Pancreatic cancer trials in Netherlands

In Netherlands 49 Also abroad 1095

49 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)
Where
Utrecht
Age
12 years and over
People
355 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT04924075 · EU 2023-504853-11-00
Phase 3Taking people
Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 )
Where
Nijmegen
Age
18 years and over
People
670 worldwide
Run by
Revolution Medicines, Inc.
See details and how to joinNCT07621718
Phase 1Taking people
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
Where
Amsterdam, Maastricht, Nijmegen, Utrecht
Age
18 years and over
People
340 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07213791 · EU 2025-521887-37-00
Phase 2/3Taking people
Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors
Where
Amsterdam, Maastricht, Veldhoven
Age
18 years and over
People
440 worldwide
Run by
Exelixis
See details and how to joinNCT06943755 · EU 2025-521043-20-00
Phase 3Taking people
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
Where
Amsterdam, Eindhoven, Groningen, Maastricht, Utrecht
Age
18 years and over
People
588 worldwide
Run by
Incyte Corporation
See details and how to joinNCT07522073
Phase 1/2Taking people
A Study of PRMT5 Inhibitor BAY 3713372 in Participants With MTAP-deleted Solid Tumors
Where
Amsterdam, Groningen, Rotterdam
Age
18 years and over
People
450 worldwide
Run by
Bayer
See details and how to joinNCT06914128 · EU 2025-520623-24-00
Phase 3Taking people
Timing of start of systemlc treatment for asymptomatic MEtastasized PANcreatic cancer (TIMEPAN): a prospective multicenter patient preference cohort
Where
Amersfoort, Amsterdam, Enschede, Harderwijk, Hoofddorp, Hoorn Nh, Leiden, Maastricht, Rotterdam, 'S-Hertogenbosch, Utrecht
Age
18 years and over
People
184
Run by
Amsterdam UMC
See details and how to joinNCT04897854 · EU 2023-509465-20-00
Phase 2Taking people
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Where
Amsterdam, Groningen, Leiden, Maastricht, Nijmegen
Age
18 years and over
People
740 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06172478 · EU 2023-507641-29-00
Phase 1/2Taking people
A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)
Where
Amsterdam, Groningen, Nijmegen, Rotterdam, Utrecht
Age
18 years and over
People
680 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06330064 · EU 2023-509632-26-00
Phase 3Not yet taking people in Netherlands
Phase 3 Study of Zoldonrasib (RMC-9805) Plus Daraxonrasib (RMC 6236) Versus Gemcitabine and Nab-Paclitaxel as First-Line Treatment in Metastatic KRAS G12D-Mutated Pancreatic Adenocarcinoma
Where
Amsterdam, Maastricht
Age
18 years and over
People
233 worldwide
Run by
Revolution Medicines Inc.
See details and how to join2025-524969-24-00 · EU 2025-524969-24-00
No phaseTaking people
Preoperative Optimisation of Modifiable Risk Factors in Surgery of the Pancreas
Where
Amsterdam, Breda, Eindhoven, Enschede, Groningen, Leeuwarden, Leiden, Maastricht, Nijmegen, Rotterdam, 's-Hertogenbosch, Utrecht
Age
18 years and over
People
2,575
Run by
Maastricht University Medical Center
See details and how to joinNCT05851534
Phase 1/2Taking people
A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed (EMBOLD PanGI-201)
Where
Amsterdam, Maastricht, Rotterdam, Utrecht
Age
18 years and over
People
346 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT06885034
Phase 1Not yet taking people in Netherlands
PANVIRAL: Safety, Feasibility and Immunogenicity of Intra-Tumoral ORCA-010 Oncolytic Virus Administration in Metastatic Pancreatic Cancer – A Single-Center Phase 1 Trial
Where
Amsterdam
Age
18 years and over
People
15
Run by
Amsterdam UMC Stichting
See details and how to join2026-527268-33-00 · EU 2026-527268-33-00
Phase 3Taking people
Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
Where
Amsterdam, Nieuwegein, Rotterdam
Age
18 years and over
People
900 worldwide
Run by
Revolution Medicines, Inc.
