Osteoporosis: open trials in United States

• NCT07920484

  A Clinical Study to Collect Real-wordt Data on Safety and Clinical Performance of the VCFix Spinal System for Treatment of Vertebral Compression Fractures of (Suspected) Osteoporotic Origin.

  Research · Amber Implants B.V.

  Montefiore Medical Center, New York · University of Oklahoma Health Campus, Oklahoma City · Rothman Orthopaedics, Philadelphia

  Registry updated 2026-11-05

• NCT05845021

  Surgeon-Initiated Bone Health Referral Pathway in Patients Undergoing Lower Extremity Arthroplasty

  Trial Treatment · Johns Hopkins University

  Charter Professional Center, Columbia

  Registry updated 2026-10-27

• NCT00024804

  A Natural History Study of Bone and Mineral Disorders

  Research · National Institute of Dental and Craniofacial Research (NIDCR)

  National Institutes of Health Clinical Center, Bethesda

  Registry updated 2026-10-26

• NCT07876882

  REMS vs DXA for Osteoporosis Diagnosis and Fracture Risk Prediction

  Research · BoneVue Diagnostics

  Rheumatology Associates of Delmarva, Easton · Rheumatology Associates of Delmarva, Salisbury

  Registry updated 2026-10-15

• NCT06558188

  Combined Anabolic Therapy

  Trial Treatment · Phase 4 · Massachusetts General Hospital

  Massachusetts General Hospital, Boston

  Registry updated 2026-10-08

• NCT07143669

  Screening Study for KIT D816V Mutated Mast Cell Disease in Select Populations

  Research · Blueprint Medicines Corporation

  Emory University, Atlanta · O'Neal Comprehensive Cancer Center at the UAB, Birmingham · AllerVie Clinical Research, Birmingham · The University of North Carolina at Chapel Hill, Chapel Hill · Medical University of South Carolina, Charleston · AIR Care, Dallas · Northwestern Medicine Allergy and Immunology, Evanston · AllerVie Health, Glenn Dale · University of Kansas Medical Center, Kansas City · Orso Health, La Jolla · Somnos Clinical Research, Lincoln · Tulane University School of Medicine, New Orleans · Mount Sinai Hospital, New York · Midwest Allergy Sinus Asthma, Normal · Allergy, Asthma & Clinical Research Center, Oklahoma City · University of Nebraska, Omaha · Allergy & Clinical Immunology Associates, Pittsburgh · Mayo Clinic - Rochester, Rochester · Kaiser Permanente - San Diego, San Diego · Orso Health, Scottsdale · Barnes-Jewish West County Hospital, St Louis · Allergy, Asthma, & Immunology Associates of Tampa Bay, Tampa · Arizona Respiratory Center, Tucson · Allergy & Asthma Clinical Research of the Bay Area, Walnut Creek · Care Access Research, Warwick

  Registry updated 2026-10-07

• NCT06118905

  Preserving Geriatric Muscle With an Osteoporosis Medication

  Trial Treatment · Phase 4 · Chrissy Kistler

  St. Barnabas Woodlands, Pittsburgh

  Registry updated 2026-09-23

• NCT06041789

  Effect of Acetylcholinesterase Inhibitors on Bone Metabolism

  Trial Treatment · Phase 2 · Duke University

  Duke Memory Disorders Clinic, Durham

  Registry updated 2026-09-21

• NCT07154719

  GLP-1R Actions on Muscle and the Skeleton

  Trial Treatment · Phase 4 · Pennington Biomedical Research Center

  Pennington Biomedical Research Center, Baton Rouge · MaineHealth Center for Clinical and Translational Science, Scarborough

  Registry updated 2026-08-27

• NCT07776613

  A Study of Romosozumab in People With Breast Cancer and Osteoporosis

  Trial Treatment · Phase 2 · Memorial Sloan Kettering Cancer Center

  Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities), Basking Ridge · Memorial Sloan Kettering Cancer Center @ Suffolk-Commack (Limited Protocol Activities), Commack · Memorial Sloan Kettering Westchester (Limited Protocol Activities), Harrison · Memorial Sloan Kettering Monmouth (Limited Protocol Activities), Middletown · Memorial Sloan Kettering Bergen (Limited Protocol Activities), Montvale · Memorial Sloan-Kettering Cancer Center, New York · Memorial Sloan Kettering Nassau (Limited Protocol Activities), Uniondale

  Registry updated 2026-08-20

• NCT07763509

  Calcium-Rich Food Versus Calcium Carbonate for Bone Health

  Trial Treatment · Cornell University

  Clinical and Translational Science Center, Weill Cornell Medical College, New York

