Pancreatic cancer trials in United Kingdom

In United Kingdom 56 Also abroad 1095

56 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)
Where
Cambridge, Glasgow, London
Age
12 years and over
People
355 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT04924075 · EU 2023-504853-11-00
Phase 3Taking people
Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
Where
Coventry, London, Manchester
Age
18 years and over
People
570 worldwide
Run by
Immuneering Corporation
See details and how to joinNCT07562152 · EU 2026-525617-31-00
Phase 3Taking people
Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 )
Where
London
Age
18 years and over
People
670 worldwide
Run by
Revolution Medicines, Inc.
See details and how to joinNCT07621718
Phase 1Taking people
A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors
Where
London, Manchester
Age
18 years and over
People
540 worldwide
Run by
Pfizer
See details and how to joinNCT07090499 · EU 2025-521729-33-00
Phase 1/2Taking people
A 2-part Phase 1/2 Open-label Trial on ODM-212
Where
Leicester, London, Southampton
Age
18 years and over
People
229 worldwide
Run by
Orion Corporation, Orion Pharma
See details and how to joinNCT07563738
Phase 1Taking people
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
Where
London, Manchester
Age
18 years and over
People
460 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT06465069 · EU 2024-512927-36-00
Phase 3Taking people
A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
Where
Cambridge, Cottingham, Ipswich, London, Maidstone, Sutton
Age
18 years and over
People
614 worldwide
Run by
Astellas Pharma Global Development, Inc.
See details and how to joinNCT07409272 · EU 2025-523684-38-00
Phase 2/3Taking people
Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors
Where
Birmingham, Cardiff, Glasgow, Liverpool, London, Oxford, Sheffield, Sutton, Swansea
Age
18 years and over
People
440 worldwide
Run by
Exelixis
See details and how to joinNCT06943755 · EU 2025-521043-20-00
Phase 3Taking people
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
Where
Dundee, Guildford, Headington, Leeds, London, Manchester, Northwood, Norwich
Age
18 years and over
People
588 worldwide
Run by
Incyte Corporation
See details and how to joinNCT07522073
No phaseTaking people
Pancreatic Cancer Early Detection Consortium
Where
Liverpool
Age
18 years to 90 years
People
20,000 worldwide
Run by
Arbor Research Collaborative for Health
See details and how to joinNCT04970056
Phase 1/2Taking people
A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)
Where
Coventry, London
Age
18 years and over
People
220 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06428409 · EU 2023-508703-21-00
Phase 1/2Taking people
BOLD-100 in Combination With FOLFOX With or Without Bevacizumab for the Treatment of Advanced, Solid Tumours
Where
Cardiff, Dundonald, London, Sutton
Age
18 years and over
People
220 worldwide
Run by
Bold Therapeutics, Inc.
See details and how to joinNCT04421820 · EU 2024-517500-11-00
Phase 1Taking people
A Study of MGC026 in Participants With Advanced Solid Tumors
Where
Oxford, Sutton
Age
18 years and over
People
394 worldwide
Run by
MacroGenics
See details and how to joinNCT06242470
Phase 1/2Taking people
A Study of PRMT5 Inhibitor BAY 3713372 in Participants With MTAP-deleted Solid Tumors
Where
Manchester, Sutton
Age
18 years and over
People
450 worldwide
Run by
Bayer
See details and how to joinNCT06914128 · EU 2025-520623-24-00
Phase 2Taking people
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Where
Cambridge, Coventry, London, Nottingham
Age
18 years and over
People
740 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06172478 · EU 2023-507641-29-00
Phase 3Taking people
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
Where
Birmingham, Glasgow, Liverpool, London, Manchester
Age
18 years and over
People
500 worldwide
Run by
Revolution Medicines, Inc.
See details and how to joinNCT07252232 · EU 2025-523495-23-00
Phase 1/2Taking people
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
Where
Glasgow, London, Manchester
Age
18 years and over
People
542 worldwide
Run by
Artios Pharma Ltd
See details and how to joinNCT04657068
No phaseTaking people
Breath Research Narrow Validation for Gastrointestinal Cancer Detection
Where
Glasgow, Liverpool, London, Maidstone
Age
18 years and over
People
1,000
Run by
Imperial College London
See details and how to joinNCT07714538
Phase 1/2Taking people
A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed (EMBOLD PanGI-201)
Where
Manchester
Age
18 years and over
People
346 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT06885034
Phase 1/2Taking people
A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9
Where
Leeds, London, Manchester, Newcastle upon Tyne, Sutton
Age
18 years and over
People
245 worldwide
Run by
BioNTech SE
See details and how to joinNCT07186842 · EU 2025-522613-26-00
Phase 2/3Taking people
A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
Where
Cambridge, Edinburgh, Liverpool, London
Age
18 years and over
People
982 worldwide
Run by
Pfizer
See details and how to joinNCT06989437 · EU 2025-522093-36-00
Phase 2Taking people
Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer
Where
Cambridge, Hammersmith, Sutton
Age
18 years and over
People
25 worldwide
Run by
EXACT Therapeutics AS
See details and how to joinNCT06850623
Phase 1/2Taking people
Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
Where
Glasgow, Scotland, London, Newcastle upon Tyne
Age
18 years to 130 years
People
695 worldwide
Run by
AstraZeneca
See details and how to joinNCT05417594 · EU 2023-504984-17-00
Phase 3Taking people
Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
Where
Birmingham, Cambridge, Liverpool, London, Manchester, Torquay
Age
18 years and over
People
900 worldwide
Run by
Revolution Medicines, Inc.
See details and how to joinNCT07491445 · EU 2025-525088-34-00
Phase 1/2Taking people
HTL0039732 in Participants With Advanced Solid Tumours
Where
Cambridge, Cardiff, Dundee, Liverpool, London, Manchester
Age
18 years and over
People
150
Run by
Cancer Research UK
See details and how to joinNCT05944237