Lung cancer trials in Italy

In Italy 272 Also abroad 2746

272 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 15 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Extracellular Vesicles and Chemotherapy-Induced Peripheral Neuropathy
Where
Milan
Age
18 years and over
People
120
Run by
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
See details and how to joinNCT07558447
No phaseNot yet taking people in Italy
Bronchoscopic Microwave Ablation of Lung Tissue in Surgical Candidates - UK
Where
Milan
Age
18 years and over
People
18 worldwide
Run by
Creo Medical Limited
See details and how to joinNCT06869122
No phaseTaking people
RATS Sleeve Lobectomy After Neo-Chemo-IO for NSCLC
Where
Cosenza
People
100 worldwide
Run by
Shanghai Chest Hospital
See details and how to joinNCT07541521
Phase 2/3Taking people
A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination with Osimertinib as First-Line Treatment in Adult Participants with Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer
Where
Milan, Orbassano, Perugia, Rome
Age
18 years and over
People
50 worldwide
Run by
AbbVie Deutschland GmbH & Co. KG
See details and how to join2024-518586-10-00
No phaseTaking people
Downstaging and RATS After Neo-Chemo-IO: Impact on Surgical Outcomes in NSCLC
Where
Cosenza
People
200 worldwide
Run by
Shanghai Chest Hospital
See details and how to joinNCT07528066
Phase 1Active, not recruiting
Phase Ib Study of the Safety of T-DXd and Immunotherapy Agents With and Without Chemotherapy in Advanced or Metastatic HER2+, Non-squamous NSCLC
Where
Milan, Monza, Naples
Age
18 years and over
People
304 worldwide
Run by
AstraZeneca
See details and how to joinNCT04686305 · EU 2023-504949-31-00
Phase 2Taking people
A multicenter single-arm phase II interventional study to evaluate the activity and safety of the combination of Platinum-Pemetrexed based chemotherapy plus Lorlatinib in ALK positive Non-Small Cell Lung Cancer (NSCLC) with exclusively extracranial disease progression on Lorlatinib
Where
Aviano, Bergamo, Camaiore, Fano, Florence, Leghorn, Meldola, Milan, Monza, Padova, Parma, Perugia, Rome, Udine
Age
18 years and over
People
45
Run by
Centro Di Riferimento Oncologico Di Aviano
See details and how to join2023-506714-43-00
No phaseTaking people
Galenos 2 Immunonutrition in Head and Neck, Lung, and Rectal Cancer Patients
Where
Candiolo
Age
18 years and over
People
52
Run by
Fondazione del Piemonte per l'Oncologia
See details and how to joinNCT07514754
No phaseTaking people
GALENOS 1 in Head and Neck, Lung, and Rectal Cancer Patients
Where
Candiolo
Age
18 years and over
People
110
Run by
Fondazione del Piemonte per l'Oncologia
See details and how to joinNCT07511413
No phaseTaking people
Unveiling Malnutrition and Metabolic Changes in Lung Cancer Patients: Setting the Basis for Precision Nutrition Models.
