Ovarian cancer trials in United States

In United States 349 Also abroad 794

349 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer
Where
Bethesda
Age
18 years to 72 years
People
332
Run by
National Cancer Institute (NCI)
See details and how to joinNCT01174121
No phaseTaking people
DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study
Where
Bethesda, Rockville
Age
1 month to 99 years
People
1,500
Run by
National Cancer Institute (NCI)
See details and how to joinNCT01247597
Phase 1Taking people
A Study of Azenosertib (ZN-c3) in Patients With Ovarian Cancer
Where
Aurora, Boston, Durham, Houston, Nashville, New York, Providence, St Louis
Age
18 years and over
People
172 worldwide
Run by
K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc
See details and how to joinNCT04516447 · EU 2025-524868-38-00
Phase 1Taking people
Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies
Where
Bethesda
Age
18 years to 120 years
People
60
Run by
National Cancer Institute (NCI)
See details and how to joinNCT04847063
Phase 3Taking people
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
Where
Aberdeen, ‘Aiea, Aitkin, Albany, Albuquerque, Allentown, Alma, Alpena, Alton, Ames, Anaconda, Anchorage, Ann Arbor, Antioch, Arroyo Grande, Ashland, Athens, Atlanta, Auburn, Augusta, Aurora, Baker City, Ballwin, Baltimore, Bardstown, Barrington, Basking Ridge, Baton Rouge, Battle Creek, Baxter, Beachwood, Bellevue, Bellflower, Bellingham, Bemidji, Bend, Berkeley, Berkeley Heights, Bethesda, Bethlehem, Beverly Hills, Billings, Birmingham, Bismarck, Bloomington, Boise, Bolivar, Boone, Bozeman, Brainerd, Branson, Bridgeport, Brighton, Brooklyn, Buffalo, Burbank, Burlingame, Burlington, Burnsville, Butte, Caldwell, Cambridge, Camden, Cameron Park, Canton, Cape Girardeau, Carbondale, Carmel, Carmichael, Carterville, Carthage, Castro Valley, Cedar Rapids, Centralia, Chadds Ford, Chambersburg, Chapel Hill, Chardon, Charlottesville, Chaska, Chelsea, Cheyenne, Chicago, Cincinnati, Clackamas, Clarkston, Cleveland, Cody, Coeur d'Alene, Colorado Springs, Columbia, Columbus, Commack, Coon Rapids, Coos Bay, Corbin, Council Bluffs, Crosslake, Crown Point, Crystal Lake, Cudahy, Dallas, Danbury, Danville, Davis, Decatur, Deer River, Delaware, Denver, Detroit, Detroit Lakes, Dixon, Downers Grove, Dublin, Duluth, Durango, Durham, Dyer, East China Township, Easton, East Stroudsburg, Edina, Edmonds, Effingham, Elgin, Elk Grove, Elkton, Elmhurst, Ely, Emeryville, Ephrata, Escanaba, Eureka, Everett, ‘Ewa Beach, Fairbanks, Fairfield, Fargo, Farmington, Fayetteville, Flint, Florham Park, Fort Collins, Fort Dodge, Fort Lauderdale, Fort Smith, Fort Wayne, Fort Worth, Fosston, Franklin, Fremont, Fresno, Fruitland, Gaffney, Gainesville, Galesburg, Garden City, Germantown, Gettysburg, Gladwin, Glens Falls, Golden, Goshen, Grafton, Grand Island, Grand Junction, Grand Rapids, Great Bend, Great Falls, Greeley, Green Bay, Greenwich, Greer, Grosse Pointe Woods, Hamilton, Hanover, Harbor City, Harrison, Hartford, Havre, Hayward, Hazel Crest, Hazleton, Helena, Hershey, Hibbing, Highlands Ranch, Hinsdale, Hobart, Honolulu, Hood River, Houston, Indianapolis, International Falls, Iowa City, Irvine, Issaquah, Jamestown, Jefferson, Jersey City, Joplin, Kalamazoo, Kalispell, Kearney, Kennewick, Kenosha, Kewanee, Lacey, La Crosse, Lafayette, La Jolla, Lake Mary, Lakewood, Lansing, Las Vegas, Lebanon, Lewes, Lexington, Libertyville, Lihue, Little