Prostate cancer trials in United States

In United States 655 Also abroad 1489

655 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.

Phase 4Taking people
Impact of Fluciclovine (18F) PET (Positron Emission Tomography) on the Management of Prostate Cancer Following Negative or Equivocal PSMA (Prostate-Specific Membrane Antigen) PET Imaging at the Time of Biochemical Recurrence
Where
Atlanta, Austin, Boston, Portland, San Diego, St Louis
Age
18 years and over
People
142
Run by
Blue Earth Diagnostics
See details and how to joinNCT07569926
Phase 2Taking people
Study of Oral MRT-2359 With Apalutamide in Prostate Cancer
Where
Baltimore, Charlotte, Colorado Springs, East Brunswick, Fairfax, Kansas City, Lancaster, Los Angeles, Nashville, Newport Beach, Novi, Omaha, Seattle, West Valley City
Age
18 years and over
People
25
Run by
Monte Rosa Therapeutics, Inc
See details and how to joinNCT07745361
Phase 1/2Taking people
A Trial to Find Out if REGN5678 (Nezastomig) is Safe and How Well it Works Alone or in Combination With Cemiplimab for Adult Participants With Metastatic Castration-Resistant Prostate Cancer and Other Tumors
Where
Boston, Charlottesville, Columbus, Denver, Detroit, Gilbert, Houston, Jacksonville, Morgantown, New Haven, New York, Philadelphia, Phoenix, Portland, Providence, Rochester, Santa Monica, Tampa, Tucson
Age
18 years and over
People
345 worldwide
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT03972657
No phaseTaking people
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
Where
Aberdeen, Aitkin, Akron, Albert Lea, Albuquerque, Allentown, Alma, Alpena, Alton, Amarillo, Ames, Anaconda, Anchorage, Anderson, Ankeny, Ann Arbor, Antigo, Appleton, Arroyo Grande, Asheville, Ashland, Augusta, Aurora, Aventura, Baker City, Bakersfield, Ballwin, Baltimore, Baraboo, Barberton, Bardstown, Barrington, Baton Rouge, Battle Creek, Baxter, Beavercreek, Belfast, Bellingham, Belpre, Bemidji, Bend, Berlin, Bethesda, Bethlehem, Biddeford, Billings, Bismarck, Bloomington, Boardman, Boise, Bolivar, Bonita Springs, Boone, Boulder, Bozeman, Brainerd, Branson, Braselton, Brewer, Brighton, Brownstown, Brunswick, Bryan, Burbank, Burien, Burlington, Burnsville, Caldwell, Cambridge, Canton, Cape Girardeau, Carbondale, Carmichael, Caro, Carson City, Carterville, Carthage, Cary, Cedar Rapids, Centennial, Centerville, Centralia, Chaska, Chelsea, Chesapeake, Chesterfield, Cheyenne, Chicago, Chillicothe, Cincinnati, Clackamas, Clarkston, Clearwater, Clinton, Clinton Township, Clive, Clyde, Cody, Coeur d'Alene, Colorado Springs, Columbia, Columbus, Concord, Coon Rapids, Coos Bay, Corbin, Council Bluffs, Creston, Crosslake, Crystal Lake, Cudahy, Danville, Dayton, Dearborn, Decatur, Deerfield Beach, Deer River, Delaware, Denver, Des Moines, Detroit, Detroit Lakes, Dixon, Downers Grove, Dublin, Duluth, Durango, Durham, East China Township, Easton, East Stroudsburg, Eau Claire, Edgewood, Edina, Edmonds, Effingham, Elgin, Elk Grove, Elmhurst, Elmira, Ely, Emeryville, Emmett, Englewood, Enumclaw, Eureka, Everett, Evergreen Park, Fairbanks, Fargo, Farmington, Farmington Hills, Federal Way, Findlay, Fishersville, Flint, Florence, Fond du Lac, Fort Collins, Fort Dodge, Fort Lauderdale, Fort Myers, Fort Smith, Fort Thomas, Fosston, Franklin, Freehold, Fridley, Fruitland, Gaffney, Gahanna, Gainesville, Galesburg, Garden City, Garner, Georgetown, Germantown, Gladwin, Glen Burnie, Glens Falls, Goldsboro, Grafton, Grand Forks, Grand Island, Grand Rapids, Great Bend, Great Falls, Greeley, Green Bay, Greenville, Greenwood, Greer, Grosse Pointe Woods, Grove City, Hackettstown, Harvey, Havre, Hayward, Hazel