Peripheral artery disease trials in United States
85 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.
- No phaseTaking peoplePROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia
- Where
- Albuquerque, Boston, Charlotte, Chicago, Cleveland, Dallas, Gainesville, Hershey, La Jolla, Lake Success, Lebanon, Milwaukee, Nashville, New Haven, New York, Norfolk, Palo Alto, Philadelphia, Pomona, San Francisco, St Louis, Tallahassee, Teaneck, Torrance, Worcester
- Age
- 18 years to 95 years
- People
- 100
- Run by
- LimFlow, Inc.
See details and how to joinNCT05313165 - No phaseTaking peopleBEETroot Juice to Reverse Functional Impairment in PAD
- Where
- Charlottesville, Chicago, Minneapolis
- Age
- 50 years and over
- People
- 210
- Run by
- Northwestern University
See details and how to joinNCT05624125 - Phase 3Taking peopleSMART Exercise for PAD
- Where
- Chicago, Minneapolis
- Age
- 50 years and over
- People
- 210
- Run by
- Northwestern University
See details and how to joinNCT06032065 - Phase 2Taking peopleFisetin to Reduce Senescence and Mobility Impairment in PAD
- Where
- Chicago
- Age
- 50 years and over
- People
- 34
- Run by
- Northwestern University
See details and how to joinNCT06399809 - No phaseTaking peopleENhancing Exercise With LIGHT to Improve Functioning in PAD
- Where
- Chicago
- Age
- 50 years and over
- People
- 32
- Run by
- Northwestern University
See details and how to joinNCT06399900 - No phaseTaking peopleMRI Guided Management of Occlusive Peripheral Arterial Disease
- Where
- Houston
- Age
- 18 years and over
- People
- 175
- Run by
- The Methodist Hospital Research Institute
See details and how to joinNCT06782100 - No phaseNot yet taking people in United StatesEvaluating the Efficacy of FoundationDRS Solo in Addition to Standard of Care for the Treatment of Non-healing Diabetic Foot Ulcers
- Where
- Hollywood
- Age
- 18 years and over
- People
- 124
- Run by
- Samaritan Biologics
See details and how to joinNCT07290673 - No phaseTaking peopleMitoQ Treatment of Claudication: Myofiber and Micro-vessel Pathology
- Where
- Omaha
- Age
- 21 years and over
- People
- 60
- Run by
- University of Nebraska
See details and how to joinNCT06409949 - No phaseTaking peopleRandomized Clinical Trial for Ewing Amputation in the VA
- Where
- Decatur, Houston, Nashville
- People
- 120
- Run by
- VA Office of Research and Development
See details and how to joinNCT05437562 - No phaseTaking peopleMulti-Center Registry for Peripheral Arterial Disease Interventions and Outcomes
- Where
- Atlanta, Austin, Boston, Chicago, Cleveland, Corpus Christi, Dallas, Davenport, Denver, Detroit, El Paso, Kingsport, Little Rock, McKinney, Muncie, New Bern, Oklahoma City, Philadelphia, San Antonio, St Louis
- People
- 14,000
- Run by
- Baylor Research Institute
See details and how to joinNCT01904851 - No phaseTaking peopleBioresorbable Sirolimus-Eluting Scaffold Treatment for Below the Knee Disease
- Where
- New York, Staten Island
- Age
- 18 years and over
- People
- 300
- Run by
- R3 Vascular Inc.
See details and how to joinNCT06071429 - No phaseTaking peopleImplementation of an Algorithm- and Multi-professional Team-supported Strategy to Improve Lipid Management of Patients With Atherosclerotic Cardiovascular Disease
- Where
- Aurora
- Age
- 18 years and over
- People
- 100
- Run by
- Colorado Prevention Center
See details and how to joinNCT07334834 - No phaseTaking peopleFuzzy Wale Compression Stockinet to Promote Healing Following Transtibial Amputation for Peripheral Arterial Disease
- Where
- Rochester
- Age
- 18 years and over
- People
- 40
- Run by
- Mayo Clinic
See details and how to joinNCT06308562 - No phaseTaking peopleOxygen-guided Supervised Exercise Therapy
- Where
- Omaha
- People
- 12
- Run by
- VA Office of Research and Development
See details and how to joinNCT06003855 - Phase 4Taking peopleAuryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone
- Where
- Baltimore, Boston, Chapel Hill, Cleveland, Gray, Greenville, Phoenix, San Diego, St Louis
- People
- 224
- Run by
- Angiodynamics, Inc.