Rock, Livingston, Livonia, London, Longmont, Longview, Los Angeles, Louisville, Loveland, Macomb, Mansfield, Maple Grove, Maplewood, Marinette, Marion, Marrero, Marshall, Marshalltown, Martinsburg, Mattoon, Mayfield Heights, Mentor, Merced, Meridian, Metairie, Middletown, Midland, Millville, Milwaukee, Mineola, Minneapolis, Missoula, Mitchell, Modesto, Monticello, Montvale, Moose Lake, Morgantown, Mountain View, Mount Pleasant, Mount Sterling, Mount Vernon, Mukwonago, Munster, Muskegon, Nampa, Napa, Naperville, Nashville, Nassau Bay, Newark, Newberg, New Brunswick, New Haven, New Lenox, New Orleans, New Richmond, New Ulm, New York, Niles, Normal, Norton Shores, Norwalk, Novato, Oakland, Oak Lawn, Ocoee, Oconomowoc, Oconto Falls, O'Fallon, Oklahoma City, Omaha, Ontario, Orange, Oregon City, Orlando, Orland Park, Osage Beach, Oshkosh, Ottawa, Paducah, Palo Alto, Palos Heights, Panorama City, Parkersburg, Park Rapids, Park Ridge, Parma, Pasadena, Pekin, Pensacola, Peoria, Pequot Lakes, Peru, Philadelphia, Phoenix, Pickerington, Pierre, Pine River, Pittsburg, Plainfield, Pontiac, Portland, Post Falls, Princeton, Providence, Pueblo, Quakertown, Racine, Raleigh, Rancho Cordova, Redmond, Redwood City, Reed City, Rehoboth Beach, Richardson, Richmond, Rio Rancho, Riverside, Robbinsdale, Rochester, Rockford, Rocklin, Rogers, Rohnert Park, Rolla, Roseville, Sacramento, Saginaw, Sainte Genevieve, Saint Joseph, Saint Louis Park, Saint Paul, Salt Lake City, San Diego, Sandpoint, Sandstone, San Francisco, San Jose, San Leandro, San Luis Obispo, San Marcos, San Mateo, San Rafael, Santa Barbara, Santa Clara, Santa Cruz, Santa Maria, Santa Rosa, Scarborough, Seattle, Sedro-Woolley, Sewell, Shakopee, Shawnee Mission, Sheboygan, Silverdale, Sioux Falls, Somerville, South Bend, South Jordan, South San Francisco, Spartanburg, Spokane, Spooner, Springdale, Springfield, Stamford, Staples, Stillwater, St Louis, Stockton, Stroudsburg, Sturgeon Bay, Sullivan, Summit, Sunnyvale, Superior, Sylvania, Syracuse, Tawas City, The Woodlands, Toledo, Torrance, Traverse City, Trumbull, Tualatin, Twin Falls, Two Rivers, Union, Uniondale, Urbana, Vacaville, Vallejo, Valparaiso, Vancouver, Virginia, Waconia, Walla Walla, Walnut Creek, Warren, Washington, Waterbury, Waterford, Waukesha, Wauwatosa, Webster, West Allis, West Chester, Westerly, Westerville, Westlake, Westminster, Wheat Ridge, Wheeling, Willmar, Willow Grove, Wilmington, Woodbury, Woodland, Woodland Hills, Wyoming, Yankton, York, Yorkville, Ypsilanti
Age
18 years and over
People
880 worldwide
Run by
NRG Oncology
See details and how to joinNCT06580314
Phase 2Taking people
Sacituzumab Govitecan With Bevacizumab Compared to Usual Chemotherapy (Carboplatin, Pegylated Liposomal Doxorubicin and Bevacizumab) for Treating Recurrent Platinum-Sensitive Ovarian Cancer After PARP Inhibitor Maintenance Therapy
Where
Anaconda, Billings, Cedar Rapids, Coeur d'Alene, Danville, Effingham, Fayetteville, Great Falls, Kalispell, Long Branch, Mattoon, Missoula, New Brunswick, Normal, Oklahoma City, Post Falls, Rogers, Sandpoint, Springdale, Springfield, Urbana
Age
18 years and over
People
87
Run by
National Cancer Institute (NCI)
See details and how to joinNCT07504588
Phase 3Taking people
A Study of Azenosertib (ZN-c3) Versus Investigator's Choice Chemotherapy in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Primary Peritoneal, or Fallopian Tube Cancers Positive for Cyclin E1 Protein Expression
Where
