Parkinson disease trials in United States

In United States 294 Also abroad 869

294 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

Phase 1Taking people
Autologous suraL nervE Grafting to the Substantia nigrA in Patients With Synuclienopathies
Where
Lexington
Age
40 years to 75 years
People
7
Run by
Craig van Horne, MD, PhD
See details and how to joinNCT06683365
Phase 1Taking people
A Study to Evaluate Feasibility, Safety, and Clinical Responses of Implanting Autologous Peripheral Nerve Tissue Into the Brain for Non-motor or Motor Symptoms in Patients With Parkinson's Disease Undergoing DBS Surgery
Where
Lexington
Age
45 years to 75 years
People
24
Run by
Craig van Horne, MD, PhD
See details and how to joinNCT06683378
No phaseTaking people
Deep Brain Stimulation Neural Recordings of Varied Stimulation During Sleep in Parkinson's Disease
Where
Cleveland
Age
18 years and over
People
10
Run by
The Cleveland Clinic
See details and how to joinNCT07110376
Phase 4Not yet taking people in United States
Gastrointestinal Dopamine Decarboxylase and Levodopa Pharmacokinetics
Where
Boston
People
40
Run by
Beth Israel Deaconess Medical Center
See details and how to joinNCT07793461
No phaseTaking people
Physiological Brain Atlas Development
Where
Nashville
Age
6 years to 90 years
People
5,000
Run by
Vanderbilt University Medical Center
See details and how to joinNCT00575081
No phaseTaking people
Correlation of STN-DBS Induced Visuospatial Changes and Freezing of Gait
Where
Charleston
Age
18 years and over
People
12
Run by
Medical University of South Carolina
See details and how to joinNCT06994728
No phaseTaking people
A Novel Digital Music-based Autonomous Personalized Walking Intervention to Improve Gait and Walking Automaticity in Parkinson Disease
Where
Boston, Salt Lake City, St Louis
Age
40 years and over
People
200
Run by
Boston University Charles River Campus
See details and how to joinNCT07705373
No phaseTaking people
Cross-System Effects of Acute Intermittent Hypercapnia-Based Interventions in PD
Where
Gainesville
Age
40 years to 75 years
People
32
Run by
University of Florida
See details and how to joinNCT07674264
Phase 4Taking people
Personalized Real-Time DBS and PD Mechanisms
Where
Cleveland
Age
18 years to 80 years
People
25
Run by
David Escobar
See details and how to joinNCT06013956
Phase 4Taking people
Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis
Where
Albuquerque, Ann Arbor, Asheville, Aurora, Cleveland, Gainesville, Hines, Houston, Lexington, Loma Linda, Minneapolis, Nashville, Palo Alto, Philadelphia, Portland, Richmond, San Antonio, San Francisco, Seattle, St Louis, Syracuse, Tucson, West Los Angeles
Age
40 years and over
People
358
Run by
VA Office of Research and Development
See details and how to joinNCT04373317
Phase 1Taking people
Transplantation of Human iPS Cell-derived Dopaminergic Progenitors (CT1-DAP001) for Parkinson's Disease (Phase I/II)
Where
La Jolla
Age
40 years to 75 years
People
7
Run by
University of California, San Diego
See details and how to joinNCT06482268
No phaseNot yet taking people in United States
Neuromodulation for Patients With Parkinson's Disease
Where
Cambridge
Age
40 years to 85 years
People
116
Run by
Felipe Fregni, MD, PhD, MPH
See details and how to joinNCT07767006
No phaseTaking people
Using the EHR to Advance Genomic Medicine Across a Diverse Health System
Where
Philadelphia
Age
18 years and over
People
1,000
Run by
University of Pennsylvania
See details and how to joinNCT06377033
Phase 1Taking people
A Pilot Study of In-lab Dynamic Standing in Parkinson's Disease
Where
Ann Arbor
Age
50 years and over
People
5
Run by
University of Michigan
See details and how to joinNCT07543861
No phaseTaking people
Daily Amino Acid Supplementation for People With Parkinson's Disease
Where
Farmington, Storrs
Age
50 years to 90 years
People
30
Run by
Cristina Colon-Semenza
See details and how to joinNCT07115563
Phase 1/2Taking people
The University of Alabama at Birmingham (UAB) Neuroinflammation in Parkinson's Disease-TSPO- Positron Emission Tomography (PET) Substudy
Where
Birmingham
Age
30 years and over
People
205
Run by
University of Alabama at Birmingham
See details and how to joinNCT03457493
Early phase 1Taking people
Longitudinal TSPO PET Imaging With [18F]DPA-714 in PPMI (PPMI DPA-714 PET Imaging)
Where
Birmingham
Age
18 years to 99 years
People
60
Run by
University of Alabama at Birmingham
See details and how to joinNCT06289582
No phaseEnrolling by invitation
NAD Supplementation in Parkinson's Disease
Where
Oklahoma City
Age
55 years to 85 years
People
40
Run by
University of Oklahoma
See details and how to joinNCT07703137
No phaseTaking people
Young Onset Parkinson's Disease Subtypes and Pathogenic Mechanisms
Where
New York
Age
18 years and over
People
250
Run by
NYU Langone Health
See details and how to joinNCT07752355
Phase 4Taking people
Imaging Biomarkers of FOG Response to DBS
Where
Charleston
Age
40 years and over
People
54
Run by
Medical University of South Carolina
See details and how to joinNCT06951906
Phase 2Taking people
Evaluation of Tau-Pathology in Sporadic and LRRK2 Parkinson's Disease
Where
New Haven
Age
45 years to 85 years
People
60
Run by
Michael J. Fox Foundation for Parkinson's Research
See details and how to joinNCT07020026
Phase 4Taking people
Characterization of the Serotonin 2A Receptor Selective PET Tracer [18F]MH.MZ in Patients With Neurodegenerative Diseases
Where
Nashville
Age
50 years to 85 years
People
75
Run by
Vanderbilt University Medical Center
See details and how to joinNCT05357612
No phaseTaking people
Blood Pressure Effects on Cognition and Brain Blood Flow in PD
Where
San Diego
Age
50 years and over
People
60
Run by
University of California, San Diego
See details and how to joinNCT05400174
Phase 2Taking people
Psilocybin Therapy for Depression in Parkinson's Disease
Where
San Francisco
Age
40 years to 80 years
People
60
Run by
Joshua Woolley, MD, PhD
See details and how to joinNCT06455293
No phaseTaking people
Autoimmune Features of Neurodegenerative Disorders
Where
New York
Age
55 years to 90 years
People
120
Run by
Columbia University
See details and how to joinNCT04239079