Prostate cancer trials in United States

In United States 655 Also abroad 1490

655 trials · From ClinicalTrials.gov, checked 14 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation
Where
Albany, Austin, Bethesda, Chicago, Chicago Ridge, Columbus, Greenwood, Hackensack, Hershey, Hialeah, Houston, Jacksonville, Jeffersonville, La Jolla, Lake Barrington, Lakewood, Lancaster, Los Angeles, Myrtle Beach, Nashville, Newnan, New York, Norfolk, Phoenix, Pittsburgh, Plymouth, Providence, Roanoke, Rochester, Salt Lake City, San Antonio, San Diego, San Luis Obispo, Seattle, Spring, Springfield, Syracuse, Tallahassee, Tampa, Towson, Tucson, Virginia Beach, Voorhees Township
Age
18 years and over
People
700 worldwide
Run by
AstraZeneca
See details and how to joinNCT06952803 · EU 2024-513586-39-00
Phase 3Taking people
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
Where
Alhambra, Atascadero, Avon, Bala-Cynwyd, Basking Ridge, Beverly Hills, Blacksburg, Bonney Lake, Burbank, Cary, Chandler, Charlottesville, Chattanooga, Chicago Ridge, Cincinnati, Cleveland, Commack, Cookeville, Dallas, Dalton, Decatur, Denver, Dickson, Durham, Encino, Fayetteville, Federal Way, Fort Worth, Franklin, Gallatin, Germantown, Gig Harbor, Gilbert, Glendale, Goodyear, Harrison, Hendersonville, Huntsville, Irvine, Irving, Laguna Hills, Lake Success, Lancaster, Largo, Lebanon, Long Island City, Los Angeles, Low Moor, Madison, Marina del Rey, Mentor, Mesa, Middletown, Montvale, Mount Juliet, Murfreesboro, Myrtle Beach, Nashville, New York, O'Fallon, Oklahoma City, Orange, Pasadena, Phoenix, Porter Ranch, Puyallup, Raleigh, Richardson, Ringgold, Roanoke, Rochester, Rogers, Salem, Salt Lake City, San Luis Obispo, Santa Barbara, Santa Monica, Scottsdale, Seaford, Shelbyville, Smyrna, Springdale, Tacoma, The Bronx, Torrance, Troy, Uniondale, Valencia, Ventura, Westlake Village, Wytheville
Age
18 years and over
People
1,000 worldwide
Run by
Pfizer
See details and how to joinNCT07028853 · EU 2024-519369-24-00
Phase 1/2Taking people
Phase Ib/II Platform Study of Multiple Anti-Cancer Agents in Participants With Metastatic Prostate Cancer
Where
Duarte, Encino, Houston, Metairie, Miami, Minneapolis, New York, Omaha, Orlando, Portland, South Pasadena, Tampa
Age
18 years to 99 years
People
152 worldwide
Run by
AstraZeneca
See details and how to joinNCT07590934
Early phase 1Taking people
Immunological Effects of Vitamin D Replacement Among Black/African American Prostate Cancer Patients
Where
Jacksonville, Scottsdale
Age
18 years and over
People
220
Run by
Mayo Clinic
See details and how to joinNCT05045066
Early phase 1Taking people
Magnetic Resonance (MR) Imaging With Hyperpolarized Bicarbonate (13C) to Measure Tissue pH in Prostate Cancer
Where
San Francisco
Age
18 years and over
People
10
Run by
Robert Flavell, MD, PhD
See details and how to joinNCT05851365
Phase 2Taking people
EMBRACE: Exercising Together
Where
Portland
Age
18 years and over
People
400
Run by
OHSU Knight Cancer Institute
See details and how to joinNCT06049355
No phaseTaking people
Characterizing the Genomic Landscape of Cancer in Native American Populations (NAT-Geno)
Where
Oklahoma City
Age
18 years to 100 years
People
300
Run by
University of Oklahoma
See details and how to joinNCT06960798
Phase 1/2Taking people
A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)
Where
Ann Arbor, Germantown, Los Angeles, New York, Orange, Pittsburgh, San Francisco, Seattle, Washington D.C.
