Lupus (SLE) trials in Australia

In Australia 24 Also abroad 354

24 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
Rollover Study for Participants Who Have Completed a Previous Clinical Study With Anifrolumab (Saphnelo) and Clinically Benefited From Continued Treatment
Where
Melbourne, Mitcham, Westmead
Age
5 years to 80 years
People
1,072 worldwide
Run by
AstraZeneca
See details and how to joinNCT07691970
Phase 3Taking people
Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension).
Where
Maroochydore
Age
12 years to 100 years
People
550 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06133972 · EU 2023-505929-14-00
Phase 1Taking people
To Evaluate the Effects of Cevostamab in Participants With Systemic Lupus Erythematosus With or Without Active Lupus Nephritis
Where
Parkville
Age
18 years to 75 years
People
46 worldwide
Run by
Genentech, Inc.
See details and how to joinNCT07629583 · EU 2025-522904-26-00
Phase 1Taking people
A Trial in Healthy Adult Participants and Adults With Autoimmune Diseases to Test How HBM7020 is Tolerated and How it Behaves in the Body
Where
Brisbane
Age
18 years to 75 years
People
63
Run by
Otsuka Pharmaceutical Development & Commercialization, Inc.
See details and how to joinNCT07649265
Phase 3Taking people
A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease
Where
Maroochydore, Melbourne, New Lambton Heights
Age
18 years to 75 years
People
202 worldwide
Run by
EMD Serono Research & Development Institute, Inc.
See details and how to joinNCT07332481 · EU 2025-523871-44-00
Phase 3Taking people
A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2)
Where
Clayton
Age
18 years to 75 years
People
202 worldwide
Run by
EMD Serono Research & Development Institute, Inc.
See details and how to joinNCT07355218 · EU 2025-524855-30-00
Phase 3Taking people
A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus
Where
Box Hill, Footscray, Ipswich
Age
18 years to 75 years
People
600 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT07438496 · EU 2025-523552-31-00
Phase 1Taking people
A Clinical Study of MK-1045 in People With Lupus or Rheumatoid Arthritis (MK-1045-004)
Where
Southport
Age
18 years to 75 years
People
21 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT07363590 · EU 2025-523412-36-00
Phase 1Taking people
Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants
Where
Birtinya, Clayton
Age
18 years to 65 years
People
48 worldwide
Run by
AstraZeneca
See details and how to joinNCT07201558 · EU 2025-522273-10-00
Phase 2Taking people
A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE)
Where
Heidelberg, Murdoch
Age
18 years to 74 years
People
405 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT07409181 · EU 2025-523488-39-00
Phase 2Taking people
A Study to Investigate Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Anifrolumab in Pediatric Participants 5 to < 18 Years of Age With Systemic Lupus Erythematosus
Where
Nedlands, Parkville, Southport, Westmead
Age
5 years to 17 years
People
24 worldwide
Run by
AstraZeneca
See details and how to joinNCT07630714 · EU 2025-524578-41-00
Phase 1Taking people
A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus
Where
Parkville, Victoria Park
Age
18 years to 70 years
People
24 worldwide
Run by
Cullinan Therapeutics Inc.
See details and how to joinNCT06613360 · EU 2024-518780-36-00
Phase 1/2Taking people
A Study to Test CRT-402 in Refractory Autoimmune Disease
Where
Nedlands
Age
18 years and over
People
34
Run by
Myeloid Therapeutics
See details and how to joinNCT07778446
Phase 1Taking people
A Study to Evaluate the Safety and Activity of SAR448501/DR-0201 in Patients With Autoimmune Rheumatic Diseases
Where
Melbourne
Age
18 years to 75 years
People
62 worldwide
Run by
Sanofi
See details and how to joinNCT06647069
Phase 1Taking people
A Study of LY4298445 in Healthy Participants and Participants With Systemic Lupus Erythematosus (SLE) or Rheumatoid Arthritis (RA)
Where
Brisbane, Melbourne
Age
18 years to 55 years
People
68 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07276958 · EU 2026-527207-25-00
Phase 2Taking people
A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases
Where
Perth
Age
18 years to 75 years
People
220 worldwide
Run by
Amgen
See details and how to joinNCT06570798
Phase 1Enrolling by invitation
A Study of KITE-363 in Participants With Refractory Autoimmune Diseases
Where
Fitzroy, Syndey
Age
18 years and over
People
52 worldwide
Run by
Kite, A Gilead Company
See details and how to joinNCT07038447
Phase 1/2Taking people
A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE
Where
Darlinghurst, Melbourne
Age
18 years to 70 years
People
150 worldwide
Run by
AstraZeneca
See details and how to joinNCT06897930
Phase 1Taking people
A Study of Intravenous CPTX2309 in Healthy Participants and Participants With Moderate to Severe Rheumatoid Arthritis (RA) or Systemic Lupus Erythematosus (SLE)
Where
Bayswater, Herston, Nedlands
Age
18 years to 65 years
People
64
Run by
Capstan Therapeutics
See details and how to joinNCT06917742
Phase 1Taking people
A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases
Where
Brisbane, Camperdown, Clayton
Age
18 years and over
People
125 worldwide
Run by
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
See details and how to joinNCT07115745 · EU 2024-517681-41-00
Phase 1/2Taking people
A Phase 1/2 Study of NKX019 in Subjects With Autoimmune Disease (Ntrust-1)
Where
Parkville
Age
18 years to 75 years
People
120 worldwide
Run by
Nkarta, Inc.
See details and how to joinNCT06557265
Phase 1/2Taking people
A Phase 1/2a Study of DB-2304 in Healthy Adults and SLE/CLE Participants
Where
Melbourne
Age
18 years to 70 years
People
148 worldwide
Run by
DualityBio Inc.
See details and how to joinNCT06625671
Phase 1Taking people
A Phase 1 Study of HB2198 in Participants With Moderately to Severely Active Systemic Lupus Erythematosus (SLE)
Where
Brisbane
Age
18 years to 65 years
People
30
Run by
Hinge Bio
See details and how to joinNCT07491900
No phaseTaking people
Validation of the Lupus Low Disease Activity State (LLDAS) in the Asia Pacific Region
Where
Adelaide, Clayton, Fitzroy
Age
18 years and over
People
5,000 worldwide
Run by
Monash University
See details and how to joinNCT03138941