Parkinson disease trials in United States

In United States 294 Also abroad 869

294 trials · From ClinicalTrials.gov, checked 14 November 2026. Ask the study team whether a trial fits you.

Early phase 1Taking people
Bayesian Optimization of DBS for Gait
Where
Minneapolis
Age
18 years and over
People
15
Run by
University of Minnesota
See details and how to joinNCT07835308
No phaseTaking people
Velocity-Loss Training and Parkinson's Disease
Where
Coral Gables
Age
50 years to 85 years
People
60
Run by
University of Miami
See details and how to joinNCT07840508
No phaseTaking people
GBPDC: Gut-Brain in PD Consortium Master Protocol
Where
Boston, Charleston, Chicago, New York, Rochester, Stanford
Age
21 years to 80 years
People
250
Run by
Duke University
See details and how to joinNCT07567794
No phaseTaking people
Speech Learning and Speech Production in Parkinson's Disease
Where
Buffalo
Age
45 years and over
People
50
Run by
State University of New York at Buffalo
See details and how to joinNCT07403539
Phase 2Taking people
Low-dose Carbon Monoxide (HBI-002) Trial to Evaluate Safety, Tolerability, PK, and Biomarkers in Parkinson's Disease
Where
Ann Arbor, Boston, East Lansing, Farmington Hills, Fountain Valley, Gainesville, New York, Spokane
Age
40 years to 80 years
People
36
Run by
Hillhurst Biopharmaceuticals, Inc.
See details and how to joinNCT07005180
Phase 2Taking people
This Protocol is a Sub-study Under the PPMI Program. It is a Longitudinal, Single-center Study to Assess the Performance of [18F]AV-133 Imaging Using High and Standard Resolution PET in Individuals Enrolled With Parkinson's Disease (PD) for up to 12 Months.
Where
New Haven
Age
18 years and over
People
50
Run by
Michael J. Fox Foundation for Parkinson's Research
See details and how to joinNCT07830654
No phaseTaking people
Natural History Protocol for Movement Disorders
Where
Bethesda
Age
2 years to 100 years
People
4,000
Run by
National Institute of Neurological Disorders and Stroke (NINDS)
See details and how to joinNCT05413291
Phase 2Taking people
RESvEraTrol in Parkinson's Disease (RESET)
Where
Washington D.C.
Age
55 years to 85 years
People
30
Run by
Georgetown University
See details and how to joinNCT07592767
Phase 1/2Taking people
ATR 1072 in Participants With PRKAG2 Syndrome
Where
Kansas City
Age
18 years to 65 years
People
37
Run by
Atrium Therapeutics
See details and how to joinNCT07738107
No phaseTaking people
Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor
Where
Nashville
Age
18 years and over
People
60
Run by
Vanderbilt University Medical Center
See details and how to joinNCT01734122
Phase 1Enrolling by invitation
Autologous iPSC-Derived Dopamine Neuron Transplantation for Parkinson's Disease
Where
Boston
Age
55 years to 80 years
People
12
Run by
Penelope J. Hallett, Ph.D.
See details and how to joinNCT06422208
No phaseTaking people
Dual Frequency Stimulation in Parkinson's Disease
Where
Sacramento
Age
18 years and over
People
10
Run by
University of California, Davis
See details and how to joinNCT04650932
No phaseTaking people
Simplified, Scalable, 24-hour Adaptive DBS in Parkinson's Disease
Where
San Francisco
Age
18 years and over
People
24
Run by
University of California, San Francisco
See details and how to joinNCT07398157
No phaseTaking people
Automated Daytime Adaptive Deep Brain Stimulation Parameter Optimization in Patients Implanted With Percept Neurostimulator
Where
San Francisco
Age
25 years to 75 years
People
40
Run by
University of California, San Francisco
See details and how to joinNCT07682311
No phaseNot yet taking people in United States
Gamification and Physical Activity in PD
Where
Philadelphia
Age
50 years to 89 years
People
110
Run by
VA Office of Research and Development
See details and how to joinNCT07286994
No phaseEnrolling by invitation
Parkinson's Improvement Activated by Hula Understanding (PAHU) - Part 2
Where
Honolulu
Age
18 years and over
People
40
Run by
University of Hawaii
See details and how to joinNCT07808606
Phase 2Taking people
A Comparative Performance Study Between High and Standard Resolution Positron Emission Tomography Camera Using [18F] AV-133 in Prodromal Parkinson's Disease
Where
New Haven
Age
18 years and over
People
25
Run by
Michael J. Fox Foundation for Parkinson's Research
See details and how to joinNCT07809438
No phaseTaking people
Parkinson's Foundation PD GENEration Genetic Registry
Where
Albuquerque, Ann Arbor, Atlanta, Aurora, Aventura, Baltimore, Birmingham, Boca Raton, Boston, Chandler, Chapel Hill, Charleston, Charlotte, Chicago, Cincinnati, Cleveland, College Park, Colombus, Evanston, Farmington, Fayetteville, Gainesville, Golden Valley, Hartford, Honolulu, Houston, Indianapolis, Iowa City, Kirkland, La Jolla, Las Vegas, Lawrence, Lexington, Los Angeles, Miami, Milwaukee, Murray, Nashville, New Brunswick, New York, Philadelphia, Phoenix, Pittsburgh, Portland, Redwood City, Richmond, Rochester, San Antonio, San Francisco, Shreveport, Spokane, Weston
Age
18 years and over
People
35,382 worldwide
Run by
Parkinson's Foundation
See details and how to joinNCT04994015
No phaseTaking people
Parkinson Progression Marker Initiative Online (PPMI Online)
Where
San Francisco
Age
18 years and over
People
500,000
Run by
Michael J. Fox Foundation for Parkinson's Research
See details and how to joinNCT05065060
No phaseTaking people
A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications
Where
Ann Arbor, Atlanta, Augusta, Boston, Burlington, Charlottesville, Cleveland, Fountain Valley, Houston, Los Angeles, Miami, Murray, New Brunswick, New Haven, New York, Norfolk, Olney, Orlando, Philadelphia, Phoenix, Seattle, Stony Brook, Tampa, Tucson, Williamsville, Winfield
Age
45 years to 75 years
People
300
Run by
Bayer
See details and how to joinNCT07330258
No phaseEnrolling by invitation
Effect on Parkinson's Disease After Therapeutic Induction of CranioSacral Integrated Therapy
Where
Ann Arbor
Age
18 years and over
People
5
Run by
Zia, Al Raza
See details and how to joinNCT01989013
Phase 4Taking people
Cortical Electrophysiology of Response Inhibition in Parkinson's Disease
Where
Atlanta
Age
45 years to 75 years
People
80
Run by
Emory University
See details and how to joinNCT06234995
No phaseEnrolling by invitation
Connectomic Guided DBS for Parkinson's Disease
Where
Durham
Age
18 years and over
People
20
Run by
Duke University
See details and how to joinNCT06618157
No phaseTaking people
Optimizing Adaptive DBS for Parkinson's Disease
Where
Davis
Age
18 years and over
People
35
Run by
University of California, Davis
See details and how to joinNCT07798271
No phaseTaking people
Biofluid Research on Age-Related or Inherited Neurodegeneration
Where
Philadelphia
Age
18 years and over
People
1,000
Run by
University of Pennsylvania
See details and how to joinNCT07798700