Crest, Hazleton, Helena, Henderson, Hendersonville, Hibbing, Hood River, Houma, Houston, Huntington, International Falls, Issaquah, Jackson, Jacksonville, Jamaica, Jamaica Plain, Jamestown, Janesville, Jefferson, Jefferson City, Joplin, Kalamazoo, Kalispell, Kansas City, Kearney, Kennewick, Kenosha, Kettering, Kewanee, Kingman, Lacey, La Crosse, Lakeland, Lakewood, Lancaster, Lansing, Laredo, Las Cruces, Las Vegas, Leavenworth, Lewisburg, Lexington, Libertyville, Lima, Lincoln, Little Rock, Littleton, Livonia, Loma Linda, London, Lone Tree, Long Beach, Longmont, Longview, Loveland, Macomb, Madison, Manchester, Mankato, Mansfield, Maple Grove, Maplewood, Marietta, Marinette, Marion, Marlette, Marrero, Marshalltown, Martinez, Marysville, Mattoon, Meadowbrook, Mechanicsville, Medford, Medina, Merced, Meridian, Metairie, Miami Beach, Midland, Midlothian, Milwaukee, Minneapolis, Minot, Missoula, Moline, Monticello, Moose Lake, Morristown, Mount Pleasant, Mount Sterling, Mount Vernon, Mukwonago, Mullica Hill, Murrells Inlet, Muskegon, Nags Head, Nampa, Napa, Neenah, New Albany, Newark, Newberg, New Brunswick, New London, New Orleans, New Richmond, Newton, New Ulm, New York, Niles, Norfolk, Normal, Norton Shores, Novi, Oakland, Oak Lawn, Ocean Pines, Oconomowoc, Oconto Falls, O'Fallon, Oklahoma City, Olney, Omaha, Ontario, Oregon City, Osage Beach, Oshkosh, Ottawa, Paducah, Pahrump, Papillion, Parker, Park Rapids, Park Ridge, Pekin, Pennington, Peoria, Pequot Lakes, Perrysburg, Peru, Phoenix, Phoenixville, Pine River, Pittsburg, Plant City, Pompton, Pontiac, Portland, Portsmouth, Port Townsend, Post Falls, Pottstown, Princeton, Providence, Pueblo, Racine, Raleigh, Rancho Mirage, Randallstown, Reading, Redmond, Reed City, Reno, Renton, Rhinelander, Richmond, Rio Rancho, Robbinsdale, Rockford, Rocklin, Rockport, Rolla, Royal Oak, Sacramento, Safety Harbor, Saginaw, Saint Cloud, Sainte Genevieve, Saint Joseph, Saint Louis Park, Saint Paul, Salisbury, San Antonio, Sandpoint, Sandstone, Sanford, San Luis Obispo, Santa Cruz, Santa Maria, Santa Rosa, Savannah, Scarborough, Seattle, Sedro-Woolley, Shakopee, Shawano, Sheboygan, Shelton, Sheridan, Silverdale, Sioux Falls, Southfield, South Portland, Spartanburg, Spokane, Spooner, Springfield, Staples, Sterling Heights, Stevens Point, St. Helena, Stillwater, St Louis, Stockton, Stony Brook, St. Petersburg, Sturgeon Bay, Sullivan, Summit, Superior, Tacoma, Tampa, Tawas City, Thief River Falls, Thornton, Tifton, Toledo, Topeka, Towson, Traverse City, Troy, Twin Falls, Two Rivers, Union, Urbana, Vancouver, Vineland, Virginia, Virginia Beach, Waconia, Walla Walla, Walnut Creek, Warren, Warwick, Washington, Washington D.C., Waukee, Waukesha, Waupaca, Wausau, Wauwatosa, Weaverville, West Allis, West Bloomfield, West Branch, West Columbia, West Des Moines, Westerville, West Haven, Westminster, West Reading, Wichita, Wilkes-Barre, Willmar, Wilmington, Winter Haven, Wisconsin Rapids, Woodbury, Woodland, Worthington, Wyandotte, Wyoming, Yakima, Yelm, Yorkville, Youngstown, Ypsilanti, Zanesville
Age
40 years to 75 years
People
2,900
Run by
Alliance for Clinical Trials in Oncology
See details and how to joinNCT05334069
No phaseTaking people
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
Where
Austin, Charleston, Cleveland, Corbin, Duarte, Elizabethtown, Florence, Gainesville, Lexington, Memphis, Miami, Minneapolis, Nashville, New Albany, Paducah, Portland, Rochester
Age
40 years and over
People
7,000
Run by
Adela, Inc
See details and how to joinNCT05366881
No phaseTaking people
Evaluating Safety and Efficacy of Prostate-sparing Radical Cystectomy
Where
Baltimore, Washington D.C.
