Pulmonary arterial hypertension trials in France

In France 35 Also abroad 305

35 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Taking people
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Where
Angers, Brest, Grenoble Cedex 9, Le Kremlin-Bicetre, Montpellier Cedex 5, Nice, Pessac, Poitiers, Saint-Priest-en-Jarez, Strasbourg Cedex, Toulouse, Vandoeuvre Les Nancy
Age
18 years and over
People
85 worldwide
Run by
Novartis Pharma AG
See details and how to join2024-513613-12-00 · EU 2024-513613-12-00
Phase 3Taking people
An Open-Label Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Where
Le Kremlin-Bicêtre
Age
18 years and over
People
344 worldwide
Run by
Insmed Incorporated
See details and how to joinNCT07234032 · EU 2025-521769-29-00
Phase 3Taking people
A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Option
Where
Toulouse Cedex 9
Age
2 years and over
People
280 worldwide
Run by
Actelion
See details and how to joinNCT05179876 · EU 2023-506791-27-00
Phase 2Taking people
Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)
Where
Marseille, Paris, Toulouse Cedex 9
Age
1 year to 17 years
People
42 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT05587712 · EU 2023-504861-22-00
Phase 4Taking people
Initial Triple Therapy Including Parenteral Treprostinil vs Initial Double Oral Therapy in PAH Group I Patients
Where
Le Kremlin-Bicetre, Strasbourg Cedex
Age
18 years to 75 years
People
110 worldwide
Run by
AOP Orphan Pharmaceuticals AG
See details and how to joinNCT06317805 · EU 2023-504351-26-01
Phase 3Taking people
Investigational Trial to Evaluate Safety and Tolerability of Treprostinil in Children Diagnosed With PAH
Where
Paris
Age
Up to 18 years
People
20 worldwide
Run by
AOP Orphan Pharmaceuticals AG
See details and how to joinNCT06350032 · EU 2023-505082-91-00
No phaseEnrolling by invitation
A Prospective Non-interventional Observational Study to Observe Long-term Treatment and Outcomes in Pulmonary Arterial Hypertension (PAH) Patients
Where
Paris, Strasbourg
Age
18 years and over
People
110 worldwide
Run by
AOP Orphan Pharmaceuticals AG
See details and how to joinNCT06445673
Phase 2Taking people
Clinical Trial of NS-863 in Participants With Pulmonary Arterial Hypertension (PAH)
Where
Angers, Le Kremlin-Bicetre, Marseille, Rouen
Age
18 years to 75 years
People
135 worldwide
Run by
NS Pharma, Inc.
See details and how to joinNCT07441200 · EU 2025-525114-38-00
Phase 3Taking people
Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Where
Angers, Brest, Bron, Le Kremlin-Bicêtre, Lille, Marseille, Nice, Pessac, Poitiers, Saint Priest En Jarez, Strasbourg
Age
18 years and over
People
344 worldwide
Run by
Insmed Incorporated
See details and how to joinNCT07179380 · EU 2025-521558-40-00
Phase 2Taking people
Study of REGN13335 in Adult Participants With Pulmonary Arterial Hypertension (PAH)
Where
Grenoble Cedex 09, Le Kremlin-Bicetre, Pessac, Saint-Priest-en-Jarez, Strasbourg Cedex, Toulouse
Age
18 years and over
People
99 worldwide
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT07318597 · EU 2024-514754-79-00
Phase 3Taking people
A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILD
Where
Bron, Le Kremlin-Bicetre
Age
18 years to 80 years
People
344 worldwide
Run by
Liquidia Technologies, Inc.
See details and how to joinNCT07285655
Phase 3Taking people
Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)
Where
Le Kremlin Bicetre Cedex, Lille, Nice, Poitiers
Age
18 years to 75 years
People
330 worldwide
Run by
Gossamer Bio USA, Inc.
See details and how to joinNCT06274801 · EU 2023-506334-75-00
Phase 3Taking people
A Study to Evaluate the Efficacy and Safety of Once Daily Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Arterial Hypertension (PAH)
Where
Brest, Grenoble Cedex 9, Le Kremlin-Bicetre, Marseille, Poitiers, Rouen, Saint-Priest-en-Jarez, Strasbourg Cedex
Age
18 years to 75 years
People
344 worldwide
Run by
Insmed Incorporated
See details and how to joinNCT07481981 · EU 2026-525265-48-00
Phase 2Taking people
A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY)
Where
Le Kremlin-Bicetre
Age
18 years to 80 years
People
40 worldwide
Run by
AllRock Bio, Inc.