Age
18 years and over
People
360 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06863272 · EU 2024-516036-94-00
Phase 1/2Taking people
An Open-label Dose Escalation and Expansion, Followed by a Phase II Study of Tulmimetostat (DZR123) and JSB462 (Luxdegalutamide) in Patients With Progressive Metastatic Castrate Resistant Prostate Cancer (mCRPC) (TulmiSTAR-01)
Where
Atlanta, Boston, Cleveland, Denver, Durham, Jacksonville, Seattle, Wichita
Age
18 years and over
People
188 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07206056 · EU 2025-521880-10-00
Phase 1/2Taking people
First-in-Human Study to Evaluate AZD8359 STEAP2 TCE in Participants With Prostate Cancer
Where
East Brunswick, Hackensack, Orlando, Providence
Age
18 years to 100 years
People
42 worldwide
Run by
AstraZeneca
See details and how to joinNCT07529717
No phaseTaking people
A Study of a New PET Scanner in People With Cancer
Where
Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, Rockville Centre
Age
18 years and over
People
90
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT07690917
Phase 3Taking people
Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer
Where
Albany, Albemarle, American Fork, Ames, Ann Arbor, Antigo, Antioch, Asheville, Atlanta, Augusta, Aurora, Aventura, Baltimore, Bath, Bellevue, Berlin Corners, Billings, Bloomington, Boiling Springs, Boulder, Bozeman, Brewer, Brighton, Brownstown, Buffalo, Burlington, Butte, Caldwell, Canton, Cape Girardeau, Carthage, Cedar City, Centerville, Chambersburg, Charleston, Charlotte, Chelsea, Chicago, Cincinnati, City of Saint Peters, Clarkston, Cleveland, Clinton Township, Clovis, Colorado Springs, Columbia, Columbus, Concord, Conroe, Coon Rapids, Coral Gables, Creve Coeur, Dallas, Dansville, Danville, Dayton, Decatur, Deerfield Beach, Denver, Des Moines, Detroit, Dover, Duarte, Dublin, Eau Claire, Edina, Edwards, Effingham, Ephrata, Eureka, Farmington Hills, Fort Collins, Fort Worth, Fremont, Fresno, Fridley, Galesburg, Gastonia, Gettysburg, Gilbert, Glens Falls, Grand Rapids, Great Falls, Greeley, Greenville, Greer, Gresham, Guilford, Hackensack, Henderson, Hendersonville, Houston, Indianapolis, Iowa City, Jackson, Jacksonville, Joplin, Kalamazoo, Kalispell, Kansas City, Kettering, Kewanee, Kirkland, La Crosse, La Jolla, Lake Success, Lansing, Las Vegas, League City, Lebanon, Lewisburg, Lexington, Little Rock, Littleton, Logan, Long Beach, Los Angeles, Louisville, Loveland, Macomb, Madison Heights, Manchester, Marshfield, Marysville, Maywood, Menomonee Falls, Metairie, Miami, Miami Beach, Midlothian, Milwaukee, Minneapolis, Minocqua, Modesto, Monroe, Morgantown, Murray, Myrtle Beach, Nampa, Nashville, Newark, New Bern, New Haven, New Richmond, New York, Oak Creek, Oakland, Ogden, Oklahoma City, Olathe, Omaha, Oneida, Orlando, Oswego, Ottawa, Overland Park, Palm Springs, Palo Alto, Parker, Pekin, Peoria, Peru, Philadelphia, Phoenix, Pittsburgh, Plantation, Pontiac, Portland, Post Falls, Princeton, Provo, Rancho Cordova, Redwood City, Rice Lake, Richardson, Richmond, Riverton, Robbinsdale, Rochester, Rock Hill, Rohnert Park, Rolla, Roseville, Sacramento, Saginaw, Sainte Genevieve, Saint Louis Park, Saint Paul, Salt Lake City, San Antonio, Sanford, San Francisco, San Jose, San Leandro, San Luis Obispo, San Rafael, Santa Clara, Santa Rosa, Scarborough, Scottsdale, Seattle, Seneca, Shakopee, South Hill, South San Francisco, Springfield, Stamford, Stevens Point, St. George, St Louis, Stockton, Stony Brook, Sugar Land, Swansea, Sylvania, Syracuse, Teaneck, Temple, The Bronx, Toledo, Traverse City, Troy, Truckee, Trumbull, Tucson, Urbana, Vacaville, Vallejo, Vancouver, Walnut Creek, Washington D.C., Waterford, Wausau, West Bend, West Bloomfield, West Chester, West Haven, Weston, Westwood, Wilkes-Barre, Wisconsin Rapids, York
Age
18 years and over
People
1,273 worldwide
Run by