See details and how to joinNCT07491445 · EU 2025-525088-34-00
Phase 3Taking people
A clinical trial of belzutifan and other treatments in people with solid tumors or von Hippel-Lindau (VHL)-related tumors (MK-6482-043)
Where
Amsterdam, Maastricht, Zwolle
Age
18 years and over
People
134 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to join2025-524160-38-00 · EU 2025-524160-38-00
Phase 3Taking people
Phase 3 Study of Investigator Choice of Chemotherapy with or without Zoldonrasib as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma
Where
Amsterdam, Leeuwarden, Nijmegen
Age
18 years and over
People
281 worldwide
Run by
Revolution Medicines Inc.
See details and how to join2025-524928-21-00 · EU 2025-524928-21-00
Phase 3Taking people
A Randomized, Double-Blind, Phase 3 Study of Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D–Mutated Metastatic Pancreatic Ductal Adenocarcinoma (DAWN-303)
Where
Amsterdam, Eindhoven, Groningen, Maastricht, Nieuwegein
Age
18 years and over
People
239 worldwide
Run by
Incyte Corp.
See details and how to join2025-525009-18-00 · EU 2025-525009-18-00
Phase 1/2Taking people
Study of AZD5863 in Adult Participants With Advanced or Metastatic Solid Tumors
Where
Amsterdam, Groningen, Rotterdam
Age
18 years and over
People
392 worldwide
Run by
AstraZeneca
See details and how to joinNCT06005493 · EU 2023-504139-42-00
Phase 2Not yet taking people in Netherlands
A Phase 2 Study to Evaluate the Efficacy and Safety of Ampligen® Compared to Control Group / No Treatment Following FOLFIRINOX in Subjects with Locally Advanced Pancreatic Adenocarcinoma
Where
Rotterdam
Age
18 years and over
People
30
Run by
Aim Immunotech Inc.
See details and how to joinNCT05494697 · EU 2024-518627-29-00
Phase 1/2Taking people
Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
Where
Amsterdam
Age
18 years and over
People
534 worldwide
Run by
Revolution Medicines, Inc.
See details and how to joinNCT06128551
Phase 4Taking people
Preventing postoperative complications in patients undergoing high-risk pancreatoduodenectomy with a bundle approach including hydrocortisone, ocreotide, and teres ligament patch (PANENCA): an international randomized controlled multicenter trial
Where
Amsterdam, Eindhoven, Enschede, Groningen, Leiden, Maastricht, Nijmegen, Rotterdam, 'S-Hertogenbosch, Utrecht, Zwolle
Age
18 years and over
People
460 worldwide
Run by
Amsterdam UMC Stichting
See details and how to join2024-519667-18-00 · EU 2024-519667-18-00
Phase 2Taking people
[68Ga]BED003 PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications
Where
Groningen, Nijmegen
Age
18 years to 79 years
People
71 worldwide
Run by
Blue Earth Diagnostics
See details and how to joinNCT07702292 · EU 2025-521983-36-00
Phase 1/2Taking people
Master protocol of TCR-modified T cell therapy targeting HLA-restricted KRAS antigen administered in adult patients with metastatic or locally advanced PDAC
Where
Amsterdam, Nijmegen
Age
18 years and over
People
57 worldwide
Run by
Anocca AB
See details and how to join2024-513900-32-00 · EU 2024-513900-32-00
No phaseNot yet taking people in Netherlands
Spleen Preservation Versus Splenectomy in Left Pancreatectomy for Pancreatic Ductal Adenocarcinoma (SPLENDID)
Where
Amsterdam
Age
18 years and over
People
360
Run by
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
See details and how to joinNCT07799298
Phase 1Taking people
AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors
Where
Utrecht
Age
18 years and over
People
434 worldwide
Run by
Amgen
See details and how to joinNCT07094113