Myeloproliferative neoplasms: open trials in Spain

28 open trials have a site in Spain. Registry data; only the trial team decides who can take part.

NCT04877522
Asciminib Roll-over Study
Trial Treatment · Phase 4 · Novartis Pharmaceuticals
Institut Catala d'Oncologia, Badalona · Hospital Clinic de Barcelona, Barcelona · Hospital Universitari Vall d'Hebron, Barcelona · Hospital Universitario Basurto, Bilbao · Institut Catala D'oncologia, L'Hospitalet de Llobregat · Hospital Universitario 12 de Octubre, Madrid · Hospital Universitario de la Princesa, Madrid · Hospital Universitario Ramón y Cajal, Madrid · Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife · Complexo Hospitalario Universitario De Santiago, Santiago de Compostela · Hospital Universitario Virgen De La Macarena, Sevilla · Hospital Universitario Y Politecnico La Fe, Valencia
Registry updated 2026-11-09
NCT07357727
A Phase 3 Study of Pelabresib (DAK539) and Ruxolitinib in Myelofibrosis (MF)
Trial Treatment · Phase 3 · Novartis Pharmaceuticals
Hospital General Universitario Dr. Balmis, Alicante · Hospital Universitari Vall d'Hebron, Barcelona · Hospital Clinic de Barcelona, Barcelona · Hospital Universitario Donostia, Donostia · Institut Català d'Oncologia, Girona · El Hospital Universitario De Gran Canaria Dr. Negrin, Las Palmas De Gran Canaria · Area De Salud De Leon Y El Bierzo, Leon · Institut Catala D'oncologia, L'Hospitalet de Llobregat · Hospital General Universitario Gregorio Marañón, Madrid · Hospital Universitario Ramón y Cajal, Madrid · Hospital Universitario Regional de Málaga, Málaga · University Clinical Hospital Virgen De La Arrixaca, Murcia · Hospital Universitario de Navarra, Pamplona · Hospital Universitario Quironsalud Madrid, Pozuelo de Alarcón · Hospital Universitario De Salamanca, Salamanca
Registry updated 2026-11-06
NCT07623161
A Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking Ruxolitinib
Trial Treatment · Phase 3 · Takeda
Institut Catala d'Oncologia, Badalona · Hospital Universitari Vall d'Hebron, Barcelona · El Hospital Universitario De Gran Canaria Dr. Negrin, Las Palmas De Gran Canaria · Institut Catala D'oncologia, L'Hospitalet de Llobregat · Hospital Universitario Ramón y Cajal, Madrid · Hospital Universitario Virgen de la Victoria, Málaga · Complejo Asistencial Universitario de Salamanca, Salamanca · Hospital Universitario Y Politecnico La Fe, Valencia
Registry updated 2026-11-06
NCT07623200
A Phase 3 Study of INCA033989 Versus Best Available Therapy in Participants With Essential Thrombocythemia
Trial Treatment · Phase 3 · Incyte Corporation
Hospital General Unviersitario de Alicante, Alicante · Hospital Clinic de Barcelona (Hospital Clinic i Provincial), Barcelona · Hospital Universitario Vall d'Hebron, Barcelona · Hospital Universitario de Basurto, Bilbao · Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas de Gran Canaria · Instituto Catalan de Oncologia Hospital Duran i Reynals, L'Hospitalet de Llobregat · Hospital Universitario 12 de Octubre, Madrid · Hospital Universitario Ramón y Cajal, Madrid · Puerta de Hierro Majadahonda University Hospital, Majadahonda · Hospital Universitario Virgen de la Victoria, Málaga · Hospital Universitari Son Espases, Palma · Hospital Clinico Universitario de Salamanca, Salamanca · Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela · Hospital Universitario Doctor Peset, Valencia · Hospital Universitario Miguel Servet (Hospital Infantil), Zaragoza
Registry updated 2026-11-05
NCT06150157
A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms
Trial Treatment · Phase 1 · Janssen Research & Development, LLC
Hosp. Univ. Germans Trias I Pujol, Badalona · Hosp. Clinico Univ. de Valencia, Valencia
Registry updated 2026-11-04
NCT06517875
Study of Momelotinib in Combination With Luspatercept in Participants With Transfusion Dependent Myelofibrosis
Trial Treatment · Phase 2 · GlaxoSmithKline
Institut Catala d'Oncologia, Badalona · Hospital Universitari Vall d'Hebron, Barcelona · El Hospital Universitario De Gran Canaria Dr. Negrin, Las Palmas De Gran Canaria · Hospital Universitario Ramón y Cajal, Madrid · Hospital General Universitario Gregorio Marañón, Madrid · Hospital Universitario Virgen de la Victoria, Málaga · Hospital Universitario Y Politecnico La Fe, Valencia
Registry updated 2026-11-04
NCT07441694
Study of INCA036978 in Participants With Myeloproliferative Neoplasms
Trial Treatment · Phase 1 · Incyte Corporation
Hospital Universitari Germans Trias i Pujol, Badalona · Hospital Universitario de Gran Canaria Dr Negrín, Las Palmas de Gran Canaria · Hospital Universitario 12 de Octubre, Madrid
Registry updated 2026-10-30
NCT07429266
INTREPID: A Study of Sapablursen Evaluating the Safety and Efficacy in Participants With Polycythemia Vera (PV)
Trial Treatment · Phase 3 · Ono Pharmaceutical Co., Ltd.
