Sarcoma trials in Netherlands

In Netherlands 27 Also abroad 605

27 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Study to Evaluate the Efficacy and Safety of Divarasib Compared With Investigator's Choice of Immunotherapy or Observation in Participants With Resected Stage II-III KRAS G12C-Positive Non-Small Cell Lung Cancer (NSCLC)
Where
Geleen, 'S-Hertogenbosch
Age
18 years and over
People
400 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07541170 · EU 2025-524263-21-01
Phase 1/2Taking people
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
Where
Utrecht
Age
6 months to 25 years
People
90 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06395103 · EU 2023-507178-41-00
Phase 3Taking people
A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)
Where
Almelo, Ede Gld, Harderwijk, Utrecht, Zwolle
Age
18 years and over
People
348 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06345729 · EU 2023-507776-42-00
Phase 3Taking people
Fight Osteosarcoma Through European Research Evolving Study Platform From Diagnosis to Relapse
Where
Groningen, Leiden, Nijmegen, Utrecht
Age
4 years and over
People
530 worldwide
Run by
Gustave Roussy, Cancer Campus, Grand Paris
See details and how to joinNCT07871864
Phase 2Taking people
Pan-tumor neoadjuvant basket study of immune check-point inhibition and novel IO combinations (NEOASIS)
Where
Amsterdam
Age
18 years and over
People
153
Run by
Netherlands Cancer Institute
See details and how to joinNCT06279130 · EU 2023-505756-21-00
Phase 3Taking people
Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma
Where
Amsterdam, Leiden, Nijmegen
Age
18 years and over
People
250 worldwide
Run by
European Organisation for Research and Treatment of Cancer - EORTC
See details and how to joinNCT04031677
Phase 3Taking people
A Phase 3 Study of Ersodetug in Patients With Tumor Hyperinsulinism
Where
Rotterdam
Age
18 years and over
People
16 worldwide
Run by
Rezolute
See details and how to joinNCT06881992
Phase 1Taking people
Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas
Where
Groningen, Leiden
Age
12 years to 85 years
People
411 worldwide
Run by
Inhibrx Biosciences, Inc
See details and how to joinNCT03715933 · EU 2023-508139-29-00
Phase 1Taking people
First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors
Where
Amsterdam
Age
18 years and over
People
150 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06644755
Phase 2Taking people
KEYMAKER-U01 Substudy 01J: A Study of Pembrolizumab Plus MK-1084 in Participants With Non-Small Cell Lung Cancer (NSCLC) With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) G12C Mutations (MK-3475-01J/KEYMAKER-U01J)
Where
Deventer, Leiden
Age
18 years and over
People
140 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT07252739 · EU 2025-521939-36-00
Phase 1Taking people
Long-Term Follow-Up (LTFU) of Participants Treated with Adoptive Cell Therapies
Where
Amsterdam
People
7 worldwide
Run by
USWM Ct LLC
See details and how to join2024-513033-21-00 · EU 2024-513033-21-00
No phaseTaking people
Prospective Study Evaluating the Treatment Outcomes for Localised Recurrent, Resectable Retroperitoneal Liposarcoma
Where
Amsterdam
Age
18 years and over
People
100 worldwide
Run by
Australia and New Zealand Sarcoma Association
See details and how to joinNCT07377747
Phase 1/2Taking people
Master Protocol of TCR-modified T Cell Therapy Targeting HLA-restricted KRAS Antigen Administered in Adult Patients With Metastatic or Locally Advanced PDAC
Where
Amsterdam, Nijmegen
Age
18 years and over
People
96 worldwide
Run by
Anocca AB
See details and how to joinNCT07145450
Phase 1/2Taking people
A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements
Where
Amsterdam, Groningen
Age
12 years and over
People
500 worldwide
Run by
Turning Point Therapeutics, Inc.
See details and how to joinNCT03093116 · EU 2024-512606-25-00
Phase 2Taking people
Indocyanine Green and near infrared fLuorescence in paediatric Oncology surgery
Where
Utrecht
People
30
Run by
The University Of Birmingham
See details and how to join2024-514089-37-00 · EU 2024-514089-37-00
Phase 2/3Not yet taking people in Netherlands
The Surf trial
Where
Rotterdam
Age
18 years and over
People
40
Run by
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
See details and how to join2025-523898-42-00 · EU 2025-523898-42-00
No phaseTaking people
Short Course of Radiotherapy Prior to Surgery of Soft Tissue Sarcomas
Where
Amsterdam, Groningen, Leiden, Maastricht, Nijmegen
Age
18 years and over
People
150
Run by
The Netherlands Cancer Institute
See details and how to joinNCT07071727
Early phase 1Taking people
PET-imaging of Two Vartumabs in Patients With Solid Tumors
Where
Groningen
Age
18 years and over
People
32
Run by
Var2 Pharmaceuticals
See details and how to joinNCT06645808 · EU 2024-513827-18-00
No phaseTaking people
Outcomes Following Limb Sparing Surgery for Soft Tissue Sarcoma
Where
Amsterdam
Age
18 years and over
People
150
Run by
Amsterdam UMC
See details and how to joinNCT06962072
No phaseTaking people
Early Ageing During Therapy in AYA Cancer Patients
Where
Groningen
Age
18 years to 39 years
People
120
Run by
University Medical Center Groningen
See details and how to joinNCT05062707
Phase 1Not yet taking people in Netherlands
EPITOME-1015-I: a Study to Investigate the Safety and Tolerability of MDG1015 in Patients with Epithelial Ovarian Cancer, Gastroesophageal Adenocarcinoma, Round Cell Liposarcoma And/or Synovial Sarcoma
Where
Amsterdam, Groningen
Age
18 years and over
People
55 worldwide
Run by
Medigene AG
See details and how to joinNCT06748872 · EU 2024-516787-28-00
No phaseNot yet taking people in Netherlands
Quantitative Margin Assessment Using High-resolution Positron Emission Tomography - Computed Tomograhy
Where
Groningen
Age
18 years and over
People
30
Run by
University Medical Center Groningen
See details and how to joinNCT06726512
Phase 2/3Taking people
rEECur: International Randomised Controlled Trial of Chemotherapy for the Treatment of Recurrent and Primary Refractory Ewing Sarcoma
Where
Nijmegen, Utrecht
People
436 worldwide
Run by
The University Of Birmingham
See details and how to join2024-516078-31-00 · EU 2024-516078-31-00
Phase 1/2Taking people
FaR-RMS: An Overarching Study for Children and Adults With Frontline and Relapsed RhabdoMyoSarcoma
Where
Groningen, Utrecht
People
1,672 worldwide
Run by
University of Birmingham
See details and how to joinNCT04625907 · EU 2024-510579-40-00
No phaseTaking people
Image Assisted Optimization of Proton Radiation Therapy in Chordomas and Chondrosarcomas
Where
Delft, Leiden
Age
50 years and over
People
40
Run by
Leiden University Medical Center
See details and how to joinNCT04832620