Restless legs syndrome trials in United States

In United States 11 Also abroad 37

11 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.

No phaseNot yet taking people in United States
Neuromodulation to Overcome Severe Restless Legs Syndrome
Where
Birmingham
Age
18 years and over
People
15
Run by
Marshall Holland
See details and how to joinNCT07780032
Phase 2Not yet taking people in United States
Tolerability and Efficacy of CBD Extract for RLS Treatment
Where
Aurora
Age
18 years to 79 years
People
60
Run by
University of Colorado, Denver
See details and how to joinNCT07224932
No phaseTaking people
Optimizing Extended-Duration (XD-) TOMAC Therapy for Restless Legs Syndrome (RLS)
Where
Pleasanton
Age
21 years and over
People
20
Run by
Noctrix Health, Inc.
See details and how to joinNCT07675109
No phaseTaking people
The Effect of Spinal Cord Stimulators on Restless Leg Syndrome
Where
Birmingham
Age
18 years and over
People
50
Run by
University of Alabama at Birmingham
See details and how to joinNCT07179406
Phase 1/2Not yet taking people in United States
A Clinical Trial of Iron Supplementation for Youth With ADHD and Restless Sleep
Where
Baltimore
Age
8 years to 18 years
People
70
Run by
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
See details and how to joinNCT07061470
No phaseNot yet taking people in United States
The Effect of Dry Needling With Electrical Stimulation on Individuals With Restless Legs Syndrome
Where
Rochester
Age
18 years to 75 years
People
20
Run by
Mayo Clinic
See details and how to joinNCT05860751
No phaseTaking people
Peroneal Electrical Nerve Stimulation in Pregnancy for Restless Legs Syndrome
Where
Providence
Age
18 years and over
People
15
Run by
Rhode Island Hospital
See details and how to joinNCT07144631
No phaseTaking people
Observe Change in Nasal Swab DRD2 Gene Expression in Restless Legs Syndrome (RLS) Patients on Prolonged Dopamine Agonist Treatment
Where
San Francisco
Age
18 years to 60 years
People
50
Run by
HBC Immunology Inc
See details and how to joinNCT06726785
Phase 4Enrolling by invitation
Quality Improvement and Practice Based Research in Neurology Using the EMR
Where
Evanston
Age
18 years to 100 years
People
3,300
Run by
Endeavor Health
See details and how to joinNCT02670161
No phaseTaking people
Blood Changes After Exercise in Restless Legs Syndrome
Where
Stanford
Age
18 years and over
People
30
Run by
Stanford University
See details and how to joinNCT06481176
Phase 4Taking people
Nighttime Agitation and Restless Legs Syndrome in People With Alzheimer's Disease
Where
Austin
Age
55 years and over
People
156
Run by
University of Texas at Austin
See details and how to joinNCT03082755