Lupus (SLE): open trials in United States

100 open trials have a site in United States. Registry data; only the trial team decides who can take part.

NCT07221565
Electromagnetic Immunotherapy Mapping and Cytokine Forecasting Study (QSIT)
Trial Treatment · Phase 1/2 · Truway Health, Inc.
Truway Health, Inc. www.truwayhealth.com (401 E 34th Street, S11P, New York, NY 10016), New York
Registry updated 2026-05-22
NCT07225543
2-HOBA in Systemic Lupus Erythematosus
Trial Treatment · Phase 2 · Vanderbilt University Medical Center
Vanderbilt University Medical Center, Nashville
Registry updated 2026-05-22
NCT04751396
Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors
Research · M.D. Anderson Cancer Center
M D Anderson Cancer Center, Houston
Registry updated 2026-05-20
NCT00198068
Predictors of Pregnancy Outcome in Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS)
Research · Hospital for Special Surgery, New York
This trial only enrols pregnant participants
Johns Hopkins Hospital, Baltimore · Northwestern University, Chicago · University of Chicago, Chicago · Hospital for Special Surgery, New York · NYU Langone Medical Center/Hospital for Joint Diseases, New York · Columbia University Medical Center, New York · Oklahoma Medical Research Foundation, Oklahoma City · University of Utah Salt Lake City, Salt Lake City
Registry updated 2026-04-28
NCT07219563
Alnuctamab for Refractory SLE (LATTE Study)
Trial Treatment · Phase 1 · Icahn School of Medicine at Mount Sinai
Icahn School of Medicine at Mount Sinai, New York
Registry updated 2026-04-21
NCT05934149
Lupus Landmark Study: A Prospective Registry and Biorepository
Research · Lupus Research Alliance
Emory University, Atlanta · Wallace Rheumatic Studies Center, Beverly Hills · University of Alabama at Birmingham, Birmingham · Brigham and Women's Hospital, Boston · UNC- Chapel Hill, Chapel Hill · University of Chicago, Chicago · The MetroHealth System, Cleveland · UT Southwestern Medical Center, Dallas · UCLA, Los Angeles · The Feinstein Institutes for Medical Research, Manhasset · University of Miami, Miami · Vanderbilt University Medical Center, Nashville · Columbia University Medical Center, New York · Northwell Health, New York · Washington University, St Louis · SUNY Upstate, Syracuse · University of Arizona, Tucson · Georgetown University, Washington D.C. · University of Massachusetts Memorial Health, Worcester
Registry updated 2026-04-15
NCT07011043
A Phase 1b Study of Budoprutug in Systemic Lupus Erythematosus (SLE)
Trial Treatment · Phase 1 · Climb Bio, Inc.
Allen · San Antonio
Registry updated 2026-03-27
NCT06375993
A Phase 1 Study of Prulacabtagene Leucel (Prula-cel, Formerly ADI-001) in Autoimmune Disease
Trial Treatment · Phase 1 · Adicet Therapeutics
Roswell Park Comprehensive Cancer Center, Buffalo · Adicet Clinical Trials, Redwood City
Registry updated 2026-03-19
NCT04402086
Rheumatology Patient Registry and Biorepository
Research · Yale University
Yale New Haven Hospital, New Haven
Registry updated 2026-02-13
NCT07403188
A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101
Research · Phase 2/3 · Kyverna Therapeutics
University of Colorado Denver, Denver
Registry updated 2026-02-11
NCT06804057
CorEvitas Systemic Lupus Erythematosus (SLE) Drug Safety and Effectiveness Registry
Research · CorEvitas
CorEvitas, Waltham
Registry updated 2026-02-06
NCT06927219
Research Accelerated by You Lupus Registry
Research · Lupus Foundation of America
Washington D.C.
Registry updated 2026-01-23
NCT00512694
Duke Lupus Registry
Research · Duke University
Duke University Medical Center, Durham
Registry updated 2026-01-08
NCT03276923
Maternal Autoimmune Disease Research Alliance (MADRA) Registry
Research · Duke University
Duke University, Durham
Registry updated 2026-01-08
NCT07282392
Helping Lupus Patients Manage Fibromyalgia Symptoms Through Emotional Awareness and Expression Therapy (EAET)
Trial Treatment · University of Utah
University of Utah, Salt Lake City
Registry updated 2025-12-29
NCT06465147
REACT-01: Reversing Autoimmunity Through Cell Therapy
Trial Treatment · Phase 1 · Seattle Children's Hospital
Seattle Children's Hospital, Seattle
Registry updated 2025-12-12
NCT07107659
Safety and Efficacy of ONT01 in Lupus
Trial Treatment · Early phase 1 · Hospital for Special Surgery, New York
Hospital for Special Surgery, New York
Registry updated 2025-11-20
NCT07225387
Safety and Efficacy of Combination Belimumab and Voclosporin in the Treatment of Proliferative Forms of Lupus Glomerulopathy: Synergy Trial
Trial Treatment · Phase 4 · NephroNet, Inc.
Piedmont Physicians Rheumatology, Atlanta · Nephrology Clinical Trials Unit The Ohio State University Wexner Medical Center, Columbus · AARA Clinical Research, Fort Worth · AARA Clinical Research, Glendale · Georgia Nephrology Research Institute, Lawrenceville · Parris & Associates, Lawrenceville · Oklahoma Medical Research Foundation, Oklahoma City
Registry updated 2025-11-06
NCT06232304
Transforming Care for Individuals With Childhood-onset Systemic Lupus Erythematosus
Trial Treatment · Michigan State University
University of Alabama Birmingham Hospital, Birmingham · Cincinnati Children's Hospital Medical Center, Cincinnati · Helen DeVos Children's Hospital, Grand Rapids · Children's Hospital of New Orleans/ Tulane University, New Orleans · Seattle Children's Hospital, Seattle · Montefiore Medical Center, The Bronx
Registry updated 2025-10-30
NCT05029336
Autologous Stem Cell Transplant (ASCT) for Autoimmune Diseases
Trial Treatment · Phase 2 · Stephan Grupp MD PhD
Children's Hospital of Philadelphia, Philadelphia
Registry updated 2025-10-14
NCT06737380
UC-MSC Cell Therapy Study for Systemic Lupus Erythematosus (SLE) Patients
Trial Treatment · Phase 1 · LiveKidney.Bio
Medical University of South Carolina, Charleston
Registry updated 2025-09-11
NCT06340750
BAFF CAR-T Cells (LMY-920) for Systemic Lupus Erythematosus
Trial Treatment · Phase 1 · Luminary Therapeutics
Nationwide Children's, Columbus
Registry updated 2025-06-03
NCT01802034
Repository of Novel Analytes Leading to Autoimmune, Inflammatory and Diabetic Nephropathies (RENAL AID)
Research · The Rogosin Institute
The Rogosin Institute, New York
Registry updated 2025-04-04
NCT06581562
Open-label Single-Center Study to Evaluate the Safety and Efficacy of Combining Rituximab and AB-101 in B-cell Associated Autoimmune Diseases.
Trial Treatment · Phase 1 · IRIS Research and Development, LLC
IRIS Research and Development LLC, Plantation
Registry updated 2024-09-03
NCT05508009
Early Trial of Allogeneic Hematopoietic Stem Cell Transplantation for Patients Who Will Receive a Kidney Transplant From the Same Donor
Trial Treatment · Phase 1/2 · Alice Bertaina
Lucile Packard Children's Hospital, Palo Alto
Registry updated 2023-07-17

All Lupus (SLE) trials and the map

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