Myelodysplastic syndromes: open trials in Canada

20 open trials have a site in Canada. Registry data; only the trial team decides who can take part.

NCT05554406
Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)
Trial Treatment · Phase 2 · National Cancer Institute (NCI)
Arthur J.E. Child Comprehensive Cancer Centre, Calgary · University of Alberta Hospital, Edmonton · CSSS Champlain-Charles Le Moyne, Greenfield Park · QEII Health Sciences Centre/Nova Scotia Health Authority, Halifax · CIUSSSEMTL-Hopital Maisonneuve-Rosemont, Montreal · Jewish General Hospital, Montreal · Ottawa Hospital and Cancer Center-General Campus, Ottawa · University Health Network, Princess Margaret Hospital, Toronto · CancerCare Manitoba, Winnipeg
Registry updated 2026-11-06
NCT06499285
A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions
Trial Treatment · Phase 3 · Takeda
University of Alberta Hospital, Edmonton · Nova Scotia Health Authority, Centre for Clinical Research, Halifax · London Health Sciences Centre, London · Sunnybrook Research Institute, Odette Cancer Center, Toronto · Princess Margaret Cancer Centre, Toronto · Providence Hematology - Vancouver, Vancouver
Registry updated 2026-11-06
NCT05564390
MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)
Trial Treatment · Phase 2 · National Cancer Institute (NCI)
Arthur J.E. Child Comprehensive Cancer Centre, Calgary · University of Alberta Hospital, Edmonton · CSSS Champlain-Charles Le Moyne, Greenfield Park · QEII Health Sciences Centre/Nova Scotia Health Authority, Halifax · Juravinski Cancer Centre at Hamilton Health Sciences, Hamilton · CIUSSSEMTL-Hopital Maisonneuve-Rosemont, Montreal · Jewish General Hospital, Montreal · Ottawa Hospital and Cancer Center-General Campus, Ottawa · Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto · University Health Network, Princess Margaret Hospital, Toronto · CancerCare Manitoba, Winnipeg
Registry updated 2026-11-02
NCT00900198
Collection of Tissue Samples for Cancer Research
Research · National Cancer Institute (NCI)
Princess Margaret Hospital Cancer Centre, Toronto
Registry updated 2026-10-27
NCT07155226
Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression
Trial Treatment · Phase 1/2 · AstraZeneca
Montreal · Toronto
Registry updated 2026-10-23
NCT06782373
A Study to Assess the Effectiveness and Safety of Pacritinib in Patients With VEXAS Syndrome (PAXIS)
Trial Treatment · Phase 2 · Swedish Orphan Biovitrum
Queen Elizabeth II Health Sciences Center, Halifax · Hospital du Sacre-Coeur in Montreal, Montreal · Princess Margaret Cancer Centre, Toronto · Vancouver Coastal Health Research Institute, Vancouver
Registry updated 2026-10-16
NCT06641414
Lisaftoclax (APG-2575) Combined With Azacytidine (AZA) in the Treatment of Patients With Higher-risk Myelodysplastic Syndrome (GLORA-4).
Trial Treatment · Phase 3 · Ascentage Pharma Group Inc.
Calgary · Montreal · Toronto · Vancouver
Registry updated 2026-10-13
NCT04256317
A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)
Trial Treatment · Phase 2/3 · Taiho Oncology, Inc.
Eastern Health - Health Sciences Centre, St. John's · Princess Margaret Cancer Centre, Toronto
Registry updated 2026-10-06
NCT04996875
(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis
Trial Treatment · Phase 2 · Cogent Biosciences, Inc.
University of Alberta Hospital, Edmonton · St. Michael's Hospital, Unity Health Toronto, Toronto
Registry updated 2026-09-15
NCT04726241
The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study
Trial Treatment · Phase 1/2 · PedAL BCU, LLC
Alberta Children's Hospital, Calgary · University of Alberta Hospital, Edmonton · IWK Health Centre, Halifax · Children's Hospital, London · The Montreal Children's Hospital of the MUHC, Montreal · Centre Hospitalier Universitaire Sainte-Justine, Montreal · Children'S Hospital Of Eastern Ontario, Ottawa · CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL), Québec · Centre Hospitalier Universitaire de Sherbrooke-Fleurimont, Sherbrooke · Hospital for Sick Children, Toronto · British Columbia Children's Hospital, Vancouver · CancerCare Manitoba, Winnipeg
Registry updated 2026-08-25
NCT04093570
A Study for Participants Who Participated in Prior Clinical Studies of ASTX727 (Standard Dose)
Trial Treatment · Phase 2 · Taiho Oncology, Inc.
University of Alberta Hospital, Edmonton · QEII Health Sciences Centre, Nova Scotia · The Ottawa Hosptial, Ottawa · Princess Margaret Cancer Center, Toronto · Sunnybrook Health Sciences Centre, Toronto
Registry updated 2026-07-28
NCT04064060
A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials
Trial Treatment · Phase 3 · Celgene
Toronto · Toronto · Toronto
Registry updated 2026-07-01
NCT07528417
Evaluation of Antibiotic Prophylaxis in Myelodysplastic Syndromes and Acute Myeloid Leukemia (MYELO-CAN:ABX)
Trial Treatment · Phase 2 · University of Manitoba
CancerCare Manitoba, Winnipeg
Registry updated 2026-06-29
NCT06847867
A Study of Momelotinib in Participants With Low-risk Myelodysplastic Syndrome
Trial Treatment · Phase 2 · GlaxoSmithKline
Calgary · Toronto
Registry updated 2026-06-02
NCT06599762
Evaluation of Tranexamic Acid in Myelodysplastic Syndromes and Acute Myeloid Leukemia
Trial Treatment · Phase 2 · University of Manitoba
CancerCare Manitoba, Winnipeg
Registry updated 2026-04-22
NCT04988555
A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)
Trial Treatment · Phase 1/2 · Sumitomo Pharma America, Inc.
Tom Baker Cancer Center, Calgary · University of Alberta, Edmonton
Registry updated 2026-03-24
NCT06510868
Evaluating Myelodysplastic Syndrome Risks in NET Patients Planned for Peptide Radionuclide Therapy
Research · University Health Network, Toronto
Princess Margaret Cancer Centre, Toronto
Registry updated 2026-03-05
NCT07301866
A Study Testing an Improved Dose of UM171 to Help Make Cord Blood Transplants More Effective and Safe.
Trial Treatment · Phase 1/2 · Ciusss de L'Est de l'Île de Montréal
Hôpital Maisonneuve-Rosemont, Montreal
Registry updated 2025-12-24
NCT06270771
OURA Ring Wearable Testing in MDS Patients: a Feasibility and Discovery Pilot Study
Research · Sunnybrook Health Sciences Centre
Sunnybrook Health Sciences Research Centre, Toronto
Registry updated 2025-07-08
NCT02760238
Myeloproliferative Neoplasms (MPNs) Patient Registry
Research · University Health Network, Toronto
Princess Margaret Cancer Centre, Toronto
Registry updated 2024-08-27

All Myelodysplastic syndromes trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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