Sarcoma trials in France

In France 72 Also abroad 605

72 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Taking people
Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors
Where
Brest, Lyon, Saint-Herblain, Villejuif
Age
18 years and over
People
225 worldwide
Run by
Tango Therapeutics, Inc.
See details and how to joinNCT05732831
Phase 1/2Taking people
Phase I-II prospective trial, multicenter, open label, exploring the combination of Trabectedin plus RAdiotherapy in Soft Tissue Sarcoma patients
Where
Bordeaux, Lyon
Age
18 years and over
People
163 worldwide
Run by
Asoc Grupo Espanol De Investigacion En Sarcomas
See details and how to join2024-518199-30-00 · EU 2024-518199-30-00
Phase 1Taking people
First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors
Where
Lyon
Age
18 years and over
People
150 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06644755
Phase 4Not yet taking people in France
Innovative and Cooperative Pathway Integrating Oncogeriatric, Pharmaceutical and Pharmacological Follow-up in Elderly Patients.
Where
Villejuif
Age
70 years and over
People
794
Run by
Gustave Roussy, Cancer Campus, Grand Paris
See details and how to joinNCT07802847
Phase 1Taking people
Long-Term Follow-Up (LTFU) of Participants Treated with Adoptive Cell Therapies
Where
Pessac
People
7 worldwide
Run by
USWM Ct LLC
See details and how to join2024-513033-21-00 · EU 2024-513033-21-00
Phase 3Taking people
A Study to Investigate Efficacy & Safety of Intratumoral INT230-6 Compared to US Standard of Care in Adults With Soft Tissue Sarcomas (INVINCIBLE-3)
Where
Lyon, Nice Cedex 2, Poitiers, Villejuif
Age
18 years and over
People
333 worldwide
Run by
Intensity Therapeutics, Inc.
See details and how to joinNCT06263231 · EU 2024-512423-36-00
Phase 1/2Taking people
A Study Evaluating the Efficacy and Safety of Risvutatug Rezetecan in Participants With Advanced Sarcomas (EMBOLD Sarcoma-202)
Where
Bordeaux, Lyon, Villejuif
Age
Up to 64 years
People
14
Run by
Glaxosmithkline Research & Development Limited
See details and how to join2025-523997-18-00 · EU 2025-523997-18-00
Phase 2Taking people
Assessment of the Long-term Efficacy of Moderately Hypofractionated Neoadjuvant Radiotherapy Soft Tissue Sarcoma in the Limbs or Trunk Wall
Where
Lille
Age
18 years and over
People
135
Run by
Centre Oscar Lambret
See details and how to joinNCT07507773
No phaseTaking people
Prospective Study Evaluating the Treatment Outcomes for Localised Recurrent, Resectable Retroperitoneal Liposarcoma
Where
Paris
Age
18 years and over
People
100 worldwide
Run by
Australia and New Zealand Sarcoma Association
See details and how to joinNCT07377747
No phaseTaking people
Alpha Radiation Emitters Device (DaRT) for the Treatment of of Malignant Cutaneous Tumors
Where
Grenoble, Lyon
Age
18 years and over
People
80
Run by
Alpha Tau Medical LTD.
See details and how to joinNCT04068155
No phaseTaking people
Research of Double-positive Circulating Cells (Tumor Marker / CD45+) in Several Types of Metastatic Cancers
Where
Toulouse
Age
18 years and over
People
450
Run by
Institut Claudius Regaud
See details and how to joinNCT06967961
Phase 2Not yet taking people in France
Study of Preoperative RAdiation Therapy With Concomitant Liposomal Transcrocetin (L-TC) in Soft tISsue Sarcomas
Where
Dijon, Strasbourg
Age
18 years and over
People
42
Run by
Centre Paul Strauss
See details and how to joinNCT06476704 · EU 2024-515668-30-00
Phase 2Taking people
A Study to Evaluate Pre-operative HYPOfractionated Radiation Therapy in Aged (≥ 70 Years Old) or "Fragile" (≥ 65 Years) Patients With Limb or Trunk Soft Tissue SARComa.
Where
Bordeaux, Lille, Limoges, Lyon, Montpellier, Paris, Poitiers, Saint-Herblain, Toulouse, Villejuif
Age
65 years and over
People
48
Run by
Institut Claudius Regaud
See details and how to joinNCT06022159
Phase 1/2Taking people
A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements
Where
Dijon, Grenoble Cedex 9, Nice Cedex 2, Villejuif
Age
12 years and over
People
500 worldwide
Run by
Turning Point Therapeutics, Inc.