Antioch, Baltimore, Beverly Hills, Camden, Columbus, Fort Worth, Fountain Valley, Orlando, Philadelphia, Phoenix, Portland, San Francisco, Sioux Falls, Torrance, Willow Grove
Age
18 years and over
People
420 worldwide
Run by
K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc
See details and how to joinNCT07546500
Phase 1Taking people
Phase 1 Study of VT-101 in Advanced Ovarian Cancer
Where
Iowa City
Age
18 years to 99 years
People
22
Run by
Michael J. Goodheart
See details and how to joinNCT07905677
No phaseEnrolling by invitation
Developing a Gynecologic Cancer Health Promotion Community Engagement Program
Where
Philadelphia
Age
18 years and over
People
100
Run by
Abramson Cancer Center at Penn Medicine
See details and how to joinNCT07910162
No phaseEnrolling by invitation
Peer Ambassador in Gyn Onc Trials
Where
Philadelphia
Age
18 years and over
People
125
Run by
Abramson Cancer Center at Penn Medicine
See details and how to joinNCT07915336
No phaseTaking people
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
Where
Aberdeen, Abington, ‘Aiea, Akron, Albany, Albuquerque, Allentown, Alliance, Alma, Alpena, Anchorage, Ann Arbor, Antioch, Asheville, Athens, Atlanta, Augusta, Aurora, Aventura, Baker City, Baltimore, Barrington, Basking Ridge, Bay Shore, Beachwood, Bellingham, Bend, Bethesda, Bethlehem, Beverly Hills, Billings, Birmingham, Bloomington, Bluffton, Boise, Boston, Bozeman, Bradenton, Bridgeport, Brighton, Brightwaters, Bryn Mawr, Buena Park, Burbank, Burlington, Burnsville, Butte, Caldwell, Cambridge, Camden, Canton, Carmel, Carmichael, Cary, Centerville, Centralia, Chadds Ford, Chapel Hill, Chardon, Charleston, Charlotte, Charlottesville, Chaska, Chelsea, Chicago, Cincinnati, Clackamas, Clarkston, Clearwater, Clemmons, Cleveland, Colorado Springs, Columbus, Commack, Concord, Coon Rapids, Coos Bay, Coral Gables, Corbin, Council Bluffs, Crown Point, Crystal Lake, Cudahy, Dallas, Danbury, Danville, Dayton, Dearborn, Decatur, Deerfield Beach, DeKalb, Delaware, Detroit, Doral, Downers Grove, Duarte, Dublin, Durham, East China Township, East Stroudsburg, Edgewood, Edina, Edmonds, Effingham, Elgin, Elizabethtown, Elk Grove, Elkin, Elkton, Elmhurst, Englewood, Evanston, Everett, ‘Ewa Beach, Fairfax, Fairway, Falls Church, Farmington Hills, Flint, Flushing, Fort Collins, Fort Lauderdale, Fort Myers, Fort Sam Houston, Franklin, Fremont, Fresno, Fridley, Fruitland, Gaffney, Gainesville, Geneva, Germantown, Gladwin, Glen Burnie, Glen Cove, Glenview, Goodyear, Goshen, Grafton, Grand Rapids, Grayslake, Greeley, Green Bay, Greenville, Greenwich, Greer, Grosse Pointe Woods, Harrison, Hartford, Hazel Crest, Hazleton, Hershey, Highland Park, Highlands Ranch, High Point, Hinsdale, Honolulu, Hood River, Houston, Huntington, Huntington Beach, Indianapolis, Iowa City, Irvine, Issaquah, Jefferson Hills, Jersey City, Kalamazoo, Kansas City, Kearney, Kennewick, Kenosha, Lacey, Lake Forest, Lake Success, Lancaster, Lansing, Las Vegas, Lebanon, Lewes, Lexington, Libertyville, Lihue, Little Rock, Livingston, Livonia, Longmont, Longview, Los Angeles, Louisville, Loveland, Macomb, Madison, Madisonville, Manhasset, Mansfield, Maple Grove, Maplewood, Marinette, Marion, Marrero, Marshfield, Martinsburg, Mattoon, Mayfield Heights, Mentor, Meridian, Miami, Middletown, Midland, Milwaukee, Mineola, Minneapolis, Missoula, Modesto, Monroeville, Monticello, Montvale, Morgantown, Morristown, Mount Airy, Mount Holly, Mount