Age
18 years and over
People
70
Run by
Johns Hopkins University
See details and how to joinNCT05792722
Phase 1Taking people
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
Where
Atlanta, Boston, Chicago, Cleveland, Denver, Duarte, Grand Rapids, Houston, Indianapolis, La Jolla, Los Angeles, Nashville, New York, Salt Lake City, San Antonio, St Louis, St. Petersburg, West Valley City
Age
18 years and over
People
460 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT06465069 · EU 2024-512927-36-00
Phase 1Not yet taking people in United States
A Study of 177Lu-DTPA-SC16.56 in People With Neuroendocrine Carcinomas of the Lung and Prostate
Where
Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, Rockville Centre
Age
18 years and over
People
12
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT06941480
No phaseTaking people
Distance-Based Exercise to Preserve Function and Prevent Disability
Where
Boston, Butler, Cranberry Township, Dublin, Fremont, Fresno, Indiana, Kernersville, Mechanicsville, Midlothian, Modesto, Mount Airy, New Castle, Oakland, Pittsburgh, Richmond, Sacramento, San Francisco, San Jose, San Rafael, Santa Clara, Santa Rosa, Seneca, Vallejo, Walnut Creek, Winston-Salem
Age
18 years and over
People
104
Run by
Alliance for Clinical Trials in Oncology
See details and how to joinNCT07059884
Phase 1Taking people
A Study of LY4257496 in Participants With Cancer (OMNIRAY)
Where
Atlanta, Boston, Dallas, Detroit, Duarte, Grand Rapids, Houston, Miami, New York, Pittsburgh, Santa Monica, Stanford, St Louis, Tampa
Age
18 years and over
People
421 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07114601 · EU 2025-522367-15-00
No phaseTaking people
Validation of a Platelet Proteomic Assay for Diagnosing and Monitoring Prostate Cancer
Where
Durham
Age
40 years and over
People
300
Run by
Duke University
See details and how to joinNCT07144228
Phase 1Taking people
JUR-003 in Adult Patients With Metastatic Prostate Cancer
Where
Grand Rapids, Lake Success, Nashville, San Antonio
Age
18 years and over
People
210
Run by
Juri Biosciences, Inc.
See details and how to joinNCT07824349
No phaseNot yet taking people in United States
POSLUMA PET Imaging for PI-RADS 3 Prostate Lesions
Where
Avondale, Chandler, Mesa, Phoenix, Scottsdale, Surprise
Age
18 years and over
People
130
Run by
SimonMed Imaging
See details and how to joinNCT07916311
No phaseTaking people
Researching the Effect of Exercise on Cancer
Where
Basking Ridge, Commack, Durate, Harrison, Middletown, Montvale, New York, San Carlos, Uniondale
Age
18 years and over
People
51
Run by
City of Hope Medical Center
See details and how to joinNCT04589468
Phase 1Taking people
A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate Cancer
Where
Chicago, Nashville, New Haven, Orlando, Scottsdale
Age
18 years and over
People
210 worldwide
Run by
Genentech, Inc.
