Rheumatoid arthritis trials in Netherlands

In Netherlands 26 Also abroad 351

26 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 1Taking people
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.
Where
Amsterdam
Age
18 years to 70 years
People
72 worldwide
Run by
AstraZeneca
See details and how to joinNCT06916806 · EU 2024-519015-34-00
Phase 1Not yet taking people in Netherlands
A Study of BMS-986553 in Participants With Refractory Autoimmune Diseases
Where
Amsterdam, Leiden
Age
18 years and over
People
60 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT07873931
Phase 2Taking people
[18F]PEG-folate PET-CT imaging for monitoring of therapy response in Rheumatoid Arthritis patients
Where
Amsterdam, Groningen
Age
18 years and over
People
20
Run by
Amsterdam UMC Stichting
See details and how to join2024-513537-21-02 · EU 2024-513537-21-02
Phase 4Not yet taking people in Netherlands
Tapering optimisation with placebo-based mechanisms in rheumatoid arthritis: the TOP-RA trial
Where
Enschede, Hoorn Nh, Leeuwarden, Leiden, Rotterdam, 's-Gravenhage, Venlo
Age
18 years and over
People
231
Run by
Universiteit Leiden
See details and how to join2025-524593-42-00 · EU 2025-524593-42-00
Phase 2Not yet taking people in Netherlands
A study to assess the safety and efficacy of different doses of ELV001 to treat active rheumatoid arthritis in patients with an inadequate response to methotrexate and tumor necrosis factor inhibition (START SYNERGY)
Where
Amsterdam, Maastricht, Rotterdam
Age
18 years and over
People
95 worldwide
Run by
Elevara Medicines Limited
See details and how to join2025-524005-32-00 · EU 2025-524005-32-00
Phase 4Taking people
3TR-PARTNER-RA
Where
Amsterdam
Age
18 years and over
People
182 worldwide
Run by
Queen Mary University Of London
See details and how to join2024-511470-79-00 · EU 2024-511470-79-00
Phase 4Taking people
Discontinuation of Disease-modifying Anti-rheumatic Drugs (DMARDs) in Rheumatoid Arthritis Patients Also Using TNF Inhibitors
Where
Amsterdam, Rotterdam, Tilburg, Ubbergen
Age
18 years and over
People
202
Run by
Sint Maartenskliniek
See details and how to joinNCT07802678 · EU 2026-525316-33-00
Phase 1Taking people
A Study to Evaluate Targeted Therapies for Patients with Rheumatoid Arthritis
Where
Amsterdam, Leiden
Age
18 years and over
People
19 worldwide
Run by
AbbVie Deutschland GmbH & Co. KG
See details and how to join2025-523127-21-00 · EU 2025-523127-21-00
Phase 1Taking people
A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions of ABBV-319 in Adult Participants With Systemic Lupus Erythematosus (SLE), Sjogren's Disease (SjD) and Rheumatoid Arthritis (RA)
Where
Amsterdam, Utrecht
Age
18 years to 75 years
People
36 worldwide
Run by
AbbVie
See details and how to joinNCT06977724 · EU 2024-519157-10-00
Phase 4Taking people
The 3TR Molecular Pathobiology-Driven Precision Therapy in RA (3TR Precis-The-RA) study
Where
Amsterdam
Age
18 years and over
People
197 worldwide
Run by
Queen Mary University Of London
See details and how to join2022-502021-18-00 · EU 2022-502021-18-00
Phase 2Taking people
Imaging of inflamed arteries in giant cell arteritis and inflamed joints in rheumatoid arthritis with a PET/CT scan.
