Rheumatoid arthritis trials in Italy

In Italy 24 Also abroad 351

24 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 1Taking people
A Phase I, Open-Label Study of CLN-978 in Patients with Treatment-Refractory Rheumatoid Arthritis (RA)
Where
Rome, Rozzano
Age
18 years and over
People
56 worldwide
Run by
Cullinan Therapeutics Inc.
See details and how to join2024-519114-31-00 · EU 2024-519114-31-00
No phaseTaking people
Ultrasound to Guide Treatment Decisions in Patients With Rheumatoid Arthritis According to a T2T Approach
Where
Bruneck
Age
18 years to 84 years
People
158
Run by
Italian Society for Rheumatology
See details and how to joinNCT05717179
Phase 1Taking people
A Clinical Study of MK-1045 in People With Lupus or Rheumatoid Arthritis (MK-1045-004)
Where
Rome, Rozzano
Age
18 years to 75 years
People
21 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT07363590 · EU 2025-523412-36-00
Phase 1/2Taking people
A Study of BMS-986528 in Participants With Refractory Rheumatoid Arthritis
Where
Rome, Rozzano
Age
18 years to 65 years
People
84 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT07412704 · EU 2025-520666-22-00
No phaseTaking people
Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry
Where
Rome
Age
Up to 21 years
People
20,000 worldwide
Run by
Duke University
See details and how to joinNCT02418442
Phase 1Taking people
A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Rheumatoid Arthritis
Where
Rome, Rozzano
Age
18 years and over
People
37 worldwide
Run by
Cullinan Therapeutics Inc.
See details and how to joinNCT06994143
Phase 2Taking people
A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to Severe Rheumatoid Arthritis Who Have Not Responded to or Who Cannot Tolerate Tumor Necrosis Factor (TNF) and/or Janus Kinase (JAK Inhibitors)
Where
Reggio Emilia, Rome, Rozzano
Age
18 years and over
People
160 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07137598
Phase 2Taking people
An Extension Study to Assess Long-Term Safety and Efficacy of Afimkibart in Participants With Rheumatoid Arthritis
Where
Padova, Reggio Emilia, Rome, Rozzano
Age
18 years and over
People
120 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07620392 · EU 2025-523579-47-00
Phase 1Taking people
A Study of F8IL10 Intra-articular Treatment in Rheumatoid Arthritis
Where
Reggio Emilia, Verona
Age
18 years to 80 years
People
54
Run by
Philogen S.p.A.
See details and how to joinNCT07245992 · EU 2024-517896-19-00
No phaseTaking people
The Medacta International SMS Post-Marketing Surveillance Study
Where
Milan
Age
18 years to 75 years
People
550 worldwide
Run by
Medacta International SA
See details and how to joinNCT02748408
Phase 2Taking people
A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases
Where
Milan, Rozzano, Turin
Age
18 years to 75 years
People
220 worldwide
Run by
Amgen
See details and how to joinNCT06570798
No phaseTaking people
Exactech Shoulder Post Market Clinical Follow-up Study
Where
Catania, Eboli
Age
21 years and over
People
20,000 worldwide
Run by
Exactech
See details and how to joinNCT05603728
Phase 2Taking people
A Study to Assess the Efficacy and Safety of RO7790121 in Patients with Moderate to Severe Rheumatoid Arthritis who have not Responded to or who Cannot Tolerate TNF and/or JAK Inhibitors
Where
Padova, Reggio Emilia, Rome, Rozzano
Age
18 years and over
People
89 worldwide
Run by
F. Hoffmann-La Roche AG
See details and how to join2025-521034-28-00 · EU 2025-521034-28-00
Phase 4Taking people
3TR-PARTNER-RA
Where
Monserrato, Novara, Padova, Rozzano
Age
18 years and over
People
182 worldwide
Run by
Queen Mary University Of London
See details and how to join2024-511470-79-00 · EU 2024-511470-79-00
Phase 1Taking people
A Study to Evaluate Targeted Therapies for Patients with Rheumatoid Arthritis
Where
Ferrara, Pavia, Reggio Emilia, Rome, Rozzano
Age
18 years and over
People
19 worldwide
Run by
AbbVie Deutschland GmbH & Co. KG
See details and how to join2025-523127-21-00 · EU 2025-523127-21-00
Phase 4Taking people
The 3TR Molecular Pathobiology-Driven Precision Therapy in RA (3TR Precis-The-RA) study
Where
Milan, Monserrato, Padova, Rome, Rozzano, A.O.U Maggiore della Carità
Age
18 years and over
People
197 worldwide
Run by
Queen Mary University Of London
See details and how to join2022-502021-18-00 · EU 2022-502021-18-00
Phase 2Taking people
AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.
Where
Brescia, Milan, Rome
Age
18 years and over
People
90 worldwide
Run by
Artiva Biotherapeutics, Inc.
See details and how to joinNCT06991114 · EU 2025-520461-41-00
No phaseTaking people
Clinical Outcomes Study of the Nexel Total Elbow
Where
Torino
Age
18 years and over
People
134 worldwide
Run by
Zimmer Biomet
See details and how to joinNCT02469662
No phaseNot yet taking people in Italy
Intra-Articular Adelmidrol 2%/Hyaluronic Acid 1% With or Without m/umPEA, in Knee Pain Due to Joint Degeneration.
Where
Verona
Age
40 years and over
People
80
Run by
Universita di Verona
See details and how to joinNCT07680101
Phase 1Taking people
A Study of GSK5926371 in Participants With B-cell Driven Autoimmune Rheumatic Diseases (ARD)
Where
Ferrara, Rozzano
Age
18 years to 70 years
People
44 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT07371468 · EU 2025-522932-15-00
No phaseTaking people
Rheumatoid Arthritis Remission Screening and Prospective Surveillance
Where
Pavia
Age
18 years and over
People
200
Run by
Fondazione IRCCS Policlinico San Matteo di Pavia
See details and how to joinNCT07571993
Phase 4Taking people
MethMax trial
Where
Rozzano
Age
18 years and over
People
212 worldwide
Run by
Medical University of Vienna
See details and how to join2023-507714-27-00 · EU 2023-507714-27-00
No phaseTaking people
Radiologic Features of Rheumatoid Arthritis Interstitial Lung Disease at Chest High Resolution Computed Tomography
Where
Ferrara, Modena, Piacenza, Reggio Emilia
Age
18 years and over
People
500 worldwide
Run by
Azienda Unita Sanitaria Locale di Piacenza
See details and how to joinNCT07174102
No phaseEnrolling by invitation
G7 Dual Mobility With Vivacit-E or Longevity PMCF
Where
Milan
Age
18 years to 80 years
People
358 worldwide
Run by
Zimmer Biomet
See details and how to joinNCT05548972