Chronic rhinosinusitis with nasal polyps trials in United States

In United States 14 Also abroad 58

14 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

Phase 4Taking people
Biologics in Chronic Rhinosinusitis With Nasal Polyposis
Where
Charleston, Gainesville, Nashville, Phoenix, Portland
Age
18 years and over
People
504
Run by
Medical University of South Carolina
See details and how to joinNCT06824649
Phase 3Taking people
A Study to Assess the Efficacy and Safety of GSK5784283 (Felcorekibart) in Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Where
Los Angeles, Louisville, Spartanburg, Tulsa
Age
18 years and over
People
218 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT07782970
Phase 3Taking people
A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)
Where
Arcadia, Birmingham, Boise, Boston, Charleston, Chicago, Cincinnati, Colorado Springs, Columbia, Columbus, Dallas, Hamilton, Houston, Huntsville, Irvine, La Mesa, Long Beach, Mandeville, McKinney, Miami, Milwaukee, New York, Norfolk, Orlando, Overland Park, Pompano Beach, Richmond, Roseville, San Antonio, St Louis, Tampa, The Bronx, Torrance, Tucson, White Marsh
Age
12 years and over
People
510 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT06338995 · EU 2023-508760-29-00
No phaseTaking people
Paclitaxel-Coated Balloon Treatment of Chronic Rhinosinusitis
Where
Birmingham, Cedar Rapids, Charleston, Charlottesville, Colorado Springs, Dallas, Fort Worth, Huntsville, Kansas City, Louisville, McKinney, Philadelphia, San Diego, The Bronx
Age
18 years and over
People
300
Run by
Airiver Medical, Inc.
See details and how to joinNCT07290140
Phase 3Taking people
A Study to Assess the Efficacy and Safety of GSK5784283 (Felcorekibart) Compared With Placebo in Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Where
Greenville, Plano, Sherman Oaks
Age
18 years and over
People
218 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT07782957
Phase 3Taking people
Efficacy and Safety of 186 mcg of OPN-375 Nasal Spray Twice a Day (BID) in Adolescents With Chronic Rhinosinusitis Without Nasal Polyps
Where
Atlanta, Aurora, Austin, Colorado Springs, Columbia, Gilbert, Huntsville, Los Angeles, Louisville, Norfolk, North Charleston, Oklahoma City, Orange, Orangeburg, Rochester, Sacramento, Salt Lake City, San Antonio, San Diego, Springfield, Torrance, Towson, Tulsa
Age
12 years to 17 years
People
84
Run by
Optinose US Inc.
See details and how to joinNCT06850805
No phaseTaking people
CRS Questionnaire Validation Project
Where
Boston, Chicago, Philadelphia, Santa Monica, Virginia City
Age
18 years and over
People
1,000 worldwide
Run by
The European Forum for Research and Education in Allergy and Airway Diseases
See details and how to joinNCT06970977
No phaseNot yet taking people in United States
Active vs. Passive VR During Office-based ENT Procedures
Where
Los Angeles
Age
18 years and over
People
132
Run by
Cedars-Sinai Medical Center
See details and how to joinNCT07599826
No phaseTaking people
Olfactory Cleft Obstruction and Electrophysiological Field Potentials Predict Olfactory Restoration by Dupilumab in CRSwNP Patients.
Where
Chicago
Age
18 years to 65 years
People
30
Run by
Northwestern University
See details and how to joinNCT06892704
No phaseTaking people
Cognitive and Immunologic Profiles of Patients With Olfactory Dysfunction After Smell Training
Where
Cleveland
Age
18 years and over
People
52
Run by
The Cleveland Clinic
See details and how to joinNCT07681973
Phase 1Taking people
A Study of BBT002 in Healthy Volunteers (HVs) and in Adult Patients With Chronic Obstructive Pulmonary Disease (COPD) or Chronic Rhiosininusitis With Nasal Polyps (CRSwNP)
Where
Bowling Green, New York, Owensboro
Age
18 years to 80 years
People
286 worldwide
Run by
Bambusa Therapeutics
See details and how to joinNCT06944925 · EU 2025-523142-28-00
No phaseEnrolling by invitation
Evaluation of the Safety and Performance of a Bioresorbable Nasal Dressing Containing Mometasone Furoate (MF)
Where
Atlanta, Charleston, Chicago, Colorado Springs, Houston, Ogden, Puyallup, Shreveport, Towson
Age
18 years and over
People
110
Run by
Polyganics BV
See details and how to joinNCT07286201
No phaseTaking people
3D Printing to Improve Nasal Irrigation Outcome
Where
Columbus
Age
18 years to 75 years
People
200
Run by
Ohio State University
See details and how to joinNCT06118554
Phase 4Taking people
Interleukin-4Ra Blockade by Dupilumab Decreases Staphylococcus Colonization and Increases Microbial Diversity in CRSwNP
Where
Charlottesville
Age
18 years to 65 years
People
20
Run by
University of Virginia
See details and how to joinNCT05094570