Kisco, Mount Pleasant, Mount Vernon, Mukwonago, Muskegon, Nampa, Napa, Naperville, Nashville, Natrona Heights, New Albany, Newark, Newberg, New Britain, New Brunswick, New Haven, New Hyde Park, New Lenox, Newnan, New Orleans, Newport Beach, New Richmond, New Ulm, New York, Nokomis, Normal, North Kansas City, North Miami, Norton Shores, Norwalk, Oakland, Oak Lawn, Oak Park, Oconomowoc, Oklahoma City, Omaha, Ontario, Oregon City, Orland Park, Oshkosh, Overland Park, Paducah, Panorama City, Paoli, Parkersburg, Park Ridge, Parma, Pasadena, Pennington, Philadelphia, Pickerington, Pittsburgh, Plainfield, Plainsboro, Plantation, Pontiac, Portland, Poughkeepsie, Princeton, Providence, Racine, Raleigh, Rancho Cordova, Redmond, Redwood City, Rego Park, Rehoboth Beach, Richmond, Rio Rancho, Riverside, Roanoke, Robbinsdale, Rochester, Rocklin, Rohnert Park, Roseville, Royal Oak, Sacramento, Saginaw, Saint Louis Park, Saint Paul, Salt Lake City, San Antonio, San Francisco, San Jose, San Leandro, San Rafael, Santa Clara, Santa Rosa, Sarasota, Savannah, Scarborough, Seattle, Sedro-Woolley, Seneca, Sewell, Shakopee, Sheboygan, Shelton, Shreveport, Sioux Falls, Sleepy Hollow, Somerville, South Pasadena, South San Francisco, Spartanburg, Spokane, Springfield, Statesville, Sterling Heights, Stillwater, St Louis, Stockton, Stony Brook, St. Petersburg, Summit, Sylvania, Syracuse, Tampa, Tawas City, Toledo, Torrance, Troy, Tualatin, Tucson, Twin Falls, Two Rivers, Union, Uniondale, Upland, Urbana, Vacaville, Vallejo, Vancouver, Venice, Voorhees Township, Waconia, Walla Walla, Walnut Creek, Warren, Warrenville, Washington D.C., Waterford, Waukesha, Wauwatosa, Webster, West Allis, West Chester, Westerville, Westlake, Westwood, Wexford, Wheeling, Wilkesboro, Willmar, Willow Grove, Wilmington, Winston-Salem, Woodbury, Woodland, Wynnewood, Wyoming, Yelm, Yorkville, Ypsilanti, Zion
Age
35 years to 50 years
People
1,956 worldwide
Run by
NRG Oncology
See details and how to joinNCT04251052
Phase 2Taking people
At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer
Where
Grand Forks, Jacksonville
Age
18 years and over
People
220
Run by
Mayo Clinic
See details and how to joinNCT05969860
No phaseTaking people
Clonal Hematopoiesis and Therapy-Emergent Myeloid Neoplasms in Patients With Cancers, CHANCES Study
Where
Seattle
People
2,000
Run by
University of Washington
See details and how to joinNCT06295965
Phase 2Taking people
Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer
Where
Birmingham, Boston, Chicago, Dallas, Detroit, Hilliard, Jacksonville, La Jolla, Los Angeles, Louisville, Madison, Miami, Milwaukee, Orlando, Pittsburgh, Portland, Seattle, Sioux Falls, Tampa, Westwood
Age
18 years and over
People
397 worldwide
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT06787612 · EU 2024-517806-27-00
No phaseTaking people
The Vanguard Study: Testing a New Way to Screen for Cancer
Where
Bethesda, Brownstown, Chapel Hill, Charlottesville, Chesterfield, Cheyenne Wells, Cleveland, Clinton Township, Dearborn, Denver, Detroit, Durham, Fairfax, Fort Collins, Greeley, Grosse Pointe Farms, Honolulu, Kansas City, Lafayette, Livonia, Lone Tree, Loveland, Milwaukee, Minneapolis, Norfolk, Novi, Oklahoma City, Pleasanton, Plymouth, Portsmouth, Richmond, Royal Oak, San Diego, South Hill, Springfield, Sterling Heights, St Louis, Tacoma, Troy, West Bloomfield, Wyandotte
Age
45 years to 75 years
People
24,000
Run by
National Cancer Institute (NCI)
