Pancreatic cancer trials in Canada

In Canada 58 Also abroad 1095

58 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)
Where
Calgary, Toronto
Age
12 years and over
People
355 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT04924075 · EU 2023-504853-11-00
No phaseTaking people
EUS-CPN With and Without Bupivacaine
Where
Montreal
Age
18 years and over
People
180
Run by
Centre hospitalier de l'Université de Montréal (CHUM)
See details and how to joinNCT04951804
Phase 1Taking people
A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors
Where
Toronto
Age
18 years to 99 years
People
600 worldwide
Run by
Erasca, Inc.
See details and how to joinNCT06983743 · EU 2026-525794-39-00
Phase 2Taking people
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer
Where
Toronto
Age
18 years and over
People
185 worldwide
Run by
Verastem, Inc.
See details and how to joinNCT07644559
Phase 1Taking people
A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors
Where
Montreal, Toronto
Age
18 years and over
People
540 worldwide
Run by
Pfizer
See details and how to joinNCT07090499 · EU 2025-521729-33-00
Phase 2Taking people
A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
Where
Halifax, Montreal, Toronto
Age
18 years and over
People
111 worldwide
Run by
Bayer
See details and how to joinNCT06760819 · EU 2024-517419-62-00
Phase 2Taking people
A Study of Navlimetostat (BMS-986504) Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)
Where
Toronto, Vancouver
Age
18 years and over
People
254 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT07492680
Phase 1Taking people
M0324 as Monotherapy and in Combination With Pembrolizumab or Chemotherapy in Participants With Selected Advanced Solid Tumors
Where
Toronto
Age
18 years and over
People
77 worldwide
Run by
EMD Serono Research & Development Institute, Inc.
See details and how to joinNCT07166601
Phase 2/3Taking people
Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors
Where
London, Ottawa, Toronto
Age
18 years and over
People
440 worldwide
Run by
Exelixis
See details and how to joinNCT06943755 · EU 2025-521043-20-00
No phaseTaking people
Mainstreaming Genetics: Evaluation of a Digital Application to Scale and Spread Oncologist-initiated Genetic Testing
Where
Toronto
Age
18 years and over
People
180
Run by
Unity Health Toronto
See details and how to joinNCT07387263
Phase 3Taking people
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
Where
Hamilton, Kingston, Montreal, Québec, Toronto
Age
18 years and over
People
588 worldwide
Run by
Incyte Corporation
See details and how to joinNCT07522073
No phaseTaking people
Pancreatic Cancer Early Detection Consortium
Where
Montreal, Toronto, Vancouver
Age
18 years to 90 years
People
20,000 worldwide
Run by
Arbor Research Collaborative for Health
See details and how to joinNCT04970056
Phase 1/2Taking people
A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)
Where
Montreal, Ottawa
Age
18 years and over
People
220 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06428409 · EU 2023-508703-21-00
Phase 1/2Taking people
BOLD-100 in Combination With FOLFOX With or Without Bevacizumab for the Treatment of Advanced, Solid Tumours
Where
Edmonton, Hamilton, Montreal, Ottawa, Toronto
Age
18 years and over
People
220 worldwide
Run by
Bold Therapeutics, Inc.
See details and how to joinNCT04421820 · EU 2024-517500-11-00
Phase 2Taking people
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Where
Edmonton, Toronto, Vancouver
Age
18 years and over
People
740 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06172478 · EU 2023-507641-29-00
Phase 3Taking people
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
Where
Montreal, Toronto
Age
18 years and over
People
500 worldwide
Run by
Revolution Medicines, Inc.
See details and how to joinNCT07252232 · EU 2025-523495-23-00
Phase 1Taking people
Testing the Addition of Sunitinib Malate to Lutetium Lu 177 Dotatate (Lutathera) in Pancreatic Neuroendocrine Tumors
Where
Toronto
Age
18 years and over
People
24 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT05687123
Phase 1Taking people
Anti-Ly6E Exatecan ADC M7437 in Advanced Solid Tumors
Where
Toronto, Vancouver
Age
18 years and over
People
138 worldwide
Run by
EMD Serono Research & Development Institute, Inc.
See details and how to joinNCT07360314 · EU 2025-523232-39-00
Phase 1/2Taking people
A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed (EMBOLD PanGI-201)
Where
Calgary, Montreal, Sherbrooke, Toronto
Age
18 years and over
People
346 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT06885034
Phase 2/3Taking people
A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
Where
Calgary, Chicoutimi, Greenfield Park, Montreal, Ottawa, Toronto
Age
18 years and over
People
982 worldwide
Run by
Pfizer
See details and how to joinNCT06989437 · EU 2025-522093-36-00
Phase 1Taking people
Phase I Study of [177Lu]Lu-DFC413 in Patients With Solid Tumors
Where
Montreal
Age
18 years and over
People
180 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07261631
Phase 1Taking people
Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
Where
Montreal, Toronto
Age
18 years and over
People
473 worldwide
Run by
Bicara Therapeutics
See details and how to joinNCT04429542
Phase 3Taking people
Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
Where
Montreal, Toronto
Age
18 years and over
People
900 worldwide
Run by
Revolution Medicines, Inc.
See details and how to joinNCT07491445 · EU 2025-525088-34-00
Phase 2Taking people
AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2
Where
Kingston, Montreal, Sherbrooke, Toronto
Age
18 years and over
People
226 worldwide
Run by
AstraZeneca
See details and how to joinNCT06219941 · EU 2023-508275-37-00
No phaseTaking people
Using Tumour DNA and Proteins to Better Understand How Pancreatic Cancer Responds to Treatment
Where
Vancouver
Age
18 years and over
People
200
Run by
British Columbia Cancer Agency
See details and how to joinNCT06574620