See details and how to joinNCT06777901 - No phaseTaking peopleSirolimus Coated BALloon Versus Standard Balloon Angioplasty in The Treatment of Below The Knee Arterial Disease
- Where
- Austin, Browns Mills, Bryn Mawr, Charleston, Cincinnati, Clearwater, Cleveland, Dallas, Davenport, Des Moines, Farmington Hills, Houston, Lake Success, Los Angeles, Marlton, Miami, New York, Philadelphia, Plano, Roslyn, San Antonio, Scottsdale, Seattle, Tampa, Valhalla
- Age
- 21 years and over
- People
- 368
- Run by
- Concept Medical Inc.
See details and how to joinNCT06182397 - No phaseTaking peopleUsing Near-Infrared Light to Better Understand Peripheral Artery Disease
- Where
- Arlington
- Age
- 18 years and over
- People
- 120
- Run by
- The University of Texas at Arlington
See details and how to joinNCT07313410 - No phaseTaking peopleAssociations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status
- Where
- Charlottesville
- Age
- 18 years and over
- People
- 70
- Run by
- University of Virginia
See details and how to joinNCT06009276 - No phaseTaking peopleVascular Lab Resource (VLR) Biorepository
- Where
- Cleveland
- Age
- 18 years and over
- People
- 500
- Run by
- The Cleveland Clinic
See details and how to joinNCT05628948 - Phase 4Taking peopleInvestigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes
- Where
- Albuquerque, Aurora, Baltimore, Bay Pines, Boston, Charleston, Chicago, Cincinnati, Cleveland, Columbia, Dallas, Decatur, Durham, Gainesville, Hines, Honolulu, Houston, Huntington, Iowa City, Kansas City, Lexington, Little Rock, Loma Linda, Long Beach, Memphis, Miami, Milwaukee, Minneapolis, New York, Omaha, Palo Alto, Phoenix, Portland, Richmond, Salem, Salt Lake City, San Diego, Tucson, West Haven, West Los Angeles
- Age
- 18 years and over
- People
- 7,410
- Run by
- VA Office of Research and Development
See details and how to joinNCT02915198 - No phaseTaking peopleReal-World Registry of the Rotarex(TM) Rotational Excisional Atherectomy System (XTRACT Registry)
- Where
- Humble, Lakeland
- Age
- 22 years and over
- People
- 600
- Run by
- C. R. Bard
See details and how to joinNCT07016698 - No phaseTaking peopleSCS for Patient With Painful Diabetic Neuropathy and Peripheral Arterial Disease
- Where
- Omaha
- Age
- 19 years to 89 years
- People
- 15
- Run by
- University of Nebraska
See details and how to joinNCT06480786 - No phaseTaking peoplePeripheral Bypass Trial for Completion Control
- Where
- San Francisco
- Age
- 18 years and over
- People
- 450
- Run by
- Medistim ASA
See details and how to joinNCT06264843 - No phaseTaking peoplePounce™ Thrombectomy System Retrospective Registry
- Where
- Austin, Baton Rouge, Cleveland, Greenville, Minneapolis, Munster, Nashville, Peoria, Sioux Falls
- Age
- 18 years and over
- People
- 500
- Run by
- SurModics, Inc.
See details and how to joinNCT05868161 - Phase 3Taking peopleTemsirolimus Adventitial Delivery to Improve ANGioplasty and/or Atherectomy Revascularization Outcomes Below the Knee
- Where
- Dallas, Houma
- Age
- 18 years and over
- People
- 250
- Run by
- Mercator MedSystems, Inc.
See details and how to joinNCT04433572