Prostate cancer trials in Italy

In Italy 117 Also abroad 1480

117 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer
Where
Castelfranco Veneto, Milan, Naples, Rome
Age
18 years and over
People
100 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07287150 · EU 2025-521327-67-00
Phase 3Taking people
Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)
Where
Meldola, Milan
Age
18 years and over
People
1,310 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06136624 · EU 2023-504899-25-00
Phase 3Taking people
Diagnostic Performance of [18F]PSMA-1007 PET/CT Imaging in Patients With Newly-Diagnosed Prostate Cancer
Where
Meldola, Verona
Age
18 years and over
People
434 worldwide
Run by
ABX advanced biochemical compounds GmbH
See details and how to joinNCT06122584
No phaseNot yet taking people in Italy
A Study Comparing Single-Port and Multi-Port Robot-Assisted Surgery in Patients With Prostate or Kidney (Renal) Cancer
Where
Milan
Age
18 years and over
People
376
Run by
IRCCS San Raffaele
See details and how to joinNCT07610083
Phase 3Taking people
A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)
Where
Castelfranco Veneto, Foggia, Milan, Naples, Palermo, Rome, Rozzano, Turin
Age
18 years and over
People
1,203 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT07164443 · EU 2025-520927-26-00
Phase 3Taking people
A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer
Where
Florence, Frattamaggiore, Milan, Rome, Turin
Age
18 years and over
People
800 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT07225946 · EU 2025-522713-29-00
No phaseNot yet taking people in Italy
Assessment of Intelligent Algorithms for Detection, Diagnosis and Risk Stratification of Tumors of the Kidney and Prostate
Where
Naples
People
50 worldwide
Run by
Aristotle University Of Thessaloniki
See details and how to joinNCT07888322
Phase 3Taking people
A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.
Where
Cremona, Meldola, Milan, Naples, Rome, Rozzano, Terni, Trento, Verona
Age
18 years and over
People
900 worldwide
Run by
Pfizer
See details and how to joinNCT06629779 · EU 2024-511652-40-00
Phase 3Taking people
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
Where
Arezzo, Foggia, Milan, Rome, Rozzano, Siena, Terni, Verona
Age
18 years and over
People
1,440 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06925737 · EU 2024-517423-40-00
Phase 1/2Taking people
EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors
Where
Rome
Age
18 years and over
People
160 worldwide
Run by
Eikon Therapeutics
See details and how to joinNCT07262619 · EU 2026-525248-13-00
Phase 1/2Taking people
Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors
Where
Milan
Age
18 years and over
People
205 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07288359
No phaseTaking people
24 Gy in One Fraction Urethral-sparing "HDR Like" SBRT for Prostate Cancer
Where
Milan
Age
18 years and over
People
70
Run by
IRCCS San Raffaele
See details and how to joinNCT05936736
No phaseTaking people
Advanced Radiotherapy (ART) in Prostate Cancer (PROST-ART)
Where
Milan
Age
18 years to 95 years
People
2,500
Run by
IRCCS San Raffaele
See details and how to joinNCT06546267
Phase 2Taking people
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Where
Bergamo, Genova, Naples, Verona
Age
18 years and over
People
740 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06172478 · EU 2023-507641-29-00
Phase 1Taking people
A clinical trial to learn about the effects of INR731 alone or with an androgen receptor pathway inhibitor (ARPI) in men with prostate cancer
Where
Milan
Age
18 years and over
People
26 worldwide
Run by
Novartis Pharma AG
See details and how to join2025-524080-20-00 · EU 2025-524080-20-00
Phase 1Taking people
A Study to Investigate the Safety and Tolerability of Oral INR731 Single Agent or in Combination With Androgen Receptor Pathway Inhibitor (ARPI) in Patients With Metastatic Prostate Cancer
Where
Milan
Age
18 years and over
People
208 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07570979
Phase 2Taking people
"APalutamide and stEReotactic body radiation therapy for low burden metastatic hormone senSItive prostate cancer, a rANdomized trial -PERSIAN".
Where
Alba, Arezzo, Bologna, Candiolo, Florence, Foggia, Frattamaggiore, Genoa, Macerata, Misterbianco, Modena, Padova, Parma, Perugia, Reggio Emilia, Rome, Siena, Turin, Udine
Age
18 years and over
People
180
Run by
Fondazione Radioterapia Oncologica Onlus
See details and how to join2022-501894-37-00 · EU 2022-501894-37-00
Phase 1/2Taking people
Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer
Where
Milan, Naples, Rome, Rozzano
Age
18 years to 130 years
People
283 worldwide
Run by
AstraZeneca
See details and how to joinNCT07181161 · EU 2024-520026-11-00
Phase 3Taking people
An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.
Where
Brescia, Ferrara, Genoa, Milan, Negrar, Pisa, Rome, Rozzano
Age
18 years to 100 years
People
450 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT05939414 · EU 2022-502956-29-00
Phase 3Taking people
A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
Where
Catania, Foggia, Meldola, Milan, Terni
Age
18 years and over
People
1,314 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06136650 · EU 2023-504957-11-00
Phase 3Taking people
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
Where
Foggia, Milan, Modena, Orbassano, Peschiera del Garda, Rozzano, Trento
Age
18 years and over
People
750 worldwide
Run by
Amgen
See details and how to joinNCT07213674
Phase 2Not yet taking people in Italy
PET-Guided Navigation with Electromagnetic Tracking during PSMA-RadioGuided Surgery: Innovative Bimodal Detection of Nodal Metastases in Prostate Cancer Patients
Where
Milan
Age
18 years and over
People
54
Run by
Ospedale San Raffaele S.r.l.
See details and how to join2026-526915-12-00 · EU 2026-526915-12-00
No phaseTaking people
A Study to Learn How Men With Advanced Prostate Cancer Respond to Treatment With Darolutamide and Hormone Therapy, With or Without Chemotherapy, in Real-world Medical Practice
Where
Many Locations
Age
18 years and over
People
1,600 worldwide
Run by
Bayer
See details and how to joinNCT07344779
Phase 3Taking people
AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)
Where
Milan, Misterbianco, Naples, Negrar, Reggio Emilia, Rozzano
Age
18 years and over
People
670 worldwide
Run by
AstraZeneca
See details and how to joinNCT07611110
No phaseTaking people
PSMA-Guided Surgery and Tissue-Resident T-Cell Profiling in Node-Positive Prostate Cancer
Where
Milan
Age
18 years to 85 years
People
12
Run by
Niguarda Hospital
See details and how to joinNCT07879820