See details and how to joinNCT06995898
Phase 3Taking people
Torvutatug Samrotecan Plus Bevacizumab as First-line Maintenance in Non-Homologous Recombination Deficiency (Non-HRD) Positive Advanced Epithelial Ovarian Cancer
Where
Baltimore, Baton Rouge, Billings, Cleveland, Tamarac, Tampa
Age
18 years and over
People
950 worldwide
Run by
AstraZeneca
See details and how to joinNCT07851025 · EU 2026-526895-22-00
No phaseTaking people
Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma
Where
Bethesda
Age
2 years to 100 years
People
1,000
Run by
National Cancer Institute (NCI)
See details and how to joinNCT01950572
Phase 2Taking people
Immunotherapy Platform Study in Platinum Resistant High Grade Serous Ovarian Cancer
Where
Chicago
Age
18 years and over
People
60 worldwide
Run by
Canadian Cancer Trials Group
See details and how to joinNCT04918186
No phaseTaking people
Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer
Where
Atlanta, Chicago, Cleveland, Detroit, Eau Claire, Evergreen Park, Grand Forks, Houston, Howard Beach, Jackson, Jacksonville, Katy, La Crosse, Miami, Milwaukee, New Orleans, Orlando, Pembroke Pines, Phoenix, Richmond, Rochester, Saginaw, Sarasota, Westbury
Age
18 years and over
People
3,110
Run by
Mayo Clinic
See details and how to joinNCT05051722
Phase 1Taking people
A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors
Where
Atlanta, Augusta, Austin, Boston, Charlottesville, Dallas, Denver, Fairfax, Fairway, Hackensack, Lake Mary, Little Rock, Los Angeles, Nashville, Orlando, Philadelphia, Pittsburgh, Salt Lake City, San Francisco
Age
19 years and over
People
238 worldwide
Run by
NiKang Therapeutics, Inc.
See details and how to joinNCT06586957
Phase 1Taking people
Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma
Where
Bethesda
Age
18 years to 120 years
People
120
Run by
National Cancer Institute (NCI)
See details and how to joinNCT06885697
No phaseTaking people
INtegrating Systematic PatIent-Reported Evaluations in Multi-Disciplinary Tumor Boards: The INSPIRE Study
Where
Birmingham, Los Angeles, Oklahoma City
Age
18 years and over
People
2,748
Run by
University of Alabama at Birmingham
See details and how to joinNCT07671937
Phase 3Taking people
A Study of Raludotatug Deruxtecan With or Without Bevacizumab as First-Line Maintenance Treatment in Non-HRD-Positive Advanced Ovarian Cancer (MK-5909-006, (ENGOT-ov102/GOG-3141/ REJOICE-Ovarian 04)
Where
Amarillo, Austin, Burlington, Eugene, Fort Worth, Tyler, Washington D.C.
Age
18 years and over
People
802 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT07776691 · EU 2025-524592-22-00
Phase 1Not yet taking people in United States
A Project Assessing the Safety and Feasibility of Using Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Ovarian Cancer During Surgical Procedures
Where
Birmingham
Age
18 years and over
People
6
Run by
University of Alabama at Birmingham
See details and how to joinNCT07919509
Phase 1Taking people
Testing the Addition of Abemaciclib to Olaparib for Women With Recurrent Ovarian Cancer
Where
Charlottesville, Chicago, Columbus, Coral Gables, Deerfield Beach, Fairway, Irvine, Jacksonville, Kansas City, Lee's Summit, Los Angeles, Miami, Nashville, New York, North Kansas City, Oklahoma City, Orange, Overland Park, Philadelphia, Phoenix, Plantation, Rochester, Westwood, Winston-Salem
Age
18 years and over
People
42
Run by
National Cancer Institute (NCI)
See details and how to joinNCT04633239