Rheumatoid arthritis trials in Spain

In Spain 28 Also abroad 351

28 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Taking people
A Study of AZD0120 in Autoimmune Diseases
Where
Barcelona, Madrid
Age
18 years to 75 years
People
27 worldwide
Run by
AstraZeneca
See details and how to joinNCT07295847
Phase 4Taking people
Carotid Ultrasound-Based Strategy for Primary Prevention of Cardiovascular Events in Inflammatory Rheumatic Disease (PREVENER)
Where
Barcelona, Bilbao, Ciudad Real, Córdoba, Elche, Las Palmas De Gran Canaria, Madrid, Murcia, Orihuela, Palma, San Cristóbal de La Laguna, Santander, Sant Joan d'Alacant, Torrelavega, Vitoria, Hospital laredo
Age
50 years and over
People
1,944
Run by
Instituto de Investigación Marqués de Valdecilla
See details and how to joinNCT07611747 · EU 2025-521086-28-00
Phase 1Taking people
A Clinical Study of MK-1045 in People With Lupus or Rheumatoid Arthritis (MK-1045-004)
Where
Madrid, Pamplona, Santiago de Compostela
Age
18 years to 75 years
People
21 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT07363590 · EU 2025-523412-36-00
Phase 1Taking people
Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants
Where
Barcelona, Córdoba, Madrid
Age
18 years to 65 years
People
48 worldwide
Run by
AstraZeneca
See details and how to joinNCT07201558 · EU 2025-522273-10-00
Phase 1/2Taking people
A Study of BMS-986528 in Participants With Refractory Rheumatoid Arthritis
Where
A Coruña, Córdoba
Age
18 years to 65 years
People
84 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT07412704 · EU 2025-520666-22-00
Phase 1Taking people
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.
Where
Mérida, Sevilla, Valladolid
Age
18 years to 70 years
People
72 worldwide
Run by
AstraZeneca
See details and how to joinNCT06916806 · EU 2024-519015-34-00
Phase 1/2Taking people
Controlling Hyperactive Immunity With Long-lived Lymphocytes
Where
Madrid
Age
18 years and over
People
16 worldwide
Run by
Quell Therapeutics Limited
See details and how to joinNCT07473154
Phase 2Taking people
A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to Severe Rheumatoid Arthritis Who Have Not Responded to or Who Cannot Tolerate Tumor Necrosis Factor (TNF) and/or Janus Kinase (JAK Inhibitors)
Where
La Corua, Málaga, Santiago de Compostela, Seville
Age
18 years and over
People
160 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07137598
Phase 2Taking people
An Extension Study to Assess Long-Term Safety and Efficacy of Afimkibart in Participants With Rheumatoid Arthritis
Where
A Coruña, Barcelona, Córdoba, Madrid, Málaga, Santiago de Compostela, Sevilla
Age
18 years and over
People
120 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07620392 · EU 2025-523579-47-00
Phase 1/2Taking people
Study QEL-005-CLN-01. Phase I/II study of QEL-005 in patients with diffuse cutaneous systemic sclerosis (dcSSc) and in patients with difficult to treat rheumatoid arthritis (D2TRA).
Where
Madrid
Age
18 years and over
People
8 worldwide
Run by
Quell Therapeutics Limited
See details and how to join2025-523971-46-00 · EU 2025-523971-46-00
Phase 2Taking people
A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis
Where
Barcelona, Málaga, Sabadell, Santiago de Compostela, Valencia
Age
18 years and over
People
320 worldwide
Run by
AstraZeneca
See details and how to joinNCT07276581
Phase 2Taking people
A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis
Where
A Coruña, Bilbao, Córdoba, Madrid, Sabadell, Santander, Sevilla, Valencia
Age
18 years and over
People
180 worldwide
Run by
AbbVie
See details and how to joinNCT06972446 · EU 2025-520721-21-00
Phase 2Taking people
A study to investigate how well and safe a trial drug called AZD1163, administered as an injection, works in improving symptoms and inflammation in adult participants with moderately to severely active rheumatoid arthritis.