See details and how to joinNCT05800665 · EU 2023-504013-68-00
Phase 1Taking people
A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer
Where
Brooklyn, Grand Rapids, Mineola, New York, Philadelphia, Sarasota, St Louis
Age
18 years and over
People
300 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT05818683 · EU 2022-503132-14-00
Phase 1/2Taking people
NeoAdjuvant Theranostic Lutetium Study: The Nautilus Trial
Where
Houston
Age
18 years and over
People
6
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT06066437
Phase 1Taking people
A Study of JNJ-87189401 Combined With JNJ-78278343 for Advanced Prostate Cancer
Where
Atlanta, Aurora, Charlotte, East Brunswick, Houston, Minneapolis, Nashville, New York, Philadelphia, Portland, San Antonio, Seattle, The Bronx
Age
18 years and over
People
355 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT06095089 · EU 2023-504063-17-00
Phase 2Taking people
Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial
Where
Ames, Bettendorf, Billings, Birmingham, Bloomington, Boston, Brainerd, Brighton, Buffalo, Canton, Chapel Hill, Charleston, Chelsea, Chico, City of Saint Peters, Cleveland, Coeur d'Alene, Colorado Springs, Columbia, Columbus, Creve Coeur, Dallas, Danville, Duluth, Edgewood, Edmonds, Effingham, Encinitas, Eureka, Fargo, Fort Collins, Fort Thomas, Fort Worth, Foxborough, Gaffney, Greeley, Greer, Hackensack, Honolulu, Huntington, Iowa City, Irvine, Jupiter, Kansas City, La Jolla, Lansing, Livonia, Loveland, Marshfield, Mattoon, Mechanicsville, Menomonee Falls, Methuen, Midlothian, Milford, Millville, Milwaukee, Nashville, Newark, New York, Oak Creek, O'Fallon, Oklahoma City, Olathe, Orange, Ottawa, Overland Park, Pekin, Peoria, Peru, Portland, Rehoboth Beach, Richardson, Richmond, Sacramento, Saint Cloud, San Diego, Sayre, Seattle, Shiloh, South Weymouth, Spartanburg, Springfield, Stamford, St Louis, Topeka, Tucson, Union, Urbana, Washington, West Bend, Westwood, Ypsilanti
Age
18 years and over
People
474
Run by
Alliance for Clinical Trials in Oncology
See details and how to joinNCT06632977
Phase 1/2Taking people
Study of HLD-0915 (JNJ-101556143) in Patients With Metastatic Prostate Cancer
Where
Austin, Boston, Colorado Springs, Denver, Durham, Grand Rapids, Houston, Long Island City, Metairie, Myrtle Beach, Nashville, New Haven, Norfolk, Omaha, Sarasota, Syracuse
Age
18 years and over
People
190 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT06800313
Phase 3Taking people
Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial
Where
Ames, Anaconda, Antigo, Appleton, Atlanta, Aurora, Basking Ridge, Bemidji, Berlin Corners, Billings, Bismarck, Bloomington, Boise, Boone, Bozeman, Brighton, Brookfield, Buffalo, Burlington, Canton, Cape Girardeau, Carthage, Cedar Rapids, Centralia, Charleston, Chelsea, Cherry Hill, Chicago, Chilton, City of Saint Peters, Coeur d'Alene, Columbus, Commack, Cortland, Creve Coeur, Dallas, Danville, Decatur, Denver, Dixon, Dover, Dublin, Duluth, Durham, Edwards, Effingham, Erie, Escanaba, Eureka, Fargo, Flint, Fort Dodge, Fort Worth, Franklin, Fredericksburg, Fremont, Fresno, Fruitland, Gainesville, Galesburg, Grand Junction, Great Falls, Green Bay, Greenville, Greenwood, Harrison, Hays, Hines, Honolulu, Jefferson, Jefferson Hills, Kalispell, Kansas City, Kewanee, Lafayette, La Jolla, Lansing, Lawrence, Lawrenceville, Lee's Summit, Livonia, Lone Tree, Macomb, Madison, Marshalltown, Mattoon, Medford, Menomonee Falls, Mequon, Meridian, Middletown, Milford, Milwaukee, Missoula, Modesto, Monroeville, Montvale, Mount Vernon, Murray, Nampa, Natrona Heights, New Berlin, New York, Normal, Oak