Where
Parma
Age
18 years to 85 years
People
180 worldwide
Run by
Fundación Investigación E Innovación Biomédica Hospital Universitario Infanta Sofia-Henares
See details and how to joinNCT07486947
No phaseTaking people
Low-glucose/High-fat Intake Dietary Regimen as a Tool for Empowering Diagnostic Accuracy of 2-[18F]FDG PET/CT in Lepidic-predominant Growth Lung Adenocarcinoma
Where
Candiolo
Age
18 years and over
People
30
Run by
Fondazione del Piemonte per l'Oncologia
See details and how to joinNCT07479095
No phaseTaking people
Magnetic Resonance Imaging of the Lung: Oncological Applications
Where
Pavia
Age
18 years and over
People
50
Run by
Fondazione IRCCS Policlinico San Matteo di Pavia
See details and how to joinNCT07486219
No phaseTaking people
Progel Platinum for Air Leak Reduction After VATS Lobectomy for NSCLC
Where
Bolzano, Candiolo, Florence, Milan, Palermo, Pisa
Age
18 years to 99 years
People
160
Run by
Fondazione del Piemonte per l'Oncologia
See details and how to joinNCT07479277
No phaseTaking people
Insights on Dissemination of Lung Cancer
Where
Bologna
Age
18 years and over
People
100
Run by
IRCCS Azienda Ospedaliero-Universitaria di Bologna
See details and how to joinNCT07476495
No phaseTaking people
A Study of Biological, Genetic, and Constitutional Factors and Non-invasive Monitoring to Assess Personal Cancer Risks
Where
Candiolo
Age
18 years and over
People
850
Run by
Fondazione del Piemonte per l'Oncologia
See details and how to joinNCT07469709
No phaseTaking people
The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study
Where
Brescia, Negrar
Age
18 years and over
People
8,000 worldwide
Run by
UMC Utrecht
See details and how to joinNCT04075305
No phaseTaking people
Observational, Prospective, Multi-centric Study Exploring HER2 Mutations Incidence and Therapeutic Management in aNSCLC
Where
Aviano, Bari, Ferrara, Genova, Lido di Camaiore, Lucca, Meldola, Milan, Modena, Monza, Orbassano, Padova, Parma, Pavia, Perugia, Reggio Emilia, Roma, Rozzano, Udine, Verona
Age
18 years and over
People
50
Run by
Gruppo Oncologico Italiano di Ricerca Clinica
See details and how to joinNCT07356544
No phaseTaking people
CompArative Analysis Between, Thymic, pulmonaRy and Pancreatic Well Differentiated High Grade Neuroendocrine Tumors
Where
Milan
People
34
Run by
European Institute of Oncology
See details and how to joinNCT07429851
Phase 2Not yet taking people in Italy
A Multicenter Open-label Phase II Study of Cemiplimab Plus Chemotherapy, Selected on the Basis of Baseline Cytidine Deaminase Activity, in Advanced Squamous Non-small Cell Lung Cancer
Where
Bologna, Camaiore, Cuneo, Ferrara, Lucca, Mantova, Meldola, Parma, Pisa, Poggibonsi, Prato, Reggio Emilia, Saronno, Sassari, Terni
Age
18 years to 64 years
People
108
Run by
Gruppo Oncologico Italiano di Ricerca Clinica
See details and how to joinNCT07418931 · EU 2024-517799-40-00
No phaseTaking people
Stereotactic Body Radiotherapy (SBRT) for Reirradiation of Inoperable Lung Lesions
Where
Bergamo, Bologna, Catania, Milan, Naples, Negrar, Roma, Rozzano, Venezia, Verona
Age
18 years and over
People
150
Run by
Istituto Clinico Humanitas
See details and how to joinNCT07401615
Phase 2Taking people
Phase II Trial of Amivantamab Plus Monochemotherapy in Platinum Unfit NSCLC Patients With EGFR exon20 Insertion Mutations.
Where
Roma
Age
18 years to 99 years
People
33
Run by
Fondazione Ricerca Traslazionale
See details and how to joinNCT07392658
No phaseTaking people
Molecular Phenotyping of Primitive Lung Cancer and Metastatic Site
Where
Milan
Age
18 years and over
People
25
Run by
European Institute of Oncology
See details and how to joinNCT07325864
No phaseTaking people
Ambispective Registry of Patients Affected by Lung Cancer
Where
Pavia
Age
18 years and over
People
1,500
Run by
Fondazione IRCCS Policlinico San Matteo di Pavia
See details and how to joinNCT07274163
No phaseEnrolling by invitation
Evaluation of Lymph Node Analysis Using One Step Nucleic Acid Amplification (OSNA) in Patients With Lung Cancer Who Underwent Robotic Lung Resection, Comparison With Traditional Methods
Where
Pisa
Age
18 years and over
People
130
Run by
Azienda Ospedaliero, Universitaria Pisana
See details and how to joinNCT07301983
No phaseTaking people
Tumors and Respiratory System Diseases Due to Air Pollution: New Biomarkers of Exposure and Effects
Where
Bologna, Foggia
Age
18 years and over
People
300
Run by
IRCCS Azienda Ospedaliero-Universitaria di Bologna
See details and how to joinNCT06800586