Macular degeneration trials in United States

In United States 95 Also abroad 220

95 trials · From ClinicalTrials.gov, checked 14 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Development and Evaluation of Functional Visual Field and Navigation Endpoints in Moderate to Profound Inherited Retinal Disease (DEFINE-IRD)
Where
Irvine
Age
18 years and over
People
25
Run by
Ray Therapeutics, Inc.
See details and how to joinNCT07502664
No phaseTaking people
Progression of Early Atrophic Lesions
Where
Salt Lake City
Age
50 years and over
People
125
Run by
University of Utah
See details and how to joinNCT05959005
No phaseTaking people
Real-World Evaluation of AI Enabled Multi-Spectral Imaging (MSI) for AMD Biomarker Detection
Where
Woodbridge
Age
40 years and over
People
1,000
Run by
AI-Spectral
See details and how to joinNCT07446582
No phaseTaking people
Active AMD Study to Improve Function in Veterans
Where
Decatur
Age
65 years to 89 years
People
70
Run by
VA Office of Research and Development
See details and how to joinNCT05932069
No phaseTaking people
Factors in Learning And Plasticity: Macular Degeneration
Where
Birmingham
Age
18 years to 89 years
People
60
Run by
University of Alabama at Birmingham
See details and how to joinNCT05454124
Phase 1Taking people
A Phase 1 Study of ABF-101 in Single- and Multiple-Ascending Doses
Where
Dallas
Age
18 years to 50 years
People
68
Run by
Aptabio Therapeutics, Inc.
See details and how to joinNCT07330674
Early phase 1Taking people
Feasibility and Safety of MB-102 in Ocular Angiography as Compared to Fluorescein Sodium
Where
Ann Arbor
Age
18 years and over
People
10
Run by
MediBeacon
See details and how to joinNCT04008121
Phase 2Taking people
Dark Adaptation as an Early Indicator of Response to Statin Therapy for Intermediate AMD
Where
Boston
Age
50 years to 85 years
People
21
Run by
Massachusetts Eye and Ear Infirmary
See details and how to joinNCT04735263
Phase 1/2Taking people
A Phase 1/2 Study to Evaluate the Safety and Efficacy of Intravitreal Administration of BS01 in Patients With Geographic Atrophy Secondary to Dry AMD
Where
Edison
Age
50 years to 85 years
People
40
Run by
Bionic Sight LLC
See details and how to joinNCT07158775
Phase 1/2Taking people
A Phase 1/2, First-in-Human Dose Escalation/Expansion Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of a Subretinal Injection of SB-007 in Subjects With Stargardt Disease (STGD1)
Where
Aurora, Boston, Dallas, Miami, Portland
Age
12 years to 65 years
People
57
Run by
Splice Bio
See details and how to joinNCT06942572
Phase 3Not yet taking people in United States
A Phase 3 Clinical Trial to Compare RBS-001 to Eylea® in Subjects With Neovascular Age-Related Macular Degeneration
Where
Abilene, Erie, Germantown, Phoenix, Springdale, Willow Park
Age
50 years and over
People
434
Run by
Rophibio, Inc.
See details and how to joinNCT06470373
No phaseTaking people
A Prospective Observational Study to Assess the Reliability and Validity of the MLSDT
Where
Dallas
Age
18 years and over
People
30
Run by
Nanoscope Therapeutics Inc.
See details and how to joinNCT06805474
No phaseTaking people
NYSCF Scientific Discovery Biobank
Where
New York
Age
30 days and over
People
10,000
Run by
New York Stem Cell Foundation Research Institute
See details and how to joinNCT06203106
Phase 1Taking people
Study to Evaluate the Safety of CG-P5 Peptide Eye Drops in Patients Diagnosed With Age-related Wet Macular Degeneration
Where
Augusta, Carmel, Deerfield Beach, Erie, Fargo, Manchester, Philadelphia
Age
50 years and over
People
45
Run by
Caregen Co. Ltd.
See details and how to joinNCT06132035
No phaseTaking people
Observational Study to Assess Endpoint Operational Feasibility & Measurement Properties in Patients with Retinal Degeneration
Where
Irvine
Age
18 years and over
People
120
Run by
Ray Therapeutics, Inc.
See details and how to joinNCT06375239
No phaseTaking people
Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMD
Where
Asheville, Birmingham, Cleveland, Eatontown, Houston, Lawrence, Loma Linda, Long Beach, Omaha, Sarasota
Age
65 years and over
People
125
Run by
VisionCare, Inc.
See details and how to joinNCT05438732
No phaseTaking people
Novel Glaucoma Diagnostics
Where
Philadelphia
Age
18 years and over
People
5,000
Run by
Wills Eye
See details and how to joinNCT00286637
Phase 2Enrolling by invitation
Long-term Follow-Up Study of RGX-314 and Fellow Eye Substudy
Where
Baltimore, Boston, Germantown, Philadelphia, Phoenix, Reno, Santa Barbara, The Woodlands
Age
50 years and over
People
865 worldwide
Run by
AbbVie
See details and how to joinNCT03999801 · EU 2023-505750-17-00
No phaseTaking people
OCT Angiography in Wet AMD
Where
Portland
Age
50 years to 100 years
People
160
Run by
Oregon Health and Science University
See details and how to joinNCT02253030
No phaseEnrolling by invitation
Post-Approval Study of the Implantable Miniature Telescope
Where
Ann Arbor, Atlanta, Beverly Hills, Chandler, Chesterfield, Eugene, Fullerton, Loma Linda, McAllen, New York, Parker, Pensacola, Phoenix, Sacramento, Sarasota
Age
65 years and over
People
770
Run by
VisionCare, Inc.
See details and how to joinNCT01757132