Where
Barcelona, Málaga, Sabadell, Santiago de Compostela, Valencia
Age
18 years and over
People
97 worldwide
Run by
AstraZeneca AB
See details and how to join2025-522076-85-00 · EU 2025-522076-85-00
Phase 2Taking people
A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases
Where
Barcelona, Madrid, Santander
Age
18 years to 75 years
People
220 worldwide
Run by
Amgen
See details and how to joinNCT06570798
Phase 2Not yet taking people in Spain
A study to assess the safety and efficacy of different doses of ELV001 to treat active rheumatoid arthritis in patients with an inadequate response to methotrexate and tumor necrosis factor inhibition (START SYNERGY)
Where
Barcelona, Bilbao, Lugo, Madrid
Age
18 years and over
People
95 worldwide
Run by
Elevara Medicines Limited
See details and how to join2025-524005-32-00 · EU 2025-524005-32-00
No phaseTaking people
Vantage Mobile Bearing Total Ankle System Post Market Clinical Follow-up (Outside US)
Where
Santa Cruz de Tenerife
Age
21 years and over
People
400 worldwide
Run by
Exactech
See details and how to joinNCT05691868
Phase 2Taking people
A Study to Assess the Efficacy and Safety of RO7790121 in Patients with Moderate to Severe Rheumatoid Arthritis who have not Responded to or who Cannot Tolerate TNF and/or JAK Inhibitors
Where
A Coruña, Barcelona, Córdoba, Madrid, Málaga, Santiago de Compostela, Sevilla
Age
18 years and over
People
89 worldwide
Run by
F. Hoffmann-La Roche AG
See details and how to join2025-521034-28-00 · EU 2025-521034-28-00
Phase 4Taking people
3TR-PARTNER-RA
Where
Barcelona, Córdoba
Age
18 years and over
People
182 worldwide
Run by
Queen Mary University Of London
See details and how to join2024-511470-79-00 · EU 2024-511470-79-00
Phase 1Taking people
A Study to Evaluate Targeted Therapies for Patients with Rheumatoid Arthritis
Where
Córdoba, Sabadell, Sevilla
Age
18 years and over
People
19 worldwide
Run by
AbbVie Deutschland GmbH & Co. KG
See details and how to join2025-523127-21-00 · EU 2025-523127-21-00
No phaseTaking people
Oxidative Stress and Cardiovascular Risk in Patients With Rheumatoid Arthritis
Where
Santa Cruz de Tenerife
Age
18 years and over
People
200
Run by
University of La Laguna
See details and how to joinNCT07760662
Phase 4Taking people
The 3TR Molecular Pathobiology-Driven Precision Therapy in RA (3TR Precis-The-RA) study
Where
A Coruna, Barcelona, Córdoba
Age
18 years and over
People
197 worldwide
Run by
Queen Mary University Of London
See details and how to join2022-502021-18-00 · EU 2022-502021-18-00
Phase 2Taking people
AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.
Where
Sevilla
Age
18 years and over
People
90 worldwide
Run by
Artiva Biotherapeutics, Inc.
See details and how to joinNCT06991114 · EU 2025-520461-41-00
Phase 2Not yet taking people in Spain
Testing the safety and efficacy of combining biologic drugs in Rheumatoid and Psoriatic Arthritis
Where
Badalona, Barcelona
Age
18 years and over
People
10
Run by
Cardiff University
See details and how to join2024-518011-19-01 · EU 2024-518011-19-01
Phase 1Taking people
A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases
Where
Barcelona, Madrid
Age
18 years and over
People
125 worldwide
Run by
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
See details and how to joinNCT07115745 · EU 2024-517681-41-00
No phaseTaking people
Medical Device for Sustained Remission in Rheumatoid Arthritis Treated With Biological Therapy
Where
A Coruña, Alava, Barcelona, Madrid, Málaga, San Cristóbal de La Laguna
Age
18 years and over
People
184
Run by
Francisco J. Blanco
See details and how to joinNCT07678112