SWOG Cancer Research Network
See details and how to joinNCT03678025
Phase 2Taking people
FDG-PET-Guided Metastasis Directed Radiation Therapy for the Treatment of Metastatic Hormone Sensitive Prostate Cancer, The PRTY Trial
Where
Chicago, DeKalb, Geneva, Oak Brook, Orland Park, Warrenville
Age
18 years and over
People
125
Run by
Northwestern University
See details and how to joinNCT06244004
No phaseTaking people
Exploring the Potential of Robotic Telesurgery in Remote Settings
Where
Celebration
Age
18 years to 90 years
People
10
Run by
AdventHealth
See details and how to joinNCT07130708
Phase 1/2Not yet taking people in United States
COQ10 and Vitamin E for Off-Target Radiation Toxicity
Where
Omaha
Age
19 years and over
People
200
Run by
University of Nebraska
See details and how to joinNCT07668284
No phaseEnrolling by invitation
Fusion Guided Focal Laser Ablation of Prostate Cancer
Where
Bethesda
Age
18 years to 100 years
People
30
Run by
National Institutes of Health Clinical Center (CC)
See details and how to joinNCT02759744
No phaseTaking people
Older Men's Decision Making About Active Surveillance for Prostate Cancer - Aim 3: Decision Aid Cognitive and Usability Testing
Where
Houston
Age
65 years and over
People
45
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT05497024
Phase 2Taking people
Bright White Light Therapy in Reducing Cancer-Related Fatigue and Depression in Advanced Prostate Cancer Patients Undergoing Treatment With ADT Combination Therapy
Where
Duarte
Age
60 years and over
People
210
Run by
City of Hope Medical Center
See details and how to joinNCT05869682
Phase 1/2Taking people
FOG-001 in Locally Advanced or Metastatic Solid Tumors
Where
Aurora, Baltimore, Boston, Charlottesville, Cleveland, Durham, Houston, Jacksonville, Lake Mary, Los Angeles, Madison, Minneapolis, Nashville, New Haven, New York, Palo Alto, Philadelphia, Phoenix, Pittsburgh, Portland, Rochester, San Antonio, San Francisco, Santa Monica, Scottsdale, St Louis, Tucson, Washington D.C.
Age
18 years and over
People
619 worldwide
Run by
Parabilis Medicines, Inc.
See details and how to joinNCT05919264
No phaseEnrolling by invitation
Social Determinants of Migrant Health Factors Impacting Prostate Cancer Care and Survivorship Among Sub-Saharan African and Caribbean Immigrant Men
Where
Atlanta, Houston, Rochester
Age
18 years and over
People
80
Run by
Mayo Clinic
See details and how to joinNCT06472817
Phase 2Taking people
Neoadjuvant ADT + Darolutamide With Pembrolizumab, Followed by Adjuvant Pembrolizumab in Molecularly Stratified High-Risk Prostate Cancer
Where
New York
Age
18 years and over
People
40
Run by
Icahn School of Medicine at Mount Sinai
See details and how to joinNCT07027124
No phaseNot yet taking people in United States
iCCARE Project #4: Grounded Theory Study of the Social Determinants of Migrant Health Factors Impacting Prostate Cancer Care and Survivorship Among Sub-Saharan African and Caribbean Immigrant Men Diagnosed With Prostate Cancer
Where
Houston
Age
18 years and over
People
40
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT07105020
Phase 2Not yet taking people in United States
RISK-ADAPT Protocol in Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)
Where
Washington D.C.
Age
18 years and over
People
108
Run by
Georgetown University
See details and how to joinNCT07645326
Phase 2Taking people
IL-15 Superagonist With or Without Vaccine in Biochemically Recurrent Prostate Cancer After Previous Stereotactic Body Radiation Therapy
Where
Bethesda
Age
18 years to 120 years
People
65
Run by
National Cancer Institute (NCI)
See details and how to joinNCT07686380
Phase 1Not yet taking people in United States
Testing Pasritamig Before Surgery for the Treatment of Localized Prostate Cancer
Where
Seattle
Age
18 years and over
People
18
Run by
Fred Hutchinson Cancer Center
See details and how to joinNCT07860255