See details and how to joinNCT07175038 · EU 2025-522074-37-00
Phase 3Enrolling by invitation
A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension
Where
Brest, Bron, Rouen Cedex, Strasbourg Cedex, Vandoeuvre Les Nancy
Age
18 years and over
People
1,000 worldwide
Run by
United Therapeutics
See details and how to joinNCT03683186 · EU 2023-509305-68-00
No phaseTaking people
Cardiovascular Complications in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation.
Where
Paris
Age
15 years and over
People
400
Run by
Assistance Publique - Hôpitaux de Paris
See details and how to joinNCT07157670
Phase 3Taking people
SOFAPI
Where
Brest
Age
18 years and over
People
15
Run by
Centre Hospitalier Regional Et Universitaire De Brest
See details and how to join2025-520731-17-02 · EU 2025-520731-17-02
Phase 3Not yet taking people in France
Discontinuation Versus Continuation of Riociguat Monotherapy in Chronic Thromboembolic Pulmonary Hypertension Successfully Treated With Balloon Pulmonary Angioplasty
Where
Angers, Bordeaux, Brest, Caen, Clermont-Ferrand, Dijon, Grenoble, Le Kremlin-Bicêtre, Lille, Marseille, Montpellier, Nantes, Paris, Poitiers, Rennes, Rouen, Saint-Etienne, Strasbourg, Toulouse, Tours, Vandœuvre-lès-Nancy
Age
18 years and over
People
150
Run by
Assistance Publique - Hôpitaux de Paris
See details and how to joinNCT07644377 · EU 2026-525351-81-00
Phase 3Taking people
An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)
Where
Le Kremlin-Bicetre, Marseille, Saint-Priest-en-Jarez, Strasbourg Cedex
Age
18 years to 75 years
People
486 worldwide
Run by
Inhibikase Therapeutics
See details and how to joinNCT07365332 · EU 2024-520218-23-00
Phase 3Taking people
Tadalafil for Severe Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease
Where
Le Kremlin-Bicêtre
Age
18 years to 85 years
People
200
Run by
Assistance Publique - Hôpitaux de Paris
See details and how to joinNCT05844462
No phaseNot yet taking people in France
What is the Role of the Exposome in Pulmonary Hypertension
Where
Bordeaux, Brest, Le Kremlin-Bicêtre, Lille, Lyon, Nancy, Poitiers, Saint-Etienne, Strasbourg, Toulouse
Age
18 years and over
People
150
Run by
Poitiers University Hospital
See details and how to joinNCT07172334
Phase 1/2Taking people
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Where
Angers, Brest, Clamart, Grenoble, Montpellier, Nice, Pessac, Poitiers, Saint-Priest-en-Jarez, Strasbourg, Toulouse, Vandœuvre-lès-Nancy
Age
18 years to 100 years
People
232 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06649110
Phase 1/2Not yet taking people in France
Impact of Sotatercept on Pulmonary Artery and Right Ventricle Remodeling Imaging Assessed With 68Ga-FAPI PET/CT in Patients With PAH
Where
Brest
Age
18 years and over
People
15
Run by
University Hospital, Brest
See details and how to joinNCT07357974
Phase 2Not yet taking people in France
Effect of Vasopressin Versus Norepinephrine on Post-operative Mean Pulmonary Arterial Pressure Following Pulmonary Endarterectomy Surgery,
Where
Le Plessis-Robinson
Age
18 years and over
People
90
Run by
Fondation Hôpital Saint-Joseph
See details and how to joinNCT07614438
Phase 3Not yet taking people in France
A Phase 3 Study of Extended-release Tacrolimus in Subjects With Pulmonary Arterial Hypertension and Functional Limitations
Where
Le Kremlin-Bicetre, Strasbourg Cedex
Age
18 years to 75 years
People
300 worldwide
Run by
VIVUS LLC
See details and how to joinNCT07612657 · EU 2025-524596-24-00