Obesity trials in South Africa

In South Africa 9 Also abroad 1939

9 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 3Not yet taking people in South Africa
A Research Study to Investigate How Well the Medicine CagriSema Lowers High Blood Pressure in People Living With High Blood Pressure and Obesity
Where
Durban, eMkhomazi, Gauteng, Johannesburg, Midrand
Age
18 years and over
People
1,408 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07919405
Phase 3Taking people
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
Where
Bellville, Bloemfontein, Cape Town, Chatsworth, Claremont, Durban, eMkhomazi, Johannesburg, Midrand, Wentworth
Age
18 years and over
People
4,500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07667803
Phase 3Not yet taking people in South Africa
A Research Study to Look at How Well Zenagamtide Works Compared to Placebo in People With Established Atherosclerotic Cardiovascular Disease and Either Overweight or Obesity
Where
Bloemfontein, Cape Town, Centurion, Durban, East London, eMkhomazi, Gauteng, Johannesburg, Krugersdorp, KwaDukuza, Mossel Bay, Paarl, Cape Town, Port Elizabeth, Pretoria, Roodepoort, Somerset West, Worcester
Age
45 years to 64 years
People
8,500 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07861100 · EU 2026-525182-53-00
Phase 3Taking people
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
Where
Bloemfontein, Cape Town, Durban, Johannesburg, Lenasia, Mossel Bay, Paarl, Cape Town, Port Elizabeth, Pretoria, Somerset West
Age
18 years and over
People
2,500 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07564414 · EU 2025-522488-14-00
No phaseEnrolling by invitation
Cities for Better Health Childhood Obesity Prevention Initiative
Where
Johannesburg
Age
6 years to 13 years
People
36,000 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT06855563
No phaseEnrolling by invitation
Quality of Recovery and Patient Satisfaction After Metabolic Surgery at a Tertiary Hospital in Gauteng (QoRPS-MS)
Where
Ga-Rankuwa
Age
18 years and over
People
84
Run by
Sefako Makgatho Health Sciences University
See details and how to joinNCT07804290
Phase 3Taking people
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
Where
Benoni, Bloemfontein, Cape Town, Durban, East London, Johannesburg, Kempton Park, KwaDukuza, Midrand, Mossel Bay, Pietermaritzburg, Polokwane, Pretoria, Somerset West
Age
18 years and over
People
5,610 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07567001 · EU 2025-523717-29-00
No phaseTaking people
National Blood Pressure Screening in Children to Improve Paediatric Healthcare in South Africa
Where
Bloemfontein, Cape Town, Durban, Johannesburg, Mthatha, Polokwane, Port Elizabeth, Potchefstroom
Age
5 years to 18 years
People
22,464 worldwide
Run by
North-West University, South Africa
See details and how to joinNCT05982847
No phaseTaking people
Iron Absorption and Losses in Young South African Women Living Without and With Overweight and Obesity
Where
Potchefstroom
Age
18 years to 35 years
People
70
Run by
Linda Malan
See details and how to joinNCT07081152