See details and how to joinNCT03093116 · EU 2024-512606-25-00
No phaseTaking people
The Epithelioid Hemangioendothelioma Registry of the European Reference Network on Rare Adult Solid Cancers (EURACAN)
Where
Lille, Lyon
Age
18 years and over
People
100 worldwide
Run by
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
See details and how to joinNCT06408441
Phase 2Taking people
Assessment of Compliance With Monitoring Conducted by a Physician in Person or by a Nurse in Remote Monitoring
Where
Amiens, Caen, Lille
Age
18 years and over
People
88
Run by
Centre Oscar Lambret
See details and how to joinNCT05500391
No phaseTaking people
Superiority Trial Evaluating Digitalized Information Media for Patients With Advanced Sarcomas Receiving Systemic Treatment.
Where
Besançon, Lille, Lyon, Paris, Poitiers, Rennes, Saint-Herblain, Strasbourg, Toulouse, Vandœuvre-lès-Nancy, Villejuif
Age
18 years and over
People
377
Run by
Centre Oscar Lambret
See details and how to joinNCT06211257
Phase 2Taking people
Evaluation of Clinical Impact of Interruption VS Maintenance of AI in Patients With Locally Advanced/ Metastatic Low Grade Endometrial Stromal Sarcoma (LGESS)
Where
Besancon Cedex, Bordeaux, Caen Cedex 5, Clermont-Ferrand, Lille, Limoges Cedex 1, Lyon, Marseille, Montpellier Cedex 5, Nice Cedex 2, Paris, Paris Cedex 13, Reims, Rouen Cedex, Saint-Etienne, Saint-Herblain Cedex, Saint-Priest-en-Jarez, Tours Cedex 9, Villejuif
Age
18 years to 64 years
People
40
Run by
Centre Leon Berard
See details and how to joinNCT03624244 · EU 2024-512629-97-00
Phase 3Taking people
Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas
Where
Besançon, Bordeaux, Bordeaux Cedex, Lille, Lyon, Marseille, Montpellier Cedex 5, Paris, Poitiers, Saint-Etienne, Saint-Herblain Cedex, STRASBOURG, Alsace, Strasbourg Cedex 2, Toulouse Cedex 9, Vandoeuvre Les Nancy_ Cedex, Villejuif
Age
12 years and over
People
168
Run by
Centre Leon Berard
See details and how to joinNCT04055220 · EU 2024-514637-37-00
Phase 2Taking people
Efficacy of Regorafenib Combined With Best Supportive Care as Maintenance Treatment in High Grade Bone Sarcomas Patients
Where
Besançon, Bordeaux, Dijon, Lille, Lyon, Marseille, Montpellier, Nantes, Paris, Saint-Herblain, Saint-Priest-en-Jarez, Strasbourg, Toulouse, Villejuif
Age
12 years and over
People
36
Run by
Centre Leon Berard
See details and how to joinNCT04698785
No phaseTaking people
Multimodal Immune Characterization of RAre Soft Tissue Sarcoma - MIRAS Project From SARRA (SARcome RAre) Project of the French Sarcoma Group
Where
Besançon, Bordeaux, Clermont-Ferrand, Dijon, Lille, Limoges, Lyon, Marseille, Nice, Paris, Poitiers, Reims, Rennes, Saint-Herblain, Strasbourg, Toulouse, Vandœuvre-lès-Nancy, Villejuif
Age
18 years and over
People
400
Run by
Institut Claudius Regaud
See details and how to joinNCT03967834
No phaseNot yet taking people in France
Improved Management of Soft Tissue Sarcomas Patients With an Optimized and Innovative Sorting Technology for Circulating Tumor Cells
Where
Lyon
Age
18 years and over
People
100
Run by
Centre Leon Berard
See details and how to joinNCT07401355
No phaseTaking people
Engineering Immune Organoids to Study Pediatric Cancer
Where
Paris, Villejuif
Age
Up to 25 years
People
108
Run by
Gustave Roussy, Cancer Campus, Grand Paris
See details and how to joinNCT05890781
No phaseTaking people
Prospective Biobanking Study in Cancer Patients Aiming at Better Understand the Link Between the Molecular Alterations of the Tumor Itself, Its Microenvironment and Immune Response (SCANDARE)
Where
Bordeaux, Lille, Lyon, Paris, Saint-Cloud, Vandœuvre-lès-Nancy
Age
18 years and over
People
1,050
Run by
Institut Curie
See details and how to joinNCT03017573
Phase 2Taking people
Clinical Trial Evaluating the Activity of Zanidatamab for the Treatment of Patients With Solid Tumors With an Alteration of the HER2 Gene.
Where
Angers, Beauvais, Bordeaux, Brest, Clermont Ferrand Cedex1, Dijon, Lyon, Marseille, Nice Cedex 2, Paris, Poitiers, Reims, Saint-Priest-en-Jarez, Strasbourg Cedex 2, Toulouse Cedex 9, Vandoeuvre Les Nancy_ Cedex, Villejuif
Age
18 years and over
People
105
Run by
UNICANCER
See details and how to joinNCT07192068 · EU 2025-522169-31-00