Sickle cell disease trials in Germany

In Germany 10 Also abroad 204

8 of 10 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease
Where
Berlin, Essen, Stuttgart
Age
10 years to 65 years
People
192 worldwide
Run by
Sanofi
See details and how to joinNCT06975865
Phase 2Completed
Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis
Where
Freiburg im Breisgau
Age
12 years and over
People
70 worldwide
Run by
CSL Behring
See details and how to joinNCT06699849 · EU 2024-513440-29-00
Phase 3Taking people
A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia
Where
Berlin, Freiburg im Breisgau
Age
2 years and over
People
480 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT06609226 · EU 2024-510805-27-00
Phase 2/3Taking people
A Phase 2/3 Study of Osivelotor in Adult and Adolescent Participants With SCD
Where
Aachen, Duesseldorf, Stuttgart
Age
12 years to 64 years
People
389 worldwide
Run by
Pfizer
See details and how to joinNCT05431088 · EU 2023-508766-14-00
Phase 3Taking people
A Long-term Follow-up Study in Participants Who Received CTX001
Where
Duesseldorf, Regensburg, Tuebingen
Age
2 years to 64 years
People
160 worldwide
Run by
Vertex Pharmaceuticals Incorporated
See details and how to joinNCT04208529 · EU 2024-512654-19-00
Phase 4Active, not recruiting
Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study
Where
Heidelberg
Age
6 months to 100 years
People
130 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT04657822 · EU 2024-510734-41-00
Phase 3Taking people
Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease
Where
Duesseldorf
Age
12 years to 35 years
People
26 worldwide
Run by
Vertex Pharmaceuticals Incorporated
See details and how to joinNCT05477563 · EU 2024-514641-12-00
Phase 2Taking people
A Trial to Assess Haploidentical T-depleted Stem Cell Transplantation in Patients With SCD
Where
Aachen, Berlin, Düsseldorf, Frankfurt, Heidelberg, Regensburg, Tübingen, Würzburg
Age
2 years to 35 years
People
212 worldwide
Run by
University of Regensburg
See details and how to joinNCT04201210