Melanoma trials in Netherlands

In Netherlands 43 Also abroad 579

40 of 43 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 15 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Completed
A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)
Where
Utrecht
Age
6 months to 17 years
People
370 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT02332668 · EU 2022-501257-36-00
Phase 3Taking people
Immunotherapy or Targeted Therapy With or Without Stereotactic Radiosurgery for Patients With Brain Metastases From Melanoma or Non-small Cell Lung Cancer
Where
Amsterdam
Age
18 years and over
People
180 worldwide
Run by
ETOP IBCSG Partners Foundation
See details and how to joinNCT05522660
Phase 4Taking people
Dabrafenib and/or Trametinib Rollover Study
Where
Utrecht
Age
18 years to 100 years
People
100 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT03340506 · EU 2023-509318-13-00
Phase 1Not yet taking people in Netherlands
Phase 1 Study of PF-08046033 in Advanced Solid Tumors
Where
Amsterdam
Age
18 years and over
People
250 worldwide
Run by
Pfizer
See details and how to joinNCT07519655
Phase 3Taking people
SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma
Where
Amsterdam, Groningen, Rotterdam
Age
18 years and over
People
450 worldwide
Run by
Immatics US, Inc.
See details and how to joinNCT06743126 · EU 2024-517062-42-00
Phase 1Taking people
A Study of BI 3810944 in Patients With Advanced Cancer
Where
Nijmegen
Age
18 years and over
People
69 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT07224425 · EU 2025-522045-21-00
Phase 2Taking people
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Where
Amsterdam, Groningen, Leiden, Maastricht, Nijmegen
Age
18 years and over
People
740 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06172478 · EU 2023-507641-29-00
Phase 1/2Taking people
A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)
Where
Amsterdam, Groningen, Nijmegen, Rotterdam, Utrecht
Age
18 years and over
People
680 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06330064 · EU 2023-509632-26-00
Phase 2Not yet taking people in Netherlands
PHOENIX - ECP: Extracorporeal PHotopheresis for immune-related cOlitis and/or hEpatitis in advanced melaNoma with inadequate response to steroId eXposure
Where
Amsterdam
Age
18 years and over
People
46 worldwide
Run by
Therakos Europe Limited
See details and how to join2026-526261-14-00
Phase 3Taking people
Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.
Where
Amsterdam
Age
18 years to 70 years
People
670 worldwide
Run by
Iovance Biotherapeutics, Inc.
See details and how to joinNCT05727904 · EU 2022-503140-41-00
Phase 1/2Completed
A Clinical Imaging Study of the Changes in [18F]F-AraG Uptake Following Anti-PD-1 Therapy in Non-small Cell Lung Cancer
Where
Amsterdam
Age
18 years and over
People
15
Run by
Amsterdam UMC, location VUmc
See details and how to joinNCT05701176 · EU 2024-517960-45-00
Phase 2/3Completed
Assessment of PET Tracers to Evaluate T Cell Change and Activation in Relation to Immunotherapy Treatment Response in Non-Small Cell Lung Cancer
Where
Amsterdam
Age
18 years and over
People
34
Run by
Amsterdam UMC, location VUmc
See details and how to joinNCT06457789 · EU 2023-509486-20-00
No phaseTaking people
Timing of Immunotherapy in Melanoma
Where
Amsterdam, Leiden, Nijmegen, Rotterdam
Age
18 years and over
People
170
Run by
Radboud University Medical Center
See details and how to joinNCT07696715
Phase 2Taking people
Dietary Fiber to Induce Gut Microbiota-mediated Response to Immunotherapy in Melanoma.
Where
Groningen, Nijmegen
Age
18 years and over
People
70
Run by
Radboud University Medical Center
See details and how to joinNCT07686835
No phaseTaking people
Novel Ga68-PSMA PET/CT-tracer to Differentiate Between Radiation Necrosis and Tumor Progression in Brain Metastases
Where
Amsterdam
People
100
Run by
The Netherlands Cancer Institute
See details and how to joinNCT07511933
Phase 2Not yet taking people in Netherlands
Phase II randomized study evaluating a Pragmatic approach to Adoptive Cell Therapy (ACT) using an IL2 analog (ANV419/ANV600) vs High dose IL2 after Tumor Infiltrating Lymphocytes (TIL) Therapy in patients with melanoma, NSCLC and cervical cancer. The PragmaTIL
Where
Amsterdam
Age
18 years and over
People
24 worldwide
Run by
Vall D Hebron Institute Of Oncology
See details and how to join2023-506400-99-00
Phase 3Taking people
Adjuvant Tebentafusp in High Risk Ocular Melanoma
Where
Leiden, Rotterdam
Age
18 years and over
People
290 worldwide
Run by
European Organisation for Research and Treatment of Cancer - EORTC
See details and how to joinNCT06246149 · EU 2023-510333-28-00
Phase 1/2Not yet taking people in Netherlands
Comparing Intravenous or Intradermal Administration of Anti-CTLA-4 in Combination With Anti-PD1 Treatment in Patients With Melanoma
Where
Amsterdam
Age
18 years and over
People
18
Run by
Amsterdam UMC, location VUmc
See details and how to joinNCT07615881 · EU 2024-516545-39-01
Phase 3Not yet taking people in Netherlands
Neoadjuvant Darovasertib in Primary Uveal Melanoma
Where
Rotterdam
Age
18 years and over
People
520 worldwide
Run by
IDEAYA Biosciences
See details and how to joinNCT07015190 · EU 2025-522387-32-00
Phase 3Taking people
NO Re-excision MelanomA - NORMA 2
Where
Alkmaar, Almere Stad, Amsterdam, Apeldoorn, Arnhem, Eindhoven, Enschede, Gouda, Groningen, Hilversum, Hoorn, Leiden, Maastricht, Rotterdam, 's-Hertogenbosch, The Hague, Utrecht, Zwolle
People
1,749
Run by
Marieke Goodijk
See details and how to joinNCT07530887
Phase 1/2Taking people
Research on two creams (Monobenzon / Imiquimod) together with the standard treatment for advanced or metastatic melanoma (ImMI).
Where
Amsterdam
Age
18 years and over
People
18
Run by
Amsterdam UMC Stichting
See details and how to join2024-520052-19-04
Phase 2/3Taking people
Contrast-enhanced Ultrasound for Sentinel Node Detection
Where
Amsterdam
Age
18 years and over
People
91
Run by
The Netherlands Cancer Institute
See details and how to joinNCT07310758
No phaseTaking people
Explorative Study on Addition of High-fiber Dried Chicory Root in Patients With an Intermediate to High-risk Cutaneous Melanoma.
Where
Groningen
Age
18 years and over
People
20
Run by
University Medical Center Groningen
See details and how to joinNCT07206017
Phase 1/2Taking people
ACTME
Where
Leiden
Age
18 years and over
People
58
Run by
Leids Universitair Medisch Centrum (LUMC)
See details and how to join2024-516125-31-02
No phaseTaking people
Omitting Therapeutic Lymph Node Dissection in Patients With Melanoma (Stage 3) and Major Pathological Response in the Index Lymph Node
Where
Rotterdam
Age
16 years and over
People
213
Run by
D.J. (Dirk) Grünhagen
See details and how to joinNCT06754904