Institut Catala d'Oncologia, Badalona · Hospital Universitario de Cruces, Barakaldo · Hospital del Mar, Barcelona · Hospital Clinic de Barcelona, Barcelona · Hospital Universitari Vall d'Hebron, Barcelona · Hospital de la Santa Creu i Sant Pau, Barcelona · Institut Catala D'oncologia, L'Hospitalet de Llobregat · Hospital General Universitario Gregorio Marañón, Madrid · Hospital Universitario Ramón y Cajal, Madrid · Hospital Universitario 12 de Octubre, Madrid · Hospital Universitario Virgen de la Victoria, Málaga · Hospital General Universitario Morales Meseguer, Murcia · Hospital Universitario de Navarra, Pamplona · Complejo Asistencial Universitario de Salamanca, Salamanca · Complexo Hospitalario Universitario De Santiago, Santiago de Compostela · Fundacio Assistencial De Mutua De Terrassa Fpc, Terrassa · Hospital Clinico Universitario de Valencia, Valencia
Registry updated 2026-10-29
NCT07469891
A Phase 1 Study of PRT12396 in Participants With Select Myeloproliferative Neoplasms
Trial Treatment · Phase 1 · Prelude Therapeutics Incorporated
Hospital Clinic de Barcelona, Barcelona · Hospital Universitario Ramón y Cajal, Madrid · Hospital Universitario 12 de Octubre, Madrid · Hospital Universitario Virgen de la Victoria, Málaga · Hospital Clinico Universitario de Valencia, Valencia
Registry updated 2026-10-29
NCT06343805
A Phase 1 Study of LY5830966 in Participants With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i)
Trial Treatment · Phase 1 · Ajax Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company
Hospital Clinic de Barcelona, Barcelona · Hospital Universitario Ramón y Cajal, Madrid · Hospital General Universitario Gregorio Marañón, Madrid
Registry updated 2026-10-09
NCT04176198
A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis
Trial Treatment · Phase 1/2 · Sumitomo Pharma America, Inc.
Institut Catala d'Oncologia, Badalona · Hospital Universitario De Salamanca, Salamanca · Hospital Universitario Y Politecnico La Fe, Valencia
Registry updated 2026-10-02
NCT07394153
Pacritinib For Bone Marrow Fibrosis In Patients With Myelofibrosis Who Have Thrombocytopenia
Trial Treatment · Phase 2 · Grupo Español de Enfermedades Mieloproliferativas Crónicas PH Negativas
Hospital del Mar, Barcelona · Hospital Clinic de Barcelona, Barcelona · Hospital Universitari Vall d'Hebron, Barcelona · Hospital de Jerez de la Frontera, Jerez de la Frontera · El Hospital Universitario De Gran Canaria Dr. Negrin, Las Palmas De Gran Canaria · Hospital Universitario 12 de Octubre, Madrid · Hospital Universitario Fundación Jiménez Díaz, Madrid · Hospital General Universitario Gregorio Marañón, Madrid · Hospital Universitario Ramón y Cajal, Madrid · Hospital General Universitario Morales Meseguer, Murcia · Hospital Universitario De Salamanca, Salamanca · Hospital Clinico Universitario de Valencia, Valencia · Consorcio Hospital General Universitario de Valencia, Valencia
Registry updated 2026-10-02
2024-511309-47-00
A Phase 2 study to evaluate the efficacy and safety of selinexor monotherapy in subjects with JAK inhibitor-naïve myelofibrosis and moderate thrombocytopenia.
Trial Treatment · Phase 2 · Karyopharm Therapeutics Inc.
Institut Catala d'Oncologia, Badalona · Hospital San Pedro De Alcántara, Cáceres · Institut Català d'Oncologia, Girona · El Hospital Universitario De Gran Canaria Dr. Negrin, Las Palmas De Gran Canaria · University Clinical Hospital Virgen De La Arrixaca, Murcia · Hospital Universitario Central De Asturias, Oviedo · Hospital Universitario De Salamanca, Salamanca · Hospital Clinico Universitario de Valencia, Valencia
Registry updated 2026-09-25
NCT06987058
RVU120 Rollover Study
Trial Treatment · Phase 2 · Ryvu Therapeutics SA
Clínica Universidad de navarra, Pamplona
Registry updated 2026-09-17
NCT04996875
(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis
Trial Treatment · Phase 2 · Cogent Biosciences, Inc.
Hospital Universitario Vall d'Hebron, Barcelona · Institut Catala d Oncologia Hospital Duran i Reynals, Barcelona · Hospital Universitario Ramón y Cajal, Madrid
Registry updated 2026-09-15
2023-504724-25-00
Adding Navtemadlin to Ruxolitinib for Patients with Myelofibrosis
Trial Treatment · Phase 3 · Kartos Therapeutics Inc.
