallenge Chemotherapy in Relapsed Patients With Extensive-stage Small Cell Lung Cancer (ES-SCLC).
Where
Aviano, Bari, Bologna, Camaiore, Carpi, Cuneo, Florence, Lucca, Mantova, Meldola, Milan, Modena, Monza, Naples, Orbassano, Padova, Parma, Perugia, Reggio Emilia, Rome, Sassari, Terni, Udine, Verona
Age
18 years and over
People
142
Run by
Gruppo Oncologico Italiano di Ricerca Clinica
See details and how to joinNCT06663098 · EU 2024-511945-20-00
No phaseNot yet taking people in Italy
Vapor Ablation for Localized Cancer Lesions
Where
Ancona
Age
18 years and over
People
10 worldwide
Run by
Uptake Medical Technology, Inc.
See details and how to joinNCT03514329
No phaseTaking people
Transcriptional Framework for the Molecular Diagnosis of Response to Immunotherapy in Lung Cancer With Agnostic Potential
Where
Rome
Age
18 years and over
People
256
Run by
Regina Elena Cancer Institute
See details and how to joinNCT06807307
No phaseTaking people
AI-HOPE Lung Cancer: Building a Predictive Tool for Metastatic Lung Cancer
Where
Milan
Age
18 years and over
People
2,000
Run by
IRCCS San Raffaele
See details and how to joinNCT06788366
No phaseTaking people
A Study to Describe the Diagnostic and Therapeutic Path of Patients with NSCLC in Early Stage and Locally Advanced
Where
Brescia, Campobasso, Catania, Florence, Genova, Messina, Milan, Naples, Novara, Padova, Palermo, Perugia, Pistoia, Pordenone, Potenza, Ravenna, Reggio Emilia, Roma, San Giovanni Rotondo, Varese, Verona
Age
18 years and over
People
600
Run by
MSD Italia S.r.l.
See details and how to joinNCT06467383