  Registry updated 2026-08-13

• NCT07365514

  Blackcurrants Modify Gut Microbiota and Reduce Osteoporosis Risk in Postmenopausal Females

  Trial Treatment · Phase 1 · University of Connecticut

  University of Connecticut, Department of Nutritional Sciences, Storrs

  Registry updated 2026-07-23

• NCT07587775

  The Effect of Osteoporotic Medications on Vertebral Bone Quality Score

  Trial Treatment · Phase 2 · State University of New York at Buffalo

  University at Buffalo Neurosurgery, Buffalo

  Registry updated 2026-07-23

• NCT07325578

  U.S. Prospective Evaluation of EPIONE Device for Percutaneous MSK Procedures

  Trial Treatment · Precision IO Group

  Rush University Medical Center, Chicago · Baptist Hospital Of Miami, Inc, Miami · UC San Diego, San Diego

  Registry updated 2026-07-20

• NCT05764733

  Bone, Exercise, Alendronate, and Caloric Restriction

  Trial Treatment · Phase 4 · Wake Forest University Health Sciences

  University of Colorado Anschutz Medical Campus, Aurora · Atrium Health Wake Forest Baptist Medical Center, Winston-Salem

  Registry updated 2026-06-09

• NCT06811363

  Contribution of Bone to Urine Citrate

  Research · University of Texas Southwestern Medical Center

  UT Southwestern Medical Center, Dallas

  Registry updated 2026-06-03

• NCT05266976

  Mode of Exercise and Bone Biomarkers in Older Veterans

  Trial Treatment · VA Office of Research and Development

  Rocky Mountain Regional VA Medical Center, Aurora, CO, Aurora

  Registry updated 2026-05-22

• NCT07027306

  The Osteoporotic Fracture Classification-based Scoring System for Treatment Decision in Thoracolumbar Osteoporotic Fractures

  Research · AO Foundation, AO Spine

  Thomas Jefferson University Hospital, Philadelphia · University of California San Francisco (USCF) Department of Orthopaedic Surgery, San Francisco

  Registry updated 2026-05-13

• NCT07083557

  Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)

  Research · Bettina Mittendorfer

  University of Missouri - Columbia, Columbia

  Registry updated 2026-05-07

• NCT03921060

  Markers of Osteoporosis in Cystic Fibrosis

  Trial Treatment · Phase 4 · University of Texas Southwestern Medical Center

  UT Southwestern Medical Center, Dallas

  Registry updated 2026-05-05

• NCT06455085

  RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE

  Trial Treatment · University of Alabama at Birmingham

  Emory University, Atlanta · University of Alabama at Birmingham, Birmingham · The University of North Carolina at Chapel Hill, Chapel Hill · University of Illinois Chicago (UIC), UI Health, Chicago · Rush University Medical Center, Chicago · Missouri Orthopaedic Institute, Columbia · The Ohio State University, Columbus · Allina Health Orthopedics/NorthStar Trauma Network, Coon Rapids · Duke University, Durham · University of Florida - Gainesville, Gainesville · UT Health Houston, Houston · University of Iowa, Iowa City · University of Florida - Jacksonville, Jacksonville · Dartmouth-Hitchcock Clinic, Lebanon · Loyola University Chicago, Maywood · Vanderbilt University Medical Center, Nashville · Hospital for Special Surgery, New York · UAMS Health, North Little Rock · University of Nebraska Medical Center, Omaha · Mayo Clinic - Arizona, Scottsdale · Washington University in St. Louis, St Louis · Montefiore Medical Center, The Bronx · Wake Forest University Health Sciences, Winston-Salem

  Registry updated 2026-05-05

• NCT06264609

  Precision Medicine Approach for Osteoporosis - Follow Up Study

  Trial Treatment · Phase 4 · Paul F Netzel

  University of Kentucky, Lexington

  Registry updated 2026-04-01

• NCT06389539

  Synbiotic to Attenuate Resorption of the Skeleton

  Trial Treatment · Hebrew SeniorLife

  Hebrew SeniorLife, Roslindale

  Registry updated 2026-03-17

• NCT07120997

  Prunes Preventing Bone Loss in Perimenopause

  Trial Treatment · Penn State University

  Women's Health and Exercise Laboratory, The Pennsylvania State University, University Park

  Registry updated 2026-02-04

• NCT06731608

  OsteoPorotic fracTure preventION System (OPTIONS) Research Study

  Trial Treatment · Brigham and Women's Hospital

  University of Maryland, Baltimore, Department of Epidemiology and Public Health, Division of Gerontology, Baltimore · Brigham and Women's Hospital, Boston

  Registry updated 2026-01-29

All Osteoporosis trials and the map

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