Institut Catala d'Oncologia, Badalona · Hospital Universitari Vall d'Hebron, Barcelona · Hospital del Mar, Barcelona · El Hospital Universitario De Gran Canaria Dr. Negrin, Las Palmas De Gran Canaria · Institut Catala D'oncologia, L'Hospitalet de Llobregat · Hospital Universitario 12 de Octubre, Madrid · Hospital Universitario Ramón y Cajal, Madrid · Hospital Universitario Virgen de la Victoria, Málaga · University Hospital Son Espases, Palma · Hospital Universitario De Salamanca, Salamanca · Hospital Universitario Y Politecnico La Fe, Valencia · Hospital Clinico Universitario de Valencia, Valencia · Hospital QuirónSalud Zaragoza, Zaragoza
Registry updated 2026-09-14
NCT04771130
A Study of BGB-11417 in Participants With Myeloid Malignancies
Trial Treatment · Phase 1/2 · BeOne Medicines
Hospital de la Santa Creu i Sant Pau, Barcelona · Hospital Universitario De Salamanca, Salamanca · University Hospital Virgen Del Rocio S.L., Sevilla · Hospital Universitario Y Politecnico La Fe, Valencia
Registry updated 2026-09-14
2024-515252-20-00
A Phase I/II with Ruxolitinib in Patients with Myelofibrosis (MF) who are Unresponsive to JAK inhibitors (HEMA-MED)
Trial Treatment · Phase 1/2 · iOnctura SA
Hospital Universitari Vall d'Hebron, Barcelona · Institut Catala D'oncologia, L'Hospitalet de Llobregat · Hospital Universitario HM Sanchinarro, Madrid · Hospital Universitario De Salamanca, Salamanca
Registry updated 2026-09-11
NCT06533813
Clinical Epidemiology in Contemporary Patients With Myelofibrosis.
Research · FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS
Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) - Hospital Clinic, Barcelona · Hematology and Hemotherapy Department, 12 de Octubre University Hospital, Madrid
Registry updated 2026-07-09
NCT07203768
A ELN-Multicenter Study on Phenotypic Evolution and Clinical Outcomes
Research · FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS
IDIBAPS, Hospital clinic, Barcelona · 12 Octubre University Hospital, Madrid
Registry updated 2026-07-09
NCT04064060
A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials
Trial Treatment · Phase 3 · Celgene
Barakaldo · Barcelona · Barcelona · Madrid · Oviedo · Salamanca · Seville · Valencia
Registry updated 2026-07-01
NCT06887803
A Study of Roginolisib in Combination With Ruxolitinib in Patients With Myelofibrosis (MF) Who Are Unresponsive to JAK Inhibitors
Trial Treatment · Phase 1/2 · iOnctura
Vall d'Hebron University Hospital, Barcelona · Avigunda Gran via de l'Hospitalet 199-203, 08908 L'Hospitalet de Llobregat, Barcelona · START Madrid - CIOCC, Madrid · Hospital Universitario De Salamanca, Salamanca
Registry updated 2026-06-23
2025-523864-19-00
Phase 2 Study of iadademstat for the treatment of patients with essential thrombocythemia resistant/intolerant to hydroxyurea.
Trial Treatment · Phase 2 · Oryzon Genomics S.A.
Hospital del Mar, Barcelona · Institut Catala d Oncologia - L Hospitalet de Llobregat, Barcelona · Hospital Universitari Vall d'Hebron, Barcelona · Hospital Clinic de Barcelona, Barcelona · Hospital de Jerez de la Frontera, Jerez de la Frontera · El Hospital Universitario De Gran Canaria Dr. Negrin, Las Palmas De Gran Canaria · University Clinical Hospital Virgen De La Arrixaca, Murcia · Hospital General Universitario Morales Meseguer, Murcia · Complexo Hospitalario Universitario De Santiago, Santiago de Compostela
Registry updated 2026-04-13
NCT06093672
Study on Efficacy and Safety of Givinostat Versus Hydroxyurea in Patients With Polycythemia Vera
Trial Treatment · Phase 3 · Italfarmaco
Hospital General Universitario Dr. Balmis, Alicante · Hospital Germans Trias i Pujol, Badalona · Hospital Universitario Ramón y Cajal, Madrid · Hospital Universitario Virgen de la Victoria, Málaga · Hospital Universitario Y Politecnico La Fe, Valencia
Registry updated 2026-03-25
NCT05980806
A Study of Selinexor Monotherapy in Subjects With JAK Inhibitor-naïve Myelofibrosis and Moderate Thrombocytopenia
Trial Treatment · Phase 2 · Karyopharm Therapeutics Inc
Hospital Germans Trias i Pujol, Badalona · Hospital San Pedro De Alcántara, Cáceres · Hospital Clínico Universitario Virgen de la Arrixaca, El Palmar · Institut Català D'Oncologia Girona, Girona · Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas de Gran Canaria · Hospital Universitario Central De Asturias, Oviedo · Complejo Asistencial Universitario de Salamanca - Hospital Clínico, Salamanca · Hospital Clinico Universitario de Valencia, Valencia
Registry updated 2026-02-12

All Myeloproliferative neoplasms trials and the map

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