Creek, Oakland, Oconto Falls, O'Fallon, Ogden, Oklahoma City, Olathe, Oshkosh, Ottawa, Overland Park, Pekin, Peoria, Peru, Philadelphia, Pinehurst, Pittsburgh, Pontiac, Post Falls, Princeton, Racine, Rancho Mirage, Rapid City, Rhinelander, Richardson, Richmond, Roseville, Sacramento, Saint Cloud, Salina, Salt Lake City, San Diego, Sandpoint, Sandy City, San Francisco, San Jose, San Leandro, San Rafael, Santa Clara, Santa Rosa, Sayre, Sewell, Sheboygan, Shiloh, Sioux Falls, South San Francisco, Springfield, Stevens Point, St. George, St Louis, Stony Brook, Sturgeon Bay, Sylvania, Tappahannock, Topeka, Tucson, Uniondale, Urbana, Vallejo, Walnut Creek, Washington, Washington D.C., Wausau, Wauwatosa, West Bend, Westwood, Wexford, Willow Grove, Wisconsin Rapids, Ypsilanti
Age
18 years and over
People
1,260
Run by
Alliance for Clinical Trials in Oncology
See details and how to joinNCT06931340
No phaseTaking people
MATCH-UP: MAking Telehealth-Delivery of Cancer Care at Home Effective and Safe-Upscaled: A Pragmatic Cluster Randomized Trial
Where
Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, Uniondale
Age
18 years and over
People
1,750
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT06954337
Phase 1Taking people
A Study of JNJ-78278343 in Combination With JNJ-95298177 for Treatment of Prostate Cancer
Where
Cleveland, New York, Sarasota, Seattle
Age
18 years and over
People
140 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT07082920
Phase 3Taking people
A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)
Where
Ann Arbor, Aurora, Bala-Cynwyd, Baltimore, Bay Pines, Boston, Brooklyn, Charleston, Charlotte, Chattanooga, Cincinnati, Cleveland, Dallas, Detroit, Fairfax, Fort Myers, Greer, Hartford, Houston, Iowa City, La Jolla, Lakewood, Lancaster, Los Angeles, Metairie, Mineola, Minneapolis, Myrtle Beach, Nashville, New York, Norfolk, Omaha, Philadelphia, Pittsburgh, Portland, Roanoke, Salt Lake City, San Francisco, Seattle, Spartanburg, Springfield, Tampa, Washington D.C., Waukee, Wichita Falls, Winston-Salem
Age
18 years and over
People
1,203 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT07164443 · EU 2025-520927-26-00
Phase 3Taking people
Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial
Where
Ames, Anaconda, Anchorage, Ankeny, Ann Arbor, Aurora, Bakersfield, Baltimore, Basking Ridge, Battle Creek, Bel Air, Billings, Bismarck, Boone, Bozeman, Brownstown, Buffalo, Burnsville, Cambridge, Cape May Court House, Carroll, Cheyenne, Chicago, Cleveland, Clinton Township, Clive, Cody, Coeur d'Alene, Colorado Springs, Columbia, Commack, Coon Rapids, Dearborn, Decatur, DeKalb, Des Moines, Detroit, Easton, Edina, Edmonds, Egg Harbor, Fargo, Fort Dodge, Geneva, Glen Burnie, Grand Rapids, Great Falls, Harrison, Havre, Helena, Irvine, Jackson, Jefferson, Kalamazoo, Kalispell, La Jolla, Los Angeles, Lubbock, Madison, Maple Grove, Maplewood, Marshalltown, Menomonee Falls, Middletown, Milwaukee, Minneapolis, Missoula, Montvale, Mount Vernon, Newark, New Berlin, Newnan, New Richmond, New Ulm, New York, Niles, Novi, Oak Brook, Oak Creek, O'Fallon, Oklahoma City, Orange, Orland Park, Pella, Pennington, Pontiac, Portland, Post Falls, Princeton, Reed City, Richmond, Robbinsdale, Sacramento, Saint Cloud, Saint Joseph, Saint Louis Park, Saint Paul, San Diego, Sandpoint, Seattle, Shakopee, Sioux Falls, Stillwater, St Louis, The Bronx, Traverse City, Uniondale, Waconia, Warrenville, Waukee, West Bend, West Bloomfield, West Des Moines, Willmar, Woodbury, Wyandotte, Wyoming, Zion
Age
18 years and over
People
1,524
Run by
Alliance for Clinical Trials in Oncology
See details and how to joinNCT07200830