Prostate cancer trials in United Kingdom

In United Kingdom 105 Also abroad 1481

105 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors
Where
Edinburgh, London, Manchester
Age
18 years and over
People
430 worldwide
Run by
Pfizer
See details and how to joinNCT04557449 · EU 2024-512120-11-00
Phase 2Taking people
A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer
Where
Cardiff, Sutton
Age
18 years and over
People
100 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07287150 · EU 2025-521327-67-00
Phase 3Taking people
Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)
Where
Cambridge, Glasgow, London, Manchester, Truro
Age
18 years and over
People
1,310 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06136624 · EU 2023-504899-25-00
Phase 1/2Taking people
A Study Evaluating the Safety, Pharmacokinetics, and Preliminary Activity of GDC-1261 in Participants With Advanced or Metastatic Prostate Cancer
Where
Sutton
Age
18 years and over
People
260 worldwide
Run by
Genentech, Inc.
See details and how to joinNCT07567846
Phase 1Taking people
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
Where
London, Manchester
Age
18 years and over
People
460 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT06465069 · EU 2024-512927-36-00
Phase 1Enrolling by invitation
A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring
Where
Leicester, London, Plymouth
Age
18 years and over
People
120 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT06788509 · EU 2024-515457-21-00
Phase 3Taking people
Evaluating Hormone Therapy to Achieve Optimal Doses in Metastatic Prostate Cancer
Where
Huddersfield, Manchester, Sutton
Age
18 years and over
People
1,500
Run by
University College, London
See details and how to joinNCT07751133
Phase 1Taking people
A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate Cancer
Where
Cambridge, Leicester, Manchester, Sutton
Age
18 years and over
People
210 worldwide
Run by
Genentech, Inc.
See details and how to joinNCT05800665 · EU 2023-504013-68-00
Phase 1/2Taking people
Study of HLD-0915 (JNJ-101556143) in Patients With Metastatic Prostate Cancer
Where
Sutton
Age
18 years and over
People
190 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT06800313
Phase 1Taking people
A Study of JNJ-78278343 in Combination With JNJ-95298177 for Treatment of Prostate Cancer
Where
Manchester, Sutton
Age
18 years and over
People
140 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT07082920
Phase 3Taking people
A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)
Where
Birmingham, London, Manchester, Sutton
Age
18 years and over
People
1,203 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT07164443 · EU 2025-520927-26-00
Phase 3Taking people
A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer
Where
Cardiff, Glasgow, London, Newcastle upon Tyne, Preston, Sutton
Age
18 years and over
People
800 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT07225946 · EU 2025-522713-29-00
Phase 1Taking people
A Study of Pasritamig (JNJ-78278343) in Combination With JNJ-86974680 for Treatment of Prostate Cancer
Where
Manchester, Sutton
Age
18 years and over
People
40 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT07319871
Phase 3Taking people
A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.
Where
Blackburn, Chelmsford, Derby, Glasgow, Metropolitan Borough of Wirral
Age
18 years and over
People
900 worldwide
Run by
Pfizer
See details and how to joinNCT06629779 · EU 2024-511652-40-00
Phase 3Taking people
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
Where
Birmingham, Cambridge, Devon, Exeter, London, Northwood, Sutton
Age
18 years and over
People
1,440 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06925737 · EU 2024-517423-40-00
No phaseTaking people
Analysing Outcomes After Prostate Cancer Diagnosis and Treatment in Carriers of Rare Germline Mutations
Where
Sutton
Age
18 years and over
People
4,260
Run by
Institute of Cancer Research, United Kingdom
See details and how to joinNCT02705846
Phase 1Taking people
A Study of MGC026 in Participants With Advanced Solid Tumors
Where
Oxford, Sutton
Age
18 years and over
People
394 worldwide
Run by
MacroGenics
See details and how to joinNCT06242470
No phaseTaking people
The PROFILE Study: Germline Genetic Profiling: Correlation With Targeted Prostate Cancer Screening and Treatment
Where
Sutton
Age
40 years to 69 years
People
1,600
Run by
Institute of Cancer Research, United Kingdom
See details and how to joinNCT02543905
Phase 1Taking people
Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer
Where
Leicester, London, Newcastle
Age
18 years and over
People
347 worldwide
Run by
Astellas Pharma Global Development, Inc.
See details and how to joinNCT05997615 · EU 2023-503495-24-00
Phase 2Taking people
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Where
Cambridge, Coventry, London, Nottingham
Age
18 years and over
People
740 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06172478 · EU 2023-507641-29-00
Phase 1/2Taking people
Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer
Where
Cambridge, London, Plymouth, Sutton
Age
18 years to 130 years
People
283 worldwide
Run by
AstraZeneca
See details and how to joinNCT07181161 · EU 2024-520026-11-00
Phase 3Taking people
An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.
Where
Bristol, Coventry, Guildford, London
Age
18 years to 100 years
People
450 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT05939414 · EU 2022-502956-29-00
Phase 3Taking people
A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
Where
Cambridge, Derby, Glasgow, London, Manchester, Northwood, Oxford, Torquay, Truro, Windsor
Age
18 years and over
People
1,314 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06136650 · EU 2023-504957-11-00
Phase 3Taking people
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
Where
London, Sutton
Age
18 years and over
People
750 worldwide
Run by
Amgen
See details and how to joinNCT07213674
No phaseTaking people
A Study to Learn How Men With Advanced Prostate Cancer Respond to Treatment With Darolutamide and Hormone Therapy, With or Without Chemotherapy, in Real-world Medical Practice
Where
Many Locations
Age
18 years and over
People
1,600 worldwide
Run by
Bayer
See details and how to joinNCT07344779