Where
Amsterdam, Groningen
Age
18 years and over
People
20
Run by
Universitair Medisch Centrum Groningen
See details and how to join2024-514489-38-01 · EU 2024-514489-38-01
No phaseTaking people
Clinical Outcomes Study of the Nexel Total Elbow
Where
Breda
Age
18 years and over
People
134 worldwide
Run by
Zimmer Biomet
See details and how to joinNCT02469662
Phase 1Taking people
A placebo-controlled, single-blind, phase I study in healthy volunteers and patients with Rheumatoid Arthritis with ABO21009
Where
Leiden
Age
18 years and over
People
78 worldwide
Run by
Aboleris Holdco
See details and how to join2024-517547-31-00 · EU 2024-517547-31-00
Phase 1Taking people
A phase Ib, open-label, ascending dose study to assess safety, tolerability and pharmacokinetics of PIT565 in participants with rheumatoid arthritis (RA)
Where
Leiden
Age
18 years and over
People
40 worldwide
Run by
Novartis Pharma AG
See details and how to join2024-520196-27-00 · EU 2024-520196-27-00
Phase 4Taking people
MethMax trial
Where
Leiden
Age
18 years and over
People
212 worldwide
Run by
Medical University of Vienna
See details and how to join2023-507714-27-00 · EU 2023-507714-27-00
Phase 4Taking people
REDO-JAK: Dose Reduction of Janus Kinase Inhibitors in Patients With Inflammatory Rheumatic Diseases
Where
Amsterdam, Enschede, Harderwijk, Maastricht, Nijmegen, Rotterdam, Tilburg, Ubbergen, Uden, Zwolle
Age
16 years and over
People
200
Run by
Sint Maartenskliniek
See details and how to joinNCT07160231 · EU 2025-520757-36-00
Phase 2Taking people
Fluorescence Imaging of IBD and RA Using Adalimumab-800CW
Where
Groningen
Age
18 years and over
People
36
Run by
University Medical Center Groningen
See details and how to joinNCT03938701 · EU 2024-513390-50-00
Phase 4Taking people
Better After CHoosing. Randomly Allocated or Patient Preference Based Treatment With Filgotinib or TNFi in RA (BACH)
Where
Leeuwarden
Age
18 years to 101 years
People
100
Run by
R.Bos
See details and how to joinNCT04985435
Phase 4Not yet taking people in Netherlands
Investigating the (autoreactive) B cell compartment in antibody-mediated autoimmune diseases in comparison with the recall Tetanus Toxoid response
Where
Leiden
Age
18 years and over
People
96
Run by
Leids Universitair Medisch Centrum (LUMC)
See details and how to join2024-515312-50-00 · EU 2024-515312-50-00
Phase 4Not yet taking people in Netherlands
Filgotinib bridging in newly diagnosed rheumatoid arthritis patients (FAST RA trial); A pragmatic randomized controlled non-inferiority low intervention clinical trial
Where
Enschede
Age
18 years to 64 years
People
168
Run by
Medisch Spectrum Twente
See details and how to join2024-517112-30-00 · EU 2024-517112-30-00
Phase 4Taking people
Tocilizumab Dose Optimization in Rheumatoid Arthritis
Where
Alkmaar, Amsterdam, Rotterdam, Ubbergen
Age
18 years and over
People
98
Run by
Reade revalidatie & reumatologie centrum te Amsterdam
See details and how to join2025-520513-30-00 · EU 2025-520513-30-00
No phaseEnrolling by invitation
EMDR for Persistent Pain in RA
Where
Enschede
Age
18 years and over
People
10
Run by
Medisch Spectrum Twente
See details and how to joinNCT05941559
Phase 4Taking people
Comparing the effectiveness of tofacitinib extended release (XR) chronotherapy, morning versus evening dosing, in rheumatoid arthritis (RA) and psoriatic arthritis (PsA) patients from a patient's, clinical as well as a translational point of view.
Where
Capelle aan den IJssel, Rotterdam
Age
18 years and over
People
84
Run by
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
See details and how to join2024-517865-17-01 · EU 2024-517865-17-01
No phaseTaking people
ConsideRAte Study - Splenic Stimulation for RA
Where
Amsterdam, Eindhoven
Age
22 years to 75 years
People
28 worldwide
Run by
Galvani Bioelectronics
See details and how to joinNCT05003310
No phaseTaking people
Safety of Splenic Stimulation for RA
Where
Amsterdam
Age
22 years to 75 years
People
5 worldwide
Run by
Galvani Bioelectronics
See details and how to joinNCT04955899