Obesity: open trials in South Africa

9 open trials have a site in South Africa. Registry data; only the trial team decides who can take part.

NCT07919405
A Research Study to Investigate How Well the Medicine CagriSema Lowers High Blood Pressure in People Living With High Blood Pressure and Obesity
Trial Treatment · Phase 3 · Novo Nordisk A/S
Dr Vawda's site, Durban · Dr T Padayachee, eMkhomazi · Dr Moosa's Rooms, Gauteng · Soweto Clinical Trial Centre, Johannesburg · Johannesburg · Dr A Jacovides and Partners Inc, Midrand
Registry updated 2026-11-05
NCT07667803
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
Trial Treatment · Phase 3 · AstraZeneca
Bellville · Bloemfontein · Cape Town · Chatsworth · Claremont · Durban · eMkhomazi · Johannesburg · Midrand · Wentworth
Registry updated 2026-10-13
NCT07861100
A Research Study to Look at How Well Zenagamtide Works Compared to Placebo in People With Established Atherosclerotic Cardiovascular Disease and Either Overweight or Obesity
Trial Treatment · Phase 3 · Novo Nordisk A/S
IATROS International, Bloemfontein · Medi-Clinic Bloemfontein, Bloemfontein · Tread Research (Pty)Ltd, Cape Town · Prof Rayner_Division of Nephrology, Cape Town · Dr Iftikhar Osman Ebrahim, Centurion · Dr Pillay's Rooms, Durban · Clinical Projects Research (Pty) Ltd, East London · Dr T Padayachee, eMkhomazi · Dr Moosa's Rooms, Gauteng · Wits Clinical Research, Johannesburg · Ubuntu Clinical Research, Johannesburg · Soweto Clinical Trial Centre, Johannesburg · Johannesburg · DJW Research, Krugersdorp · Clinical Research Institute of South Africa, KwaDukuza · Dr Hendrik Snyman's Practice, Mossel Bay · Paarl Research Centre, Paarl, Cape Town · Phoenix Pharma, Port Elizabeth · Clinical Trials Network Pretoria, Pretoria · Clinical Trial Systems (CTC), Pretoria · Roodepoort Medicross Clinical Research Centre, Roodepoort · Clinical Trials Network Helderberg (Pty) Ltd, Somerset West · Clinical Projects Research, Worcester
Registry updated 2026-10-06
NCT07564414
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
Trial Treatment · Phase 3 · Novo Nordisk A/S
IATROS International, Bloemfontein · Medi-Clinic Bloemfontein, Bloemfontein · Tread Research (Pty)Ltd, Cape Town · Dr Pillay's Rooms, Durban · Soweto Clinical Trial Centre, Johannesburg · Johannesburg · Hemant Makan, Johannesburg · Sandton Medical Research, Johannesburg · Newtown Clinical Research, Johannesburg · Lenasia Clinical Trial Centre, Lenasia · Dr Hendrik Snyman's Practice, Mossel Bay · Paarl Research Centre, Paarl, Cape Town · Phoenix Pharma, Port Elizabeth · Clinical Trial Systems (CTC), Pretoria · Clinical Trials Network Helderberg (Pty) Ltd, Somerset West
Registry updated 2026-09-30
NCT06855563
Cities for Better Health Childhood Obesity Prevention Initiative
Trial Treatment · Novo Nordisk A/S
Johannesburg
Registry updated 2026-09-16
NCT07804290
Quality of Recovery and Patient Satisfaction After Metabolic Surgery at a Tertiary Hospital in Gauteng (QoRPS-MS)
Research · Sefako Makgatho Health Sciences University
Dr George Mukhari Hospital, Ga-Rankuwa
Registry updated 2026-09-04
NCT07567001
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
Trial Treatment · Phase 3 · Novo Nordisk A/S
East Rand Physicians Clinical Research Division (Pty) Ltd, Benoni · IATROS International, Bloemfontein · InnoMed Clinical Trial Centre, Cape Town · Tread Research (Pty)Ltd, Cape Town · Helderberg Research Institute, Cape Town · Tiervlei Trial Centre, Cape Town · Cardiac Clinical Research Unit, University of Cape Town, Cape Town · Bella Vita Clinical Research, Cape Town · Dr Pillay's Rooms, Durban · Synapta Clinical Research, Durban · Synergy Biomed Research Institute, East London · Tickerdoc Research (Pty) LTD, Johannesburg · Wits Clinical Research, Johannesburg · Johannesburg · Clinresco Centres (Pty) Ltd, Kempton Park · Clinical Research Institute of South Africa, KwaDukuza · Dr A Jacovides and Partners Inc, Midrand · Dr Hendrik Snyman's Practice, Mossel Bay · Meditrial Clinical Research Centre, Pietermaritzburg · Dr MT Makhomisane Inc, Polokwane · Clinical Trial Systems (CTC), Pretoria · Dr IO Ebrahim Inc, Pretoria · Jongaie Research, Pretoria · Clinical Trials Network Helderberg (Pty) Ltd, Somerset West
Registry updated 2026-08-18
NCT05982847
National Blood Pressure Screening in Children to Improve Paediatric Healthcare in South Africa
Research · North-West University, South Africa
University of the Free State, Bloemfontein · Red Cross War Memorial Children Hospital, Cape Town · South African Medical Research Council, Cape Town · University of Cape Town, Cape Town · University of KwaZulu-Natal, Durban · University of the Witwatersrand, Johannesburg · Walter Sisulu University, Mthatha · University of Limpopo, Polokwane · Nelson Mandela Metropolitan University, Port Elizabeth · Hypertension in Africa Research Team (HART), North-West University, Potchefstroom
Registry updated 2026-04-07
NCT07081152
Iron Absorption and Losses in Young South African Women Living Without and With Overweight and Obesity
Trial Treatment · Linda Malan
Esté Vorster Research Facility, Potchefstroom
Registry updated 2026-03